Journal
CELL AND TISSUE BANKING
Volume 22, Issue 2, Pages 249-262Publisher
SPRINGER
DOI: 10.1007/s10561-020-09885-6
Keywords
Cerebral ischemia; Cell therapy; Mesenchymal stem cells; Regenerative medicine; Stem cells
Categories
Funding
- Kashan University of Medical Sciences, Kashan, Iran
- Shahid Beheshti University of Medical Sciences, Tehran, Iran
Ask authors/readers for more resources
The main therapeutic strategies for treating cerebral ischemic injuries aim at achieving reperfusion, neuroprotection, and neurorecovery, with stem cell-based regenerative medicine emerging as a promising approach. By regenerating lost cells and restoring normal brain function, stem cells offer a potential avenue to effectively treat ischemic brain injuries.
Cerebral ischemic injury as the main manifestation of stroke can occur in stroke patients (70-80%). Nowadays, the main therapeutic strategy used for ischemic brain injury treatment aims to achieve reperfusion, neuroprotection, and neurorecovery. Also, angiogenesis as a therapeutic approach maybe represents a promising tool to enhance the prognosis of cerebral ischemic stroke. Unfortunately, although many therapeutic approaches as a life-saving gateway for cerebral ischemic injuries like pharmacotherapy and surgical treatments are widely used, they all fail to restore or regenerate damaged neurons in the brain. So, the suitable therapeutic approach would focus on regenerating the lost cells and restore the normal function of the brain. Currently, stem cell-based regenerative medicine introduced a new paradigm approach in cerebral ischemic injuries treatment. Today, in experimental researches, different types of stem cells such as mesenchymal stem cells have been applied. Therefore, stem cell-based regenerative medicine provides the opportunity to inquire and develop a more effective and safer therapeutic approach with the capability to produce and regenerate new neurons in damaged tissues.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available