Role of Altered Expression, Activity and Sub-cellular Distribution of Various Histone Deacetylases (HDACs) in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis

Role of Histone Deacetylases (HDACs) in Epilepsy and Epileptogenesis

(2018) Rita Citraro et al.   CURRENT PHARMACEUTICAL DESIGN

Complex neuroprotective and neurotoxic effects of histone deacetylases

(2018) Elizabeth A. Thomas et al.   JOURNAL OF NEUROCHEMISTRY

Activating Transcription Factor 4 (ATF4) regulates neuronal activity by controlling GABABR trafficking

(2018) Carlo Corona et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy

(2018) Ralf G. Rempe et al.   JOURNAL OF NEUROSCIENCE

Wnt/β-catenin signaling as a potential target for novel epilepsy therapies

(2018) Samantha L. Hodges et al.   EPILEPSY RESEARCH

Epigenetic Histone Deacetylation Inhibition Prevents the Development and Persistence of Temporal Lobe Epilepsy

(2017) Sandesh D. Reddy et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Comparative analysis of cytokine/chemokine regulatory networks in patients with hippocampal sclerosis (HS) and focal cortical dysplasia (FCD)

(2017) Arpna Srivastava et al.   Scientific Reports

Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC)

(2017) Preethi G. Anantharaju et al.   PLoS One

Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9

(2016) S. Schwartz et al.   GENETICS

Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy

(2016) Longze Sha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of class IIa HDAC activities: it is not only matter of subcellular localization

(2016) Eros Di Giorgio et al.   Epigenomics

Synthesis, Biological Evaluation, and Computer-Aided Drug Designing of New Derivatives of Hyperactive Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitors

(2015) Song Zhang et al.   Chemical Biology & Drug Design

Rapid changes in expression of class I and IV histone deacetylases during epileptogenesis in mouse models of temporal lobe epilepsy

(2015) Rohan Jagirdar et al.   EXPERIMENTAL NEUROLOGY

Expression of class II histone deacetylases in two mouse models of temporal lobe epilepsy

(2015) Rohan Jagirdar et al.   JOURNAL OF NEUROCHEMISTRY

The Role of Wnt/β-Catenin Signaling Pathway in Disrupted Hippocampal Neurogenesis of Temporal Lobe Epilepsy: A Potential Therapeutic Target?

(2015) Cheng Huang et al.   NEUROCHEMICAL RESEARCH

Lacosamide reduces HDAC levels in the brain and improves memory: Potential for treatment of Alzheimer's disease

(2015) Shraddha R. Bang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor

(2015) Hae-Ahm Lee et al.   PLoS One

Stroke Induces Nuclear Shuttling of Histone Deacetylase 4

(2015) Haifa Kassis et al.   STROKE

Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain

(2015) Huan Gong et al.   Oncotarget

Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis

(2014) Qianfa Long et al.   BRAIN RESEARCH

Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex

(2014) Hong Geun Park et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

HDAC4 blocks autophagy to trigger podocyte injury: non-epigenetic action in diabetic nephropathy

(2014) Qingqing Wei et al.   KIDNEY INTERNATIONAL

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

(2014) Katrina J. Falkenberg et al.   NATURE REVIEWS DRUG DISCOVERY

Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response

(2014) Yunlan Du et al.   NEUROBIOLOGY OF AGING

Histone deacetylases in memory and cognition

(2014) J. Penney et al.   Science Signaling

Nuclear Calcium Signaling Regulates Nuclear Export of a Subset of Class IIa Histone Deacetylases following Synaptic Activity

(2013) Friederike Schlumm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase (HDAC) 10 Suppresses Cervical Cancer Metastasis through Inhibition of Matrix Metalloproteinase (MMP) 2 and 9 Expression

(2013) Chenlin Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyposensitivity to Gamma-Aminobutyric Acid in the Ventral Tegmental Area During Alcohol Withdrawal: Reversal by Histone Deacetylase Inhibitors

(2013) Devinder S Arora et al.   NEUROPSYCHOPHARMACOLOGY

HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo

(2013) Michal Mielcarek et al.   PLoS One

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

(2013) Michal Mielcarek et al.   PLOS BIOLOGY

Brain expression level and activity of HDAC6 protein in neurodegenerative dementia

(2012) Saori Odagiri et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased expression of matrix metalloproteinase 9 in cortical lesions from patients with focal cortical dysplasia type IIb and tuberous sclerosis complex

(2012) Song Li et al.   BRAIN RESEARCH

HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory

(2012) Richard Sando et al.   CELL

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia

(2012) Jiali Li et al.   NATURE MEDICINE

Epigenetic Mechanisms in Stroke and Epilepsy

(2012) Jee-Yeon Hwang et al.   NEUROPSYCHOPHARMACOLOGY

Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation

(2012) Anthony B. Mak et al.   Cell Reports

HDAC4 Protein Regulates HIF1α Protein Lysine Acetylation and Cancer Cell Response to Hypoxia

(2011) Hao Geng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased expression of histone deacetylases 2 in temporal lobe epilepsy: A study of epileptic patients and rat models

(2011) Yuanyuan Huang et al.   SYNAPSE

The specific role of histone deacetylase 2 in adult neurogenesis

(2010) Melanie Jawerka et al.   Neuron Glia Biology

Exogenous reelin prevents granule cell dispersion in experimental epilepsy

(2009) Martin C. Müller et al.   EXPERIMENTAL NEUROLOGY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

(2008) Alejandro Villagra et al.   NATURE IMMUNOLOGY

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY