Two different sources of Perlecan cooperate for its function in the basement membrane of the Drosophila wing imaginal disc

Four specific immunoglobulin domains in UNC-52/Perlecan function with NID-1/Nidogen during dendrite morphogenesis inCaenorhabditis elegans

(2018) Kevin Celestrin et al.   DEVELOPMENT

Basement membrane mechanics shape development: Lessons from the fly

(2018) William Ramos-Lewis et al.   MATRIX BIOLOGY

Dissection of Nidogen function in Drosophila reveals tissue-specific mechanisms of basement membrane assembly

(2018) Jianli Dai et al.   PLoS Genetics

Characterization of Drosophila Nidogen/entactin reveals roles in basement membrane stability, barrier function and nervous system patterning

(2018) Georg Wolfstetter et al.   DEVELOPMENT

Differential lateral and basal tension drive folding of Drosophila wing discs through two distinct mechanisms

(2018) Liyuan Sui et al.   Nature Communications

A current view of perlecan in physiology and pathology: A mosaic of functions

(2017) Maria A. Gubbiotti et al.   MATRIX BIOLOGY

Organ sculpting by patterned extracellular matrix stiffness

(2017) Justin Crest et al.   eLife

Rab10-Mediated Secretion Synergizes with Tissue Movement to Build a Polarized Basement Membrane Architecture for Organ Morphogenesis

(2016) Adam J. Isabella et al.   DEVELOPMENTAL CELL

Tumor macrophages are pivotal constructors of tumor collagenous matrix

(2016) Ran Afik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamic regulation of basement membrane protein levels promotes egg chamber elongation in Drosophila

(2015) Adam J. Isabella et al.   DEVELOPMENTAL BIOLOGY

Companion Blood Cells Control Ovarian Stem Cell Niche Microenvironment and Homeostasis

(2015) Véronique Van De Bor et al.   Cell Reports

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes

(2015) Yiran Zang et al.   eLife

Evolution of the Perlecan/HSPG2 Gene and Its Activation in Regenerating Nematostella vectensis

(2015) Curtis R. Warren et al.   PLoS One

Crosstalk between Epithelial and Mesenchymal Tissues in Tumorigenesis and Imaginal Disc Development

(2014) Héctor Herranz et al.   CURRENT BIOLOGY

Production of Type VI Collagen by Human Macrophages: A New Dimension in Macrophage Functional Heterogeneity

(2014) M. Schnoor et al.   JOURNAL OF IMMUNOLOGY

Infiltrating Monocyte-Derived Macrophages and Resident Kupffer Cells Display Different Ontogeny and Functions in Acute Liver Injury

(2014) E. Zigmond et al.   JOURNAL OF IMMUNOLOGY

A Rab10-Dependent Mechanism for Polarized Basement Membrane Secretion during Organ Morphogenesis

(2013) David W. Lerner et al.   DEVELOPMENTAL CELL

Drosophila type XV/XVIII collagen mutants manifest integrin mediated mitochondrial dysfunction, which is improved by cyclosporin A and losartan

(2013) Ryusuke Momota et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Border patrol: Insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders

(2013) Mary C. Farach-Carson et al.   MATRIX BIOLOGY

Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/Robo Activity at the Heart Lumen

(2013) Nofar Harpaz et al.   PLoS Genetics

Monocyte-to-Macrophage Differentiation

(2012) Mary Y. Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shaping Cells and Organs in Drosophila by Opposing Roles of Fat Body-Secreted Collagen IV and Perlecan

(2011) José Carlos Pastor-Pareja et al.   DEVELOPMENTAL CELL

Drosophila type XV/XVIII collagen, Mp, is involved in Wingless distribution

(2011) Ryusuke Momota et al.   MATRIX BIOLOGY

Drosophila multiplexin (Dmp) modulates motor axon pathfinding accuracy

(2010) Frauke Meyer et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Lipoprotein Particles Cross the Blood-Brain Barrier in Drosophila

(2010) M. Brankatschk et al.   JOURNAL OF NEUROSCIENCE

Developmental and Pathogenic Mechanisms of Basement Membrane Assembly

(2009) Peter Yurchenco et al.   CURRENT PHARMACEUTICAL DESIGN

Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis

(2008) Sabina Sangaletti et al.   CANCER RESEARCH

A central function for perlecan in skeletal muscle and cardiovascular development

(2008) Jason J. Zoeller et al.   JOURNAL OF CELL BIOLOGY