Advances in rapid diagnostics for bloodstream infections

Rapid identification by MALDI-TOF/MS and antimicrobial disk diffusion susceptibility testing for positive blood cultures after a short incubation on the WASPLab

(2020) Abdessalam Cherkaoui et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Clinical Performance of the Novel GenMark Dx ePlex® Blood Culture ID Gram-Positive Panel

(2020) Karen C. Carroll et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Effect of antimicrobial stewardship with rapid MALDI-TOF identification and Vitek 2 antimicrobial susceptibility testing on hospitalization outcome

(2019) Stephen J Cavalieri et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The impact of a rapid molecular identification test on positive blood cultures from critically ill with bacteremia: A pre-post intervention study

(2019) Alexia Verroken et al.   PLoS One

Evaluation of the impact of the Accelerate Pheno™ system on time to result for differing antimicrobial stewardship intervention models in patients with gram-negative bloodstream infections

(2019) Gerald Elliott et al.   BMC INFECTIOUS DISEASES

Molecular Diagnostic Advances in Transplant Infectious Diseases

(2019) Brittany A. Young et al.   Current Infectious Disease Reports

Accuracy and applicability of different phenotypic methods for carbapenemase detection in Enterobacteriaceae: a systematic review and meta-analysis

(2019) Hong Zhong et al.   Journal of Global Antimicrobial Resistance

Emerging Technologies for Molecular Diagnosis of Sepsis

(2018) Mridu Sinha et al.   CLINICAL MICROBIOLOGY REVIEWS

The Surviving Sepsis Campaign Bundle

(2018) Mitchell M. Levy et al.   CRITICAL CARE MEDICINE

Evaluation of the Accelerate Pheno System: Results from Two Academic Medical Centers

(2018) Joseph D. Lutgring et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Multicenter Evaluation of the Accelerate PhenoTest BC Kit for Rapid Identification and Phenotypic Antimicrobial Susceptibility Testing Using Morphokinetic Cellular Analysis

(2018) Preeti Pancholi et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Recent Advances and Ongoing Challenges in the Diagnosis of Microbial Infections by MALDI-TOF Mass Spectrometry

(2018) Walter Florio et al.   Frontiers in Microbiology

Impact of matrix-assisted laser desorption/ionization time of flight mass spectrometric evaluation on the clinical outcomes of patients with bacteremia and fungemia in clinical settings lacking an antimicrobial stewardship program: a pre-post quasi experimental study

(2018) Yong Duk Jeon et al.   BMC INFECTIOUS DISEASES

Influence of GeneXpert MRSA/SA test implementation on clinical outcomes of Staphylococcus aureus bacteremia — a before–after retrospective study

(2018) Haim Ben-Zvi et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

A 5-year study of the performance of the Verigene Gram-positive blood culture panel in a pediatric hospital

(2018) Chairut Vareechon et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Evaluation of the ePlex Blood Culture Identification Panels for Detection of Pathogens in Bloodstream Infections

(2018) Te-Din Huang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of an in-house MALDI-TOF MS rapid diagnostic method for direct identification of micro-organisms from blood cultures

(2018) Yong-lu Huang et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Direct antimicrobial susceptibility tests of bacteria and yeasts from positive blood cultures by using serum separator gel tubes and MALDI–TOF MS

(2018) Shenghai Wu et al.   JOURNAL OF MICROBIOLOGICAL METHODS

The hypothetical impact of Accelerate Pheno™ system on time to effective therapy and time to definitive therapy in an institution with an established antimicrobial stewardship programme currently utilizing rapid genotypic organism/resistance marker identification

(2018) Oryan Henig et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Direct bacterial identification from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry: A systematic review and meta-analysis

(2017) Jesús Ruiz-Aragón et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

MALDI-ToF short incubation identification from blood cultures is associated with reduced length of hospitalization and a decrease in bacteremia associated mortality

(2017) J. A. Delport et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Impact of antimicrobial stewardship and rapid microarray testing on patients with Gram-negative bacteremia

(2017) K. R. Rivard et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Impact of Xpert MRSA/SA blood culture PCR assay on management of positive blood cultures in obstetric patients: a retrospective audit

(2017) A. Page et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014

(2017) Chanu Rhee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evaluation of the Accelerate Pheno System for Fast Identification and Antimicrobial Susceptibility Testing from Positive Blood Cultures in Bloodstream Infections Caused by Gram-Negative Pathogens

(2017) Matthias Marschal et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Use with Positive Blood Cultures: Methodology, Performance, and Optimization

(2017) Matthew L. Faron et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Assessment of Rapid-Blood-Culture-Identification Result Interpretation and Antibiotic Prescribing Practices

(2017) Linsey M. Donner et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Effect of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) Alone versus MALDI-TOF MS Combined with Real-Time Antimicrobial Stewardship Interventions on Time to Optimal Antimicrobial Therapy in Patients with Positive Blood Cultures

(2017) Maya Beganovic et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Effect of Molecular Rapid Diagnostic Testing on Clinical Outcomes in Bloodstream Infections: A Systematic Review and Meta-analysis

(2016) Tristan T. Timbrook et al.   CLINICAL INFECTIOUS DISEASES

Impact of rapid identification of Acinetobacter Baumannii via matrix-assisted laser desorption ionization time-of-flight mass spectrometry combined with antimicrobial stewardship in patients with pneumonia and/or bacteremia

(2016) Eric Wenzler et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Clinical and economic impact of antimicrobial stewardship interventions with the FilmArray blood culture identification panel

(2016) Joe Pardo et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Integrating Rapid Diagnostics and Antimicrobial Stewardship in Two Community Hospitals Improved Process Measures and Antibiotic Adjustment Time

(2016) Ashley M. Lockwood et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Clinical Impact of Laboratory Implementation of Verigene BC-GN Microarray-Based Assay for Detection of Gram-Negative Bacteria in Positive Blood Cultures

(2016) Tamar Walker et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of the FilmArray Blood Culture Identification Panel: Results of a Multicenter Controlled Trial

(2016) Hossein Salimnia et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Clinical Impact of MALDI-TOF MS Identification and Rapid Susceptibility Testing on Adequate Antimicrobial Treatment in Sepsis with Positive Blood Cultures

(2016) Alexia Verroken et al.   PLoS One

Quality of Care Is Improved by Rapid Short Incubation MALDI-ToF Identification from Blood Cultures as Measured by Reduced Length of Stay and Patient Outcomes as Part of a Multi-Disciplinary Approach to Bacteremia in Pediatric Patients

(2016) Johannes A. Delport et al.   PLoS One

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for the rapid identification of yeasts causing bloodstream infections

(2015) A.K. Ghosh et al.   CLINICAL MICROBIOLOGY AND INFECTION

Prospective intervention study with a microarray-based, multiplexed, automated molecular diagnosis instrument (Verigene system) for the rapid diagnosis of bloodstream infections, and its impact on the clinical outcomes

(2015) Hiromichi Suzuki et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Outcomes of Rapid Identification for Gram-Positive Bacteremia in Combination with Antibiotic Stewardship at a Community-Based Hospital System

(2015) Maggie J. Box et al.   PHARMACOTHERAPY

Performance Evaluation of the Verigene Gram-Positive and Gram-Negative Blood Culture Test for Direct Identification of Bacteria and Their Resistance Determinants from Positive Blood Cultures in Hong Kong

(2015) Gilman K. H. Siu et al.   PLoS One

MALDI-TOF MS for the Diagnosis of Infectious Diseases

(2014) R. Patel   CLINICAL CHEMISTRY

Impact of Antimicrobial Stewardship Intervention on Coagulase-Negative Staphylococcus Blood Cultures in Conjunction with Rapid Diagnostic Testing

(2014) J. L. Nagel et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia

(2014) Katherine K. Perez et al.   JOURNAL OF INFECTION

Same Day Identification and Full Panel Antimicrobial Susceptibility Testing of Bacteria from Positive Blood Culture Bottles Made Possible by a Combined Lysis-Filtration Method with MALDI-TOF VITEK Mass Spectrometry and the VITEK2 System

(2014) Alexandra Machen et al.   PLoS One

Impact of Rapid Organism Identification via Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Combined With Antimicrobial Stewardship Team Intervention in Adult Patients With Bacteremia and Candidemia

(2013) Angela M. Huang et al.   CLINICAL INFECTIOUS DISEASES

Direct Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Improves Appropriateness of Antibiotic Treatment of Bacteremia

(2012) Anne L. M. Vlek et al.   PLoS One

Validation and Implementation of the GeneXpert MRSA/SA Blood Culture Assay in a Pediatric Setting

(2011) David H. Spencer et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Clinical Impact of a Real-Time PCR Assay for Rapid Identification of Staphylococcal Bacteremia

(2011) Abigail M. Frye et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock

(2009) Anand Kumar et al.   CHEST

Identification of Methicillin-Resistant or Methicillin-Susceptible Staphylococcus aureus in Blood Cultures and Wound Swabs by GeneXpert

(2009) M. Parta et al.   JOURNAL OF CLINICAL MICROBIOLOGY