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Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1

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Cyclin E1 Expression and Palbociclib Efficacy in Previously Treated Hormone Receptor–Positive Metastatic Breast Cancer

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CDK4 regulates lysosomal function and mTORC1 activation to promote cancer cell survival

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PI3K/mTOR Pathway Inhibition: Opportunities in Oncology and Rare Genetic Diseases

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Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma

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Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor–positive Breast Cancer

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Precision Medicine in Hormone Receptor-Positive Breast Cancer

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NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

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20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

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CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers

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Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase

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Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors

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CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors

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Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence

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