Circulating leukocyte–platelet complexes as a predictive biomarker for the development of immune-related adverse events in advanced non-small cell lung cancer patients receiving anti-PD-(L)1 blocking agents

Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial

(2019) Howard West et al.   LANCET ONCOLOGY

Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion

(2019) Patrice Marques et al.   Journal of Clinical Medicine

Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer

(2019) Matthew D. Hellmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inverse Association Between Circulating Monocyte-Platelet Complexes and Inflammation in Ulcerative Colitis Patients

(2018) Carlos Zamora et al.   INFLAMMATORY BOWEL DISEASES

Immune-Related Adverse Events Associated with Immune Checkpoint Blockade

(2018) Michael A. Postow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of Immune-Related Adverse Events With Nivolumab Efficacy in Non–Small-Cell Lung Cancer

(2018) Koji Haratani et al.   JAMA Oncology

Pembrolizumab plus Chemotherapy for Squamous Non–Small-Cell Lung Cancer

(2018) Luis Paz-Ares et al.   NEW ENGLAND JOURNAL OF MEDICINE

Importance of endoscopic and histological evaluation in the management of immune checkpoint inhibitor-induced colitis

(2018) Hamzah Abu-Sbeih et al.   Journal for ImmunoTherapy of Cancer

Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1–Based Immunotherapy

(2018) Su Y. Lim et al.   CLINICAL CANCER RESEARCH

Profiling Preexisting Antibodies in Patients Treated With Anti–PD-1 Therapy for Advanced Non–Small Cell Lung Cancer

(2018) Yukihiro Toi et al.   JAMA Oncology

Pneumonitis in Patients Treated With Anti–Programmed Death-1/Programmed Death Ligand 1 Therapy

(2017) Jarushka Naidoo et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety Profile of Nivolumab Monotherapy: A Pooled Analysis of Patients With Advanced Melanoma

(2017) Jeffrey S. Weber et al.   JOURNAL OF CLINICAL ONCOLOGY

Binding of Platelets to Lymphocytes: A Potential Anti-Inflammatory Therapy in Rheumatoid Arthritis

(2017) Carlos Zamora et al.   JOURNAL OF IMMUNOLOGY

Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

(2017) Achim Rittmeyer et al.   LANCET

Evaluation of serum IL-17 levels during ipilimumab therapy: Correlation with colitis.

(2017) M. K. Callahan et al.   JOURNAL OF CLINICAL ONCOLOGY

Platelet microparticles inhibit IL-17 production by regulatory T cells through P-selectin

(2016) S. Dinkla et al.   BLOOD

Diverse types of dermatologic toxicities from immune checkpoint blockade therapy

(2016) Jonathan L. Curry et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Platelets Play Differential Role During the Initiation and Progression of Autoimmune NeuroinflammationNovelty and Significance

(2015) Sarah C. Starossom et al.   CIRCULATION RESEARCH

Platelets in cancer metastasis: To help the “villain” to do evil

(2015) Nailin Li   INTERNATIONAL JOURNAL OF CANCER

Metastasis-promoting role of extravasated platelet activation in tumor

(2015) Tomoharu Miyashita et al.   JOURNAL OF SURGICAL RESEARCH

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

(2015) Julie Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune Checkpoint Blockade

(2014) Jarushka Naidoo et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Platelets induce a proinflammatory phenotype in monocytes via the CD147 pathway in rheumatoid arthritis

(2014) Meng-yao Rong et al.   ARTHRITIS RESEARCH & THERAPY

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Endocrine Side Effects Induced by Immune Checkpoint Inhibitors

(2013) Salvatore Maria Corsello et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Functional consequences of platelet binding to T lymphocytes in inflammation

(2013) Carlos Zamora et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cytokine Secretion from Human Monocytes Potentiated by P-Selectin-Mediated Cell Adhesion

(2012) Junsuke Suzuki et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Modulation of Natural Killer Cell Anti-Tumor Reactivity by Platelets

(2011) Theresa Placke et al.   Journal of Innate Immunity

Update on Immunologic Therapy With Anti–CTLA-4 Antibodies in Melanoma: Identification of Clinical and Biological Response Patterns, Immune-Related Adverse Events, and Their Management

(2010) Katharina C. Kaehler et al.   SEMINARS IN ONCOLOGY

Platelet-lymphocyte cross-talk

(2008) Nailin Li   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases

(2008) J. M. van Gils et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Circulating platelet–leukocyte aggregates: A marker of microvascular injury in diabetic patients

(2007) I. Elalamy et al.   THROMBOSIS RESEARCH