Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice

Co-occurrence of aminoglycoside and β-lactam resistance mechanisms in aminoglycoside- non-susceptible Escherichia coli isolated in the Zurich area, Switzerland

(2020) Elias Bodendoerfer et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Critical analysis of antibacterial agents in clinical development

(2020) Ursula Theuretzbacher et al.   NATURE REVIEWS MICROBIOLOGY

Abundance of Colistin-Resistant, OXA-23- and ArmA-Producing Acinetobacter baumannii Belonging to International Clone 2 in Greece

(2020) Mattia Palmieri et al.   Frontiers in Microbiology

In vitro Activity of Apramycin Against Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Isolates

(2020) Mingju Hao et al.   Frontiers in Microbiology

Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene aac(3)-IV

(2020) Michel Plattner et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin

(2020) Tomás Sou et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use

(2019) Masaaki Ishikawa et al.   Scientific Reports

Synergistic combinations and repurposed antibiotics active against the pandrug-resistant Klebsiella pneumoniae Nevada strain

(2019) Thea Brennan-Krohn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dissemination of International Clone II Acinetobacter baumannii Strains Coproducing OXA-23 Carbapenemase and 16S rRNA Methylase ArmA in Athens, Greece

(2019) Konstantina Nafplioti et al.   Microbial Drug Resistance

Efficacy of Apramycin against Multidrug-Resistant Acinetobacter baumannii in the Murine Neutropenic Thigh Model

(2018) Anthony D. Kang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients

(2018) Matthieu Boisson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Nephrotoxicity prevalence in patients treated with polymyxins: a systematic review with meta-analysis of observational studies

(2018) Ana F. Oliota et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review

(2018) Aaron J Heffernan et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii

(2018) Mario Juhas et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High incidence of pandrug-resistant Acinetobacter baumannii isolates collected from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial

(2017) J Nowak et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Aminoglycoside Resistance

(2016) Yohei Doi et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology

(2015) Anaïs Potron et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin

(2012) T. Matt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aminoglycoside modifying enzymes

(2010) Maria S. Ramirez et al.   DRUG RESISTANCE UPDATES