Melatonin: A Potential Agent in Delaying Leaf Senescence

Delaying early leaf senescence is important for improving photosynthetic efficiency and crop productivity. Melatonin, a multitasking bio-stimulator, participates widely in plant development and stress responses. In recent years, the cumulative researches show that melatonin has the ability to delay senescence in plants. This review covers the most recent advances on the mechanisms of melatonin-mediated leaf senescence. Melatonin biosynthesis in senescing leaves employs an alternative pathway and is significantly regulated by light. Melatonin increases the thickness of leaf cuticle, wax accumulation and the ratio of palisade/spongy of senescing leaves to maintain intact leaf structure. Melatonin eliminates free radicals through a scavenging cascade reaction and induces antioxidants and antioxidant enzymes; and provides better protection against lipid peroxidation via arranging parallel to the bilayers at high concentration. Meanwhile, melatonin's ability to ensure high photosynthetic efficiency is predominantly attributed to the reduction of chlorophylls and chloroplast proteins degradation, and the acceleration of chlorophyll de novo synthesis. The dual role of melatonin-regulated autophagy is beneficial for maintaining cellular homeostasis. NACs, WRKYs and DREBs play essential roles in melatonin-controlled transcriptional reprogramming of senescing leaves. Additionally, melatonin improves the activity of cytokinin and auxin; and inhibits the action of abscisic acid, ethylene and jasmonic acid to impact indirectly leaf senescence. Epigenetic modification may be part of mechanisms of melatonin-mediated alterations in gene expression. Moreover, selection of germplasms rich in melatonin and application of genetic modification in agriculture are extensively discussed. Further studies are needed to detail the mechanisms of melatonin-mediated signaling transduction in leaf senescence.

Automated summary

Delaying leaf senescence by melatonin involves alternative biosynthesis pathways, regulation by light, and maintaining leaf structure through thickening the cuticle and increasing wax accumulation. Melatonin also acts as a scavenger of free radicals, enhances antioxidants, reduces lipid peroxidation, and promotes high photosynthetic efficiency by regulating chlorophyll levels and chlorophyll synthesis. Additionally, melatonin contributes to cellular homeostasis through autophagy regulation and transcriptional reprogramming, while impacting leaf senescence indirectly by modulating hormone actions. Further research is needed to fully understand the mechanisms of melatonin-mediated signaling in leaf senescence.