Typical phthalic acid esters induce apoptosis by regulating the PI3K/Akt/Bcl-2 signaling pathway in rat insulinoma cells

Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway

(2020) Zhengguo Qiu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Neuroprotective Effects of Deuterium-Depleted Water (DDW) Against H2O2-Induced Oxidative Stress in Differentiated PC12 Cells Through the PI3K/Akt Signaling Pathway

(2020) Yongfu Wu et al.   NEUROCHEMICAL RESEARCH

Di(2-ethylhexyl) phthalate promotes hepatic fibrosis by regulation of oxidative stress and inflammation responses in rats

(2019) Zong-biao Zhao et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

A Novel Dipeptide NGF Mimetic GK-2 Selectively Activating the PI3K/AKT Signaling Pathway Promotes the Survival of Pancreatic β-Cells in a Rat Model of Diabetes

(2019) R. U. Ostrovskaya et al.   Acta Naturae

JUND regulates pancreatic β cell survival during metabolic stress

(2019) Austin L. Good et al.   Molecular Metabolism

Phthalate exposure and metabolic effects: a systematic review of the human epidemiological evidence

(2019) Elizabeth G. Radke et al.   ENVIRONMENT INTERNATIONAL

Phthalate induced oxidative stress and DNA damage in earthworms (Eisenia fetida)

(2019) Peipei Song et al.   ENVIRONMENT INTERNATIONAL

Di-(2-ethylhexyl)-phthalate induces apoptosis via the PPARγ/PTEN/AKT pathway in differentiated human embryonic stem cells

(2019) Haiqin Fang et al.   FOOD AND CHEMICAL TOXICOLOGY

Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3β/Nrf2 Pathway

(2019) Fang Wang et al.   Journal of Diabetes Research

Toxic Effects of Di-2-ethylhexyl Phthalate: An Overview

(2018) Sai Sandeep Singh Rowdhwal et al.   Biomed Research International

Autophagic and Apoptotic Pathways as Targets for Chemotherapy in Glioblastoma

(2018) Cristina Trejo-Solís et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biomonitoring and Subsequent Risk Assessment of Combined Exposure to Phthalates in Iranian Children and Adolescents

(2018) Maryam Zare Jeddi et al.   International Journal of Environmental Research and Public Health

Neural Mechanisms Underlying the Disruption of Male Courtship Behavior by Adult Exposure to Di(2-ethylhexyl) Phthalate in Mice

(2017) Carlos Dombret et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Selenium protects against cadmium-induced kidney apoptosis in chickens by activating the PI3K/AKT/Bcl-2 signaling pathway

(2017) Rong-kun Bao et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Oral exposure to dibutyl phthalate exacerbates chronic lymphocytic thyroiditis through oxidative stress in female Wistar rats

(2017) Yang Wu et al.   Scientific Reports

Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children

(2017) Amalie Carlsson et al.   Endocrine Connections

TCRP1 transcriptionally regulated by c-Myc confers cancer chemoresistance in tongue and lung cancer

(2017) Xiaoting Jia et al.   Scientific Reports

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

(2016) Lorenzo Galluzzi et al.   IMMUNITY

Regulation of cell apoptosis and proliferation in pancreatic cancer through PI3K/Akt pathway via Polo-like kinase 1

(2016) YONGHUAN MAO et al.   ONCOLOGY REPORTS

Diabetic Risk Factors Promote Islet Amyloid Polypeptide Misfolding by a Common, Membrane-mediated Mechanism

(2016) Alan K. Okada et al.   Scientific Reports

Urinary phthalate metabolites are associated with insulin resistance in obese subjects

(2015) Eveline Dirinck et al.   ENVIRONMENTAL RESEARCH

Modulation of the PI3K/Akt Pathway and Bcl-2 Family Proteins Involved in Chicken’s Tubular Apoptosis Induced by Nickel Chloride (NiCl2)

(2015) Hongrui Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endocrine-disrupting chemicals, risk of type 2 diabetes, and diabetes-related metabolic traits: A systematic review and meta-analysis

(2015) Yan Song et al.   Journal of Diabetes

Prenatal Phthalate Exposures and Neurobehavioral Development Scores in Boys and Girls at 6–10 Years of Age

(2014) Roni W. Kobrosly et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Circulating Levels of Phthalate Metabolites Are Associated With Prevalent Diabetes in the Elderly

(2012) P. M. Lind et al.   DIABETES CARE

Diethyl Hexyl Phthalate (DEHP) is associated with insulin resistance in adipose tissue of male rat: Protective role of antioxidant vitamins (C & E)

(2012) Parsanathan Rajesh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The protective effect of sonic hedgehog is mediated by the propidium iodide 3-kinase/AKT/Bcl-2 pathway in cultured rat astrocytes under oxidative stress

(2012) Y.-P. Xia et al.   NEUROSCIENCE

Cryptotanshinone from Salviae Miltiorrhizae Radix Inhibits Sodium-nitroprusside-induced Apoptosis in Neuro-2a Cells

(2012) Ramalingam Mahesh et al.   PHYTOTHERAPY RESEARCH

Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung

(2009) J. Qian et al.   MOLECULAR CANCER THERAPEUTICS

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

(2009) Jingbo Pi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Interference of pollutants with PPARs: endocrine disruption meets metabolism

(2008) C Casals-Casas et al.   INTERNATIONAL JOURNAL OF OBESITY