Journal
CELL BIOLOGY INTERNATIONAL
Volume 45, Issue 4, Pages 740-748Publisher
WILEY
DOI: 10.1002/cbin.11516
Keywords
antibody; coronavirus; diagnosis; IgG; IgM; SARS-CoV-2
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This paper discusses the potential application of IgM and IgG antibodies as well as viral antigens in the diagnosis of SARS-CoV-2 infection, disease progression, and recurrence of positive nucleic acid tests after discharge.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel betacoronavirus, caused a pandemic leading to a standstill of nearly all global activities. There are some controversies on the production of specific immunoglobulin M (IgM) and IgG antibodies after the infection with SARS-CoV-2. This paper seeks to elaborate on the potential application of IgM and IgG antibodies and the viral antigens for the diagnosis and the course of the disease as well as the recurrence of positive nucleic acid tests after discharge.
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