Editorial Material
Multidisciplinary Sciences
Shaunak Deota, Satchidananda Panda
Summary: By combining calorie restriction, fasting, and regulating circadian rhythms, mice can achieve a long and healthy life.
Article
Oncology
Ozgul Karayurt, Zeynep Deveci, Sibel Eyigor, Menekse Ozgur Inbat
Summary: The Quality of Life Measure for Limb Lymphedema-Arm was successfully adapted into Turkish and proven to be valid and reliable in the Turkish population. This questionnaire can be used to evaluate the quality of life in patients with BCRL, providing a valuable tool for clinical settings and studies.
Review
Biochemistry & Molecular Biology
Ekaterina Sergeeva, Tatiana Ruksha, Yulia Fefelova
Summary: The risk of malignant tumor development is increasing worldwide, with obesity being a known risk factor. Obesity is associated with metabolic alterations that promote cancerogenesis, including increased levels of estrogens, chronic inflammation, and hypoxia. Calorie restriction has been shown to improve the condition of patients with various diseases by influencing metabolism, hormone levels, and cell processes. It can regulate signal cascades that affect cancer cell proliferation, migration, survival, apoptosis, and response to chemotherapy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Alessandro de Sire, Nicola Fusco, Elham Sajjadi, Lorenzo Lippi, Carlo Cisari, Marco Invernizzi
Summary: This study evaluated the safety and tolerability of an instantly adjustable IC device in BCRL patients and found it to be effective in reducing BCRL volume significantly and decreasing IC application time, suggesting that IC could be considered as a safe, well-tolerated, and effective tool in the rehabilitative management of BCRL patients.
APPLIED SCIENCES-BASEL
(2021)
Article
Oncology
Michelle J. Naughton, Heshan Liu, Drew K. Seisler, Jennifer Le-Rademacher, Jane M. Armer, Jill M. Oliveri, Jeffrey A. Sloan, Karen Hock, Michael Schwartz, Gary Unzeitig, Marianne Melnik, Lisa D. Yee, Gini F. Fleming, John R. Taylor, Charles Loprinzi, Electra D. Paskett
Summary: The study found no significant differences between two interventions in preventing lymphedema or improving HRQOL. However, African American patients reported more severe lymphedema symptoms but better emotional functioning compared to patients of other races or ethnicities. Factors like younger age, performance status, number of positive lymph nodes, education level, chemotherapy, and type of node dissection were associated with lower HRQOL during the intervention.
Article
Oncology
Linda Koehler, Lauren Elyse Penz, Florence John, Ashley Stenzel, Patricia Jewett, Deanna Teoh, Anne Blaes, Colleen Rivard, Rachel Vogel
Summary: The aim of this study was to compare the differences in function, quality of life, body image, and distress levels between gynecologic cancer survivors with and without lymphedema symptoms, and determine the number of individuals who received rehabilitation treatment following treatment for gynecological malignancy. The findings showed that participants in the symptomatic group had lower quality of life, lower function scores, and greater cancer-related distress, with higher rates of clinically significant levels of distress. These results remained largely consistent in multivariable models.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Oncology
Michelle Coriddi, Leslie Kim, Leslie McGrath, Elizabeth Encarnacion, Nicholas Brereton, Yin Shen, Andrea V. Barrio, Babak Mehrara, Joseph H. Dayan
Summary: The LLIS and ULL27 are highly accurate, sensitive, and specific for detecting lymphedema in breast cancer patients who have undergone ALND. These questionnaires can effectively diagnose lymphedema, potentially reducing the need for frequent clinic visits and time-consuming measurements.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Surgery
Hong Bae Jeon, Ji Hyuk Jung, Sang Hee Im, Yong Bae Kim, Jee Suk Chang, Seung Yong Song, Dae Hyun Lew, Tai Suk Roh, Won Jai Lee, Dong Won Lee
Summary: This study aimed to investigate the impact of immediate breast reconstruction on the risk of breast cancer-related lymphedema. The results showed that immediate breast reconstruction can reduce the incidence of lymphedema.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Oncology
Cansu Hazal Yanardag, Gulsum Nihal Curuk, Ozgul Karayurt
Summary: This study examined the effects of selfcare and selected factors on the quality of life in women with breast cancer-related lymphedema. Data from 101 women were analyzed, and the results showed that selfcare, time elapsed after breast cancer diagnosis, and time elapsed after lymphedema diagnosis significantly impacted quality of life. Education, support, and regular evaluation of patients' quality of life should be provided.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Nutrition & Dietetics
Emiliana Giacomello, Luana Toniolo
Summary: Aging is a biological process influenced by multiple cellular mechanisms leading to functional decline. The growth of the elderly population and their susceptibility to diseases drive the search for anti-aging interventions, with calorie restriction identified as an effective approach.
Article
Multidisciplinary Sciences
Libia Alejandra Garcia-Flores, Cara L. Green, Sharon E. Mitchell, Daniel E. L. Promislow, David Lusseau, Alex Douglas, John R. Speakman
Summary: Caloric restriction affects the metabolome in a tissue-specific manner, with only a small number of common metabolic features responding in the same way across all tissues. The top modulated pathways were related to biosynthesis and degradation processes, suggesting each tissue has its own unique way of coping with reduced energy intake, supporting the clean cupboards hypothesis over the disposable soma interpretation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Oncology
Yawei Lin, Chao Wu, Chunyan He, Jiaran Yan, Yi Chen, Li Gao, Rongrong Liu, Baohua Cao
Summary: The study aimed to compare the effects of three exercise programs on lymphedema, pain, and quality of life in breast cancer patients, as well as explore the impact of intensive follow-up on the outcomes. The results showed that JME + PRE had the best effect on improving quality of life and preventing lymphedema, while JME + AE had the best effect in relieving pain. Furthermore, long-term and planned monitoring and follow-up were also found to be important.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Genetics & Heredity
Meden F. Isaac-Lam, Kelly M. DeMichael
Summary: Calorie restriction is a safe way to extend lifespan and decrease the risk of age-related diseases. It can alter metabolism, enhance health characteristics, and reduce the occurrence of cancer risk factors.
JOURNAL OF MOLECULAR MEDICINE-JMM
(2022)
Article
Medicine, General & Internal
Julie Bruce, Bruno Mazuquin, Alastair Canaway, Anower Hossain, Esther Williamson, Pankaj Mistry, Ranjit Lall, Stavros Petrou, Sarah E. Lamb, Sophie Rees, Emma Padfield, Raghavan Vidya, Alastair M. Thompson
Summary: The study evaluated the impact of a structured exercise programme on functional and health-related quality of life outcomes for women at high risk of upper limb disability after breast cancer surgery. The results showed that the exercise programme significantly improved upper limb function and reduced pain for patients.
BMJ-BRITISH MEDICAL JOURNAL
(2021)
Article
Oncology
Fatima Cardoso, Amelia McCartney, Antonio Ponti, Lorenza Marotti, Conny Vrieling, Alexandru Eniu, Berta Sousa, Carla Ripamonti, Luzia Travado, Sabine Spitz, Eva Jolly, Giuseppe Curigliano, Frederique Penault-Llorca, Frederic Lecouvet, Isabel T. Rubio, Laura Biganzoli
Summary: The European Society of Breast Cancer Specialists and the Advanced Breast Cancer Global Alliance have developed the first set of quality indicators for metastatic breast cancer (MBC) with the aim of ensuring high-quality care and adherence to guidelines in breast cancer centers.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Plant Sciences
Javad Heshmati, Ashraf Moini, Mahdi Sepidarkish, Mojgan Morvaridzadeh, Masoud Salehi, Andriko Palmowski, Maryam Farid Mojtahedi, Farzad Shidfar
Summary: The study found that using curcumin in PCOS patients can effectively improve blood sugar and androgen levels, and is safe and reliable. Longer trials with different dosages are needed to confirm these findings.
Article
Oncology
Safa Najafi, Maryam Ansari, Vahid Kaveh, Shahpar Haghighat
Summary: This study compared the efficacy and side effects of single dose and repeated dose GCF treatments in breast cancer patients, showing no significant differences in hematologic parameters and treatment processes between single dose PDL and repeated PDG injections, with fewer side effects reported with PDL.
Article
Computer Science, Software Engineering
Anaram Yaghoobi Notash, Peyman Bayat, Shahpar Haghighat, Ali Yaghoobi Notash
Summary: The study introduces a horizontal-vertical image scanning (HVIS) tool and an evolutionary ensemble feature selection learning (EEFSL) for measuring the arm volume of breast cancer patients with arm lymphedema, indicating that the proposed method is reliable and effective.
CONCURRENCY AND COMPUTATION-PRACTICE & EXPERIENCE
(2022)
Article
Oncology
Ali Saneei Totmaj, Shahpar Haghighat, Shapour Jaberzadeh, Mehraban Navaei, Saeideh Vafa, Leila Janani, Hadi Emamat, Zahra Salehi, Maryam Izad, Mitra Zarrati
Summary: The study found that synbiotic supplementation combined with a low-calorie diet intervention significantly reduced arm lymphedema volume in patients with BCRL and had a positive effect on increasing serum levels of TGF-β, IL-10, and adiponectin.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2022)
Article
Multidisciplinary Sciences
Akram Yazdani, Mehdi Yaseri, Shahpar Haghighat, Ahmad Kaviani, Hojjat Zeraati
Summary: Quantile regression model is a flexible approach for analyzing censored data, which can provide more intuitive interpretation of covariate effects by modeling different quantiles. In the study of breast cancer survival time, tumor grade and disease stage were identified as significant factors affecting the 20th percentile of survival time.
SCIENTIFIC REPORTS
(2021)
Article
Health Policy & Services
Solmaz Roshandel, Minoor Lamyian, Seyed Ali Azin, Shahpar Haghighat, Eesa Mohammadi
Summary: This study aims to develop and validate a guideline on the sexual and reproductive health of breast cancer survivors in Iran. The guideline will be developed based on survivors' specific needs and culture, with potential to significantly improve survivors' quality of life.
HEALTH RESEARCH POLICY AND SYSTEMS
(2021)
Article
Medicine, Research & Experimental
S. Najafi, Z. Heidarali, M. Rajabi, Z. Omidi, F. Zayeri, M. Salehi, S. Haghighat
Summary: The study found that 300 mg of lithium taken once daily for 5 days may not effectively prevent CIPN in breast cancer patients. Symptoms of CIPN worsened in the first 3 months of treatment but improved by the ninth month.
Article
Medical Informatics
Anaram Yaghoobi Notash, Aidin Yaghoobi Notash, Zahra Omidi, Shahpar Haghighat
Summary: This study aims to predict the risk of lymphedema and identify its factors by selecting appropriate models. The Support Vector Machine algorithm was found to be the superior model for predicting lymphedema, and significant features affecting lymphedema were identified. This approach can accurately predict lymphedema and help clinics choose suitable preventive and therapeutic methods.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Article
Oncology
Mahsa Raji Lahiji, Akram Sajadian, Shahpar Haghighat, Mitra Zarrati, Homa Dareini, Mahtab Raji Lahiji, Elham Razmpoosh
Summary: This study aimed to investigate the effects of nutrition counseling and logotherapy on the psychological status, quality of life, and dietary intake of breast cancer survivors. The results indicated that the combination of nutrition counseling and logotherapy significantly improved anxiety and depression, as well as reduced energy, carbohydrate, and fat intake.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Public, Environmental & Occupational Health
Afsaneh Fendereski, Ebrahim Hajizadeh, Shahpar Haghighat, Aliakbar Rasekhi
Summary: This study compared long-term disease-free survival of non-metastatic breast cancer patients based on different molecular subtypes. The results showed that HR+/HER2- subtype had the best prognosis, while HR-/HER2+ subtype had the worst prognosis.
Article
Psychology, Multidisciplinary
Roghieh Nooripour, Simin Hosseinian, Nikzad Ghanbari, Shahpar Haghighat, Joshua J. Matacotta, Maria Luisa Gasparri
Summary: This study assessed the application of the Satisfaction with Life Scale (SWLS) among Iranian women with breast cancer. The results showed that the scale has good reliability and validity in this population, making it a reliable tool for assessing life satisfaction.
CURRENT PSYCHOLOGY
(2023)
Review
Medicine, Research & Experimental
Malihe Khoramdad, Masoud Solaymani-Dodaran, Ali Kabir, Neda Ghahremanzadeh, Esmat-o-Sadat Hashemi, Noushin Fahimfar, Zahra Omidi, Mohammad Ali Mansournia, Asiie Olfatbakh, Hamid Salehiniya, Shahpar Haghighat
Summary: This study aimed to identify risk factors for breast cancer in Iranian women. The results showed that obesity, age at marriage, second-hand smoking, smoking, history of abortion, and oral contraceptive use were modifiable risk factors associated with increased breast cancer risk. Additionally, non-modifiable risk factors such as history of radiation exposure, family history of breast cancer, and early age at menarche were also associated with increased risk.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2022)
Article
Oncology
Akram Yazdani, Shahpar Haghighat
Summary: This study aimed to investigate the role of prognostic factors on disease-free survival in breast cancer using a quantile regression model. The results showed that tumor size, grade, and lymph node ratio were closely related to disease-free survival in breast cancer.
BREAST CANCER-BASIC AND CLINICAL RESEARCH
(2022)
Review
Medicine, General & Internal
Zahra Omidi, Maryam Koosha, Najme Nazeri, Nasim Khosravi, Sheida Zolfaghari, Shahpar Haghighat
Summary: This study investigated the status of breast cancer preventive behaviors and screening indicators among Iranian women in the past 15 years. The findings revealed low rates of breast self-examination and mammography among Iranian women, and educational interventions were effective in improving screening behaviors. The study suggests the need for a cost-effective screening program and proper educational methods for increasing women's awareness.
JOURNAL OF RESEARCH IN MEDICAL SCIENCES
(2022)
Article
Immunology
Nasim Khosravi, Erik D. Hanson, Vahid Farajivafa, William S. Evans, Jordan T. Lee, Eli Danson, Chad W. Wagoner, Elizabeth P. Harrell, Stephanie A. Sullivan, Kirsten A. Nyrop, Hyman B. Muss, David B. Bartlett, Brian C. Jensen, Shahpar Haghighat, Mahdieh Molanouri Shamsi, Claudio L. Battaglini
Summary: Exercise training can reduce pro-inflammatory cytokine production in monocytes of breast cancer survivors, especially IL-1B. Acute exercise downregulates the expression of TLR2 and TLR4 on monocytes, but this effect is not sustained over the course of training.
BRAIN, BEHAVIOR, & IMMUNITY - HEALTH
(2021)
