Article
Cardiac & Cardiovascular Systems
Satoshi Kanazawa, Hidehiro Kaneko, Yuichiro Yano, Yuta Suzuki, Akira Okada, Satoshi Matsuoka, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Koichi Node, Hideo Yasunaga, Issei Komuro
Summary: This study analyzed the association between hypertension and incident atrial fibrillation (AF) in a large sample of adults. The results showed that both men and women with hypertension had an increased risk of AF, but the risk was higher in women. This suggests a potential sex difference in the relationship between hypertension and incident AF.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Hifza Buhari, Jiming Fang, Lu Han, Peter C. Austin, Paul Dorian, Cynthia A. Jackevicius, Amy Y. X. Yu, Moira K. Kapral, Sheldon M. Singh, Karen Tu, Dennis T. Ko, Clare L. Atzema, Emelia J. Benjamin, Douglas S. Lee, Husam Abdel-Qadir
Summary: This study aimed to examine the relationship between sex differences in age and cardiovascular care and stroke in atrial fibrillation (AF). The results showed that females had higher rates of stroke in AF even after adjusting for other factors. Older age and inequities in cardiovascular care partially explained the higher stroke rates in females with AF.
EUROPEAN HEART JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Simon Thibault, Anh-Tuan Ton, Francois Huynh, Celine Fiset
Summary: Men have a higher risk of developing atrial fibrillation than women. This study found that male mice have different atrial electrical and structural properties compared to females, and castration can reduce the susceptibility of male mice to atrial fibrillation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Jianhua Xiong, Wen Shao, Peng Yu, Jianyong Ma, Menglu Liu, Shan Huang, Xiao Liu, Kaibo Mei
Summary: This study suggests a significant linear relationship between serum uric acid (SUA) and the risk of atrial fibrillation (AF) in both men and women, with a higher risk estimate for women. Further research is needed to assess the impact of reducing SUA levels on AF incidence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Adrian Kwasny, Katarzyna Lokiec, Bartosz Uchmanowicz, Agnieszka Mlynarska, Jacek Smereka, Michal Czapla
Summary: Nutritional status is associated with the length of hospital stay for patients with atrial fibrillation. Malnutrition risk predicts prolonged hospitalization in men but not women. Body mass index does not have a significant impact on the length of hospital stay for both women and men.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Biology
Tomoki Nakamizo, Munechika Misumi, Tetsuya Takahashi, Satoshi Kurisu, Masayasu Matsumoto, Akira Tsujino
Summary: The female sex in patients with atrial fibrillation (AF) is a paradoxical risk factor for stroke, as it increases the risk among older women of certain ethnicities but contradicts the male predominance in cardiovascular diseases. Through simulations, it was found that this sex difference may be generated non-causally through left truncation due to competing risks (CR) such as coronary artery diseases. The study demonstrated that left truncation can identify spurious risk factors, and that female sex in patients with AF may be a paradoxical risk factor for stroke.
Article
Medicine, General & Internal
Gregory F. Michaud, William G. Stevenson
Summary: A 63-year-old healthy male with atrial fibrillation presents with symptoms of dyspnea and irregular heartbeat. Physical examination reveals high blood pressure, irregular pulse, and ECG confirms atrial fibrillation. Further evaluation and treatment plan are needed.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Taiki Sato, Yohei Sotomi, Shungo Hikoso, Daisaku Nakatani, Hiroya Mizuno, Katsuki Okada, Tomoharu Dohi, Tetsuhisa Kitamura, Akihiro Sunaga, Hirota Kida, Bolrathanak Oeun, Yoshio Furukawa, Akio Hirata, Yasuyuki Egami, Tetsuya Watanabe, Hitoshi Minamiguchi, Miwa Miyoshi, Nobuaki Tanaka, Takafumi Oka, Masato Okada, Takashi Kanda, Yasuhiro Matsuda, Masato Kawasaki, Masaharu Masuda, Koichi Inoue, Yasushi Sakata
Summary: This study found that the extensive ablation strategy was superior to the PVI-alone strategy in both men and women with persistent AF, with no significant difference in efficacy between the sexes.
CIRCULATION JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Alexis Hermida, Jacqueline Burtin, Maciej Kubala, Floriane Fay, Pierre-Marc Lallemand, Otilia Buiciuc, Audrey Lieu, Mustafa Zaitouni, Christophe Beyls, Jean-Sylvain Hermida
Summary: This study compared the effectiveness and complications of cryoballoon pulmonary vein isolation (cryo-PVI) in men and women with atrial fibrillation (AF). It found that a single cryo-PVI procedure for paroxysmal AF had significantly lower success rates in female patients compared to male patients, and female patients were also more likely to experience complications.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Hematology
Bernadette Corica, Trudie Lobban, Mellanie True Hills, Marco Proietti, Giulio Francesco Romiti
Summary: Female sex is associated with an increased risk of stroke in patients with atrial fibrillation (AF), although there is a trend of lower usage of oral anticoagulants in women with AF.
THROMBOSIS AND HAEMOSTASIS
(2023)
Review
Cardiac & Cardiovascular Systems
Utibe R. Essien, Jelena Kornej, Amber E. Johnson, Lucy B. Schulson, Emelia J. Benjamin, Jared W. Magnani
Summary: This review highlights the significant contributions of social determinants to the evaluation, treatment, and management of atrial fibrillation, emphasizing the important intersection between social determinants and patient outcomes. The gaps in the literature and future directions for investigating social determinants and atrial fibrillation are also identified for further research.
NATURE REVIEWS CARDIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Ya-Ting Chang, Yung-Lung Chen, Hong-Yo Kang
Summary: Sex differences play a significant role in cardiovascular and cognitive function, impacting various aspects including pathophysiology, disease onset, symptoms, and severity. Atrial fibrillation (AF) may contribute to vascular cognitive impairment (VCI), with sex hormones potentially serving as therapeutic targets for early intervention.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cardiac & Cardiovascular Systems
Reed Mszar, Daniel J. Friedman, Emily Ong, Chengan Du, Yongfei Wang, Emily P. Zeitler, Shayna D. Cunningham, Joseph Akar, Jeptha P. Curtis, James Freeman
Summary: This observational cohort study analyzed the sex-based differences and outcomes in adults undergoing catheter ablation for AF. Women were found to be older, have more comorbidities, and experience lower quality of life. They also had a higher risk of adverse events and longer hospitalization.
Article
Cardiac & Cardiovascular Systems
Andreas S. Papazoglou, Anastasios Kartas, Athanasios Samaras, Ioannis Vouloagkas, Eleni Vrana, Dimitrios V. Moysidis, Evangelos Akrivos, Georgios Kotzampasis, Amalia Baroutidou, Anastasios Papanastasiou, Evangelos Liampas, Michail Botis, Efstratios Karagiannidis, Nikolaos Stalikas, Haralambos Karvounis, Apostolos Tzikas, George Giannakoulas
Summary: The presence of diabetes mellitus on top of atrial fibrillation was associated with increased risk of all-cause mortality and cardiovascular mortality. Lower HbA1c levels were independently related to better survival rates in patients with atrial fibrillation and diabetes mellitus.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Mohit K. Turagam, Petr Neuzil, Boris Schmidt, Tobias Reichlin, Kars Neven, Andreas Metzner, Jim Hansen, Yuri Blaauw, Philippe Maury, Thomas Arentz, Philipp Sommer, Ante Anic, Frederic Anselme, Serge Boveda, Tom Deneke, Stephan Willems, Pepijn van der Voort, Roland Tilz, Moritoshi Funasako, Daniel Scherr, Reza Wakili, Daniel Steven, Josef Kautzner, Johan Vijgen, Pierre Jais, Jan Petru, Julian Chun, Laurent Roten, Anna Fueting, Marc D. Lemoine, Martin Ruwald, Bart A. Mulder, Anne Rollin, Heiko Lehrmann, Thomas Fink, Zrinka Jurisic, Corentin Chaumont, Raquel Adelino, Karin Nentwich, Melanie Gunawardene, Alexandre Ouss, Christian-Hendrik Heeger, Martin Manninger, Jan-Eric Bohnen, Arian Sultan, Petr Peichl, Pieter Koopman, Nicolas Derval, Thomas Kueffer, Vivek Y. Reddy
Summary: This study compared the differences in clinical outcomes between male and female patients undergoing pulsed field ablation (PFA) for atrial fibrillation (AF). The results showed that there were no significant sex differences in clinical effectiveness or safety events after PFA for AF.
Article
Cardiac & Cardiovascular Systems
Yuni de Framond, Mathieu Schaaf, Sophie Pichot-Lamoureux, Gregoire Range, Olivier Dubreuil, Denis Angoulvant, Marc J. Claeys, David Garcia Dorado, Thomas Bochaton, Gilles Rioufol, Claire Jossan, Inesse Boussaha, Michel Ovize, Nathan Mewton
Summary: This study aimed to assess the association of pathological Q wave evolution after reperfusion with clinical outcomes in anterior ST-segment elevation myocardial infarction (STEMI) patients. The study found that persistent Q waves after reperfusion were associated with an increased risk of heart failure or death, while Q-wave regression was associated with a significantly lower risk of events.
JOURNAL OF ELECTROCARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Quentin Brana, Frederique Thibault, Maxime Courtehoux, Gilles Metrard, Maria Joao Ribeiro, Denis Angoulvant, Matthieu Bailly
Summary: This study compared the effects of dipyridamole and regadenoson on inducing hyperemia and found that they were equally effective in comparable patients.
JOURNAL OF NUCLEAR CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Mathieu Jacobs, Arnaud Bisson, Alexandre Bodin, Dominique Babuty, Marjorie Niro, Nicolas Clementy
Review
Biochemistry & Molecular Biology
Nicolas Clementy, Alexandre Bodin, Arnaud Bisson, Ana-Paula Teixeira-Gomes, Sebastien Roger, Denis Angoulvant, Valerie Labas, Dominique Babuty
Summary: Implantable cardiac defibrillators (ICDs) are recommended for preventing sudden cardiac death, but shocks may increase mortality. Reducing electrical therapy burden improves patient prognosis. Though shocks save lives, they can also cause myocardial stunning, heart failure, and inflammatory effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Letter
Endocrinology & Metabolism
Gregoire Fauchier, Arnaud Bisson, Alexandre Bodin, Julien Herbert, Denis Angoulvant, Pierre Henri Ducluzeau, Gregory Y. H. Lip, Laurent Fauchier
Article
Cardiac & Cardiovascular Systems
Iris Ma, Thibaud Genet, Nicolas Clementy, Arnaud Bisson, Julien Herbert, Carl Semaan, Jeremie Bouteau, Denis Angoulvant, Fabrice Ivanes, Laurent Fauchier
Summary: The study found that among illicit drugs, only cannabis use was significantly associated with a higher risk of AMI. However, the prognosis of illicit drug users with AMI was similar to patients without illicit drug use.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2021)
Article
Clinical Neurology
Laurent Fauchier, Arnaud Bisson, Alexandre Bodin, Julien Herbert, Pascal Spiesser, Bertrand Pierre, Nicolas Clementy, Anne Bernard, Dominique Babuty, Gregory Y. H. Lip
Summary: Patients with hypertrophic cardiomyopathy (HCM) have a high risk of ischemic stroke (IS), particularly if they also have atrial fibrillation (AF). This French study aimed to improve risk stratification by developing a French HCM score for identifying HCM patients at higher risk of stroke. The study found that the French HCM score had good accuracy and clinical usefulness in predicting stroke in HCM patients.
Article
Medicine, General & Internal
Juqian Zhang, Arnaud Bisson, Gregoire Fauchier, Alexandre Bodin, Julien Herbert, Pierre Henri Ducluzeau, Gregory Y. H. Lip, Laurent Fauchier
Summary: This study investigated the incidence of stroke and bleeding in atrial fibrillation (AF) patients with concurrent hyperthyroidism, finding that hyperthyroidism is an independent risk factor for ischemic stroke in AF patients, particularly in the first year after diagnosis.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Alexandre Bodin, Nicolas Clementy, Arnaud Bisson, Bertrand Pierre, Julien Herbert, Dominique Babuty, Laurent Fauchier
Summary: Patients treated with leadless ventricular permanent pacemakers had better clinical outcomes within the first month compared to those treated with conventional VVI pacemakers. However, during a midterm follow-up, the risk of all-cause death, cardiovascular death, and endocarditis in patients with leadless VVI pacemakers was not statistically different after propensity score matching.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Review
Cardiac & Cardiovascular Systems
Amal Aidoud, Wassim Gana, Fanny Poitau, Camille Debacq, Victoire Leroy, Jacques-Alexis Nkodo, Pierre Poupin, Denis Angoulvant, Bertrand Fougere
Summary: As the population ages, the global burden of cardiovascular disease is increasing, especially in older adults. This review examines noncardiovascular factors that interact with health status and quality of life in older people with cardiovascular disease. The focus is on geriatric conditions that pose a major risk of decline in function and have a significant impact on overall prognosis.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Medicine, General & Internal
Ameenathul M. M. Fawzy, Arnaud Bisson, Alexandre Bodin, Julien Herbert, Gregory Y. H. Lip, Laurent Fauchier
Summary: This study investigated the association between atrial fibrillation (AF) and ventricular arrhythmias (VAs) and sudden death in hospitalized patients in France. The results showed that AF patients had significantly higher incidence and risk of VAs and cardiac arrest compared to non-AF patients. This association remained significant after adjusting for confounders, indicating a clear association between AF and VAs and sudden death.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Antoine Roger, Yves Cottin, Sid Ahmed Bentounes, Arnaud Bisson, Alexandre Bodin, Julien Herbert, Baptiste Maille, Marianne Zeller, Jean Claude Deharo, Gregory Y. H. Lip, Laurent Fauchier
Summary: The European Heart Rhythm Association (EHRA) proposed an algorithm for the screening and management of arrhythmias using digital devices. This study analyzed the incidence rates of atrial fibrillation (AF) based on the EHRA algorithm and identified higher-risk subgroups.
Article
Peripheral Vascular Disease
Jean-Michel Halimi, Jean-Baptiste de Freminville, Philippe Gatault, Arnaud Bisson, Benedicte Sautenet, Valentin Maisons, Pascal Vigny, Denis Angoulvant, Laurent Fauchier
Summary: This study investigated the characteristics and prognosis of hypertensive encephalopathy (HE) and found that HE had a poor prognosis with high risks of death and other complications. Hypertension and concomitant stroke significantly influenced the prognosis of HE.
Article
Cardiac & Cardiovascular Systems
Thibault Lenormand, Kassem Abou Khalil, Alexandre Bodin, Dominique Babuty, Arnaud Bisson, Nicolas Clementy
Summary: This study compared the use of VR and AV systems in sinus rhythm patients with chronic ventricular pacing for complete atrioventricular block. The results showed that using the AV system provided significant atrioventricular synchrony and did not lead to pacemaker syndrome.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Editorial Material
Medicine, General & Internal
Denis Angoulvant