4.2 Article

Antibacterial effect of chlorhexidine-cetrimide combination, Salvia officinalis plant extract and octenidine in comparison with conventional endodontic irrigants

Journal

DENTAL MATERIALS JOURNAL
Volume 35, Issue 5, Pages 736-741

Publisher

JAPANESE SOC DENTAL MATERIALS DEVICES
DOI: 10.4012/dmj.2015-159

Keywords

Cetrimide; Chlorhexidine; Enterococcus faecalis; Octenidine hydrochloride; Salvia officinalis

Funding

  1. Selcuk University, Scientific Research Project Coordination Center

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The aim of the present study was to compare the antimicrobial effect of sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), a CHX/cetrimide solution (CHX+CTR), octenidine hydrochloride (OCT) and Salvia officinalis plant extract against Enterococcus faecalis. Seventy decoronated single -rooted human teeth were infected and divided into 6 test (n,=10) and 2 control groups (n=5) (negative, sterile samples and positive, infected samples). Following irrigants were then applied to test groups: 2.5% NaOCl, 5.25% NaOCl, CHX, CHX+CTR, S. officinalis extract and OCT. The dentin chips were obtained from inner root canal walls and analyzed by counting the number of colony forming units (CFU). The 2.5% NaOCl, 5.25% NaOCl, CHX and OCT groups presented no bacterial growth (CFU=0). S. officinalis and CHX+CTR groups reduced the number of E. faecalis cells but could not eliminate all. OCT may have potential as an endodontic irrigant in treatment of infected root canals.

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