Emergence of dorsal-ventral polarity in ESC-derived retinal tissue

Activation of Wnt/ß-catenin signaling in ESC promotes rostral forebrain differentiation in vitro

(2015) Nozomu Takata et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

(2015) Stephan Heermann et al.   eLife

RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling

(2013) J. Steinfeld et al.   DEVELOPMENT

Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation

(2013) Anna-Carin Hägglund et al.   PLoS One

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Secreted frizzled-related proteins are required for Wnt/ -catenin signalling activation in the vertebrate optic cup

(2011) P. Esteve et al.   DEVELOPMENT

Self-organizing optic-cup morphogenesis in three-dimensional culture

(2011) Mototsugu Eiraku et al.   NATURE

Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye

(2010) G. Alfano et al.   DEVELOPMENT

Coordinated regulation of dorsal bone morphogenetic protein 4 and ventral Sonic hedgehog signaling specifies the dorso-ventral polarity in the optic vesicle and governs ocular morphogenesis through fibroblast growth factor 8 upregulation

(2010) Takuma Kobayashi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Lhx2 links the intrinsic and extrinsic factors that control optic cup formation

(2009) S. Yun et al.   DEVELOPMENT

Loss of Tbx2 delays optic vesicle invagination leading to small optic cups

(2009) Hourinaz Behesti et al.   DEVELOPMENTAL BIOLOGY

The Spatial Patterning of Mouse Cone Opsin Expression Is Regulated by Bone Morphogenetic Protein Signaling through Downstream Effector COUP-TF Nuclear Receptors

(2009) S. Satoh et al.   JOURNAL OF NEUROSCIENCE

Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain

(2009) Lanying Zhao et al.   MECHANISMS OF DEVELOPMENT

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Canonical Wnt signaling is required for the maintenance of dorsal retinal identity

(2008) E. S. Veien et al.   DEVELOPMENT

Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes

(2008) Cheng-Ji Zhou et al.   DEVELOPMENTAL DYNAMICS