Article
Radiology, Nuclear Medicine & Medical Imaging
Qiang Cai, Natthaya Triphuridet, Yeqing Zhu, Nan You, Rowena Yip, David F. Yankelevitz, Claudia Henschke
Summary: Bronchiectasis is prevalent in smokers undergoing low-dose CT screening, and the occurrence of respiratory symptoms and acute events increases with the severity of the Early Lung and Cardiac Action Program Bronchiectasis score.
Article
Medicine, General & Internal
Lisa Jungblut, Harry Etienne, Caroline Zellweger, Alessandra Matter, Miriam Patella, Thomas Frauenfelder, Isabelle Opitz
Summary: This pilot study in Switzerland assesses the implementation and performance of low-dose CT lung cancer screening and explores its potential impact on reducing mortality rates. The study enrolls participants meeting specific criteria and uses LDCT scans for assessment. Preliminary results suggest the feasibility of LDCT lung cancer screening in Switzerland.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Eui Jin Hwang, Jin Mo Goo, Hyae Young Kim, Jaeyoun Yi, Yeol Kim
Summary: Elevating the diameter threshold for solid nodules from 6 to 9 mm may lead to a substantial reduction in unnecessary follow-up LDCTs with a small proportion of diagnostic delay of lung cancers.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sung Hyun Yoon, Yong Ju Kim, Kibbeum Doh, Junghoon Kim, Kyung Hee Lee, Kyung Won Lee, Jihang Kim
Summary: This study assessed interobserver agreement in Lung-RADS categorisation of subsolid nodules in low-dose screening CTs, showing higher concordance among experienced thoracic radiologists. Overall, the interobserver agreement was moderate.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mario Silva, Gianluca Milanese, Stefano Sestini, Federica Sabia, Colin Jacobs, Bram van Ginneken, Mathias Prokop, Cornelia M. Schaefer-Prokop, Alfonso Marchiano, Nicola Sverzellati, Ugo Pastorino
Summary: This study analyzed the distribution of Lung-RADS v1.1 volumetric categories and lung cancer outcomes within 3 years in order to explore personalized algorithm for lung cancer screening. It found that nodule volume was a strong predictor of lung cancer risk and personalized screening algorithm by increased interval seems feasible in 80% of NLST eligible participants.
EUROPEAN RADIOLOGY
(2021)
Article
Engineering, Biomedical
Stojan Trajanovski, Dimitrios Mavroeidis, Christine Leon Swisher, Binyam Gebrekidan Gebre, Bastiaan S. Veeling, Rafael Wiemker, Tobias Klinder, Amir Tahmasebi, Shawn M. Regis, Christoph Wald, Brady J. McKee, Sebastian Flacke, Heber MacMahon, Homer Pien
Summary: This study utilized a deep learning framework along with multiple lung cancer screening datasets to accurately estimate malignancy risk of lung cancer. The model demonstrated excellent performance in terms of generalization, accuracy, and stability, outperforming state-of-the-art models and achieving comparable results to radiologists in assessing cancer risk at a patient level.
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
(2021)
Review
Oncology
Marleen Vonder, Monique D. Dorrius, Rozemarijn Vliegenthart
Summary: This review provides an overview of the evolution of CT protocols in lung cancer screening, emphasizing the reduction of radiation dose and application of dose reduction techniques. Efforts by international radiology organizations to streamline CT data acquisition and image quality assurance are highlighted, along with future perspectives and recommendations for CT lung cancer screening protocols.
TRANSLATIONAL LUNG CANCER RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyungjin Kim, Hyae Young Kim, Jin Mo Goo, Yeol Kim
Summary: The study validated and compared the performance of the Brock model and Lung-RADS in detecting nodules on baseline CT scans. Both models showed high discrimination but poor calibration performance. The study concluded that Lung-RADS, with visual assessment-based categories, has similar diagnostic performance to the Brock model.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
Jorge Diaz-Alvarez, Patricia Roiz, Luis Gorospe, Ana Ayala, Sergio Perez-Pinto, Javier Martinez-Sanz, Matilde Sanchez-Conde, Jose L. Casado, Maria J. Perez-Elias, Ana Moreno, Raquel Ron, Maria J. Vivancos, Pilar Vizcarra, Santiago Moreno, Sergio Serrano-Villar
Summary: In this pilot program, the prevalence of lung cancer among people with HIV screened using LDCT was 3.6%, and the number needed to screen to detect one case of lung cancer was 28. While data from additional cohorts with longitudinal measurements are needed, people with HIV are a target population for lung cancer screening with LDCT.
Article
Radiology, Nuclear Medicine & Medical Imaging
Bruno Hochhegger, Andres Pelaez, Tiago Machuca, Tan-Lucien Mohammed, Pratik Patel, Matheus Zanon, Felipe Torres, Stephan Altmayer, Douglas Zaione Nascimento
Summary: This study compared the CT imaging findings of COVID-19 in lung transplant recipients and non-transplanted controls. The results showed significant differences in imaging findings and lung density patterns between the two groups, with lung transplant recipients exhibiting more severe parenchymal abnormalities.
EUROPEAN RADIOLOGY
(2023)
Article
Oncology
Anton Schreuder, Onno M. Mets, Cornelia M. Schaefer-Prokop, Colin Jacobs, Mathias Prokop
Summary: The study suggests that conducting three additional annual CT screening rounds in the National Lung Screening Trial may lead to substantial reduction in lung cancer mortality, with earlier diagnosis of lung cancer patients compared to original screening methods.
Review
Medicine, General & Internal
Scott J. Adams, Emily Stone, David R. Baldwin, Rozemarijn Vliegenthart, Pyng Lee, Florian J. Fintelmann
Summary: Randomised controlled trials have shown that low-dose CT lung cancer screening reduces mortality compared with chest radiography or no screening. However, uncertainties remain about optimizing clinical and cost effectiveness. This Review provides an international perspective on lung cancer screening, covering clinical trials, identification of individuals who benefit, management of screen-detected findings, smoking cessation interventions, cost-effectiveness, artificial intelligence and biomarkers, and challenges and opportunities in implementation.
Article
Oncology
Jingmin Yuan, Yan Sun, Ke Wang, Zhiyi Wang, Duo Li, Meng Fan, Xiang Bu, Mingwei Chen, Hui Ren
Summary: This study provides the optimal lung cancer screening strategy in China based on cost-effectiveness analysis. The results suggest that starting screening at 50 years old can achieve the maximum net health benefits for heavy smokers.
CANCER PREVENTION RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yoshimi Anzai, Chun-Pin Chang, Kerry Rowe, John Snyder, Vikrant Deshmukh, Michael Newman, Alison Fraser, Ken Smith, Ankita Date, Carlos Galvao, Marcus Monroe, Mia Hashibe
Summary: This study found that surveillance imaging in patients with head and neck cancer is associated with lower mortality. Specifically, for regionalized or distant squamous cell carcinoma, surveillance imaging was associated with a lower risk of death.
Article
Medicine, General & Internal
Michael G. Milligan, Inga T. Lennes, Saif Hawari, Melin J. Khandekar, Yolonda Colson, Jo-Anne O. Shepard, Angela Frank, Lecia Sequist, Henning Willers, Florence K. Keane
Summary: This study conducted in a lung nodule and lung cancer screening clinic aimed to evaluate the role of stereotactic body radiation therapy among patients enrolled in a lung cancer screening program. The findings revealed that one in four patients with screen-detected pulmonary nodules requiring intervention were treated with stereotactic body radiation therapy, highlighting the importance of radiation oncologists in the multidisciplinary management of pulmonary nodules.
Article
Clinical Neurology
M. Lang, M. D. Li, K. Z. Jiang, B. C. Yoon, D. P. Mendoza, E. J. Flores, S. P. Rincon, W. A. Mehan Jr, J. Conklin, S. Y. Huang, A. L. Lang, D. M. Giao, T. M. Leslie-Mazwi, J. Kalpathy-Cramer, B. P. Little, K. Buch
Summary: This study investigated the relationship between the severity of chest imaging findings in COVID-19 patients and the risk of acute neuroimaging findings. Results showed that patients with acute neuroimaging findings had significantly longer hospitalization, higher rates of intensive care unit admission, and more patients requiring intubation compared to those without acute neuroimaging findings.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2021)
Letter
Critical Care Medicine
Min Lang, Tristan Yeung, Jo-Anne O. Shepard, Amita Sharma, Milena Petranovic, Efren J. Flores, Theresa C. McLoud, Avik Som, Sanjay Saini, Anand M. Prabhakar, Marc D. Succi, Brent P. Little
Letter
Public, Environmental & Occupational Health
Austin Snyder, Sean Jang, Ilana S. Nazari, Avik Som, Efren J. Flores, Marc D. Succi, Brent P. Little
Summary: The COVID-19 pandemic has caused delays in cancer diagnosis, partly due to the postponement of cancer screening. During the pandemic, public attention to cancer screening significantly decreased, leading to up to a 76% drop in search volume for related terms. Maintaining awareness of cancer screening during future public health crises may help reduce delays in cancer diagnosis.
JOURNAL OF MEDICAL SCREENING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Juan Carlos Villa Camacho, Miguel A. Pena, Efren J. Flores, Brent P. Little, Yasha Parikh, Anand K. Narayan, Randy C. Miles
Summary: This study evaluated the readability of breast cancer online patient educational materials (OPEM) written in Spanish compared to equivalent English-language OPEM. The Spanish-language OPEM were found to be written at a significantly lower grade reading level than the English-language versions, and were more likely to meet AMA recommendations.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Efren J. Flores, Anand K. Narayan
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
K. Anand Narayan, W. Pamela Schaefer, Dania Daye, Carmen Alvarez, B. Daniel Chonde, C. Theresa McLoud, J. Efren Flores, A. James Brink
Summary: The article discusses the importance of addressing systemic racism, racial/ethnic disparities, and improving diversity and inclusion in radiology highlighted by the COVID-19 pandemic and deaths of Black individuals. It provides a framework and practical tips for creating a comprehensive, institutionally aligned radiology DEI committee based on the experience of an integrated, academic northeastern radiology department.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Efren J. Flores, Kelly E. Irwin, Elyse R. Park, Ruth C. Carlos
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Anand K. Narayan, Divya N. Chowdhry, Florian J. Fintelmann, Brent P. Little, Jo-Anne O. Shepard, Efren J. Flores
Summary: This study evaluated the impact of revised USPSTF guidelines on racial and ethnic disparities in lung cancer screening eligibility, finding that the revised guidelines may perpetuate disparities in lung cancer screening.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Andrew B. Ross, Maria Daniela Martin Rother, Randy C. Miles, Efren J. Flores, Newman Kwame Boakye-Ansa, Corey Brown, Anand K. Narayan
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Anand K. Narayan
AMERICAN JOURNAL OF ROENTGENOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Arissa J. Milton, Efren J. Flores, Eden F. Charles, Mai A. Elezaby, Earlise C. Ward, Christoph I. Lee, Ryan W. Woods, Maria D. Martin Rother, Roberta M. Strigel, Anand K. Narayan
Summary: Community-based participatory research (CBPR) is a collaborative process that involves all partners in the research process and recognizes the unique strengths of each community member. It aims to combine knowledge and action for social change and improve community health. CBPR can be applied in radiology to address issues such as improving imaging quality, secondary prevention, technology access barriers, and increasing diversity in research participation.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Priscilla J. Slanetz, Somiah Almeky, Anand K. Narayan, Jacqueline A. Bello
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
B. Daniel Chonde, Ali Pourvaziri, Joy Williams, Jennifer McGowan, Margo Moskos, Carmen Alvarez, K. Anand Narayan, Dania Daye, J. Efren Flores, D. Marc Succi
Summary: The study aimed to evaluate the implementation of a web application providing multilingual radiology examination instructions. By utilizing artificial intelligence for multilingual audio instructions, the strain on medical interpreters was reduced, variability in examination length was improved, resulting in a more reliable average examination time.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Anand K. Narayan, Ali Pourvaziri, Diego B. Lopez, Randy C. Miles, Avinash Kambadakone, Efren J. Flores
Summary: The study aimed to estimate the proportion of patients who have undergone CT examinations but have not received recommended colorectal cancer (CRC) screening. The results showed that nearly 1 out of 3 patients who had CT scans did not receive CRC screening.
CURRENT PROBLEMS IN DIAGNOSTIC RADIOLOGY
(2021)