Virtual controls as an alternative to randomized controlled trials for assessing efficacy of interventions

In Vitro and in Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2

(2019) Samer Haidar et al.   MOLECULES

Using Electronic Health Records to Derive Control Arms for Early Phase Single‐Arm Lung Cancer Trials: Proof‐of‐Concept in Randomized Controlled Trials

(2019) Gillis Carrigan et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The use of a predictive statistical model to make a virtual control arm for a clinical trial

(2019) Jeffrey M. Switchenko et al.   PLoS One

Recruitment effort and costs from a multi-center randomized controlled trial for treating depression in type 2 diabetes

(2019) Barbara A. Myers et al.   Trials

Ethical principles and placebo-controlled trials – interpretation and implementation of the Declaration of Helsinki’s placebo paragraph in medical research

(2018) Antonia-Sophie Skierka et al.   BMC Medical Ethics

Reproducibility of clinical research in critical care: a scoping review

(2018) Daniel J. Niven et al.   BMC Medicine

An Algorithm for Creating Virtual Controls Using Integrated and Harmonized Longitudinal Data

(2018) William B. Hansen et al.   EVALUATION & THE HEALTH PROFESSIONS

Quasi-experimental study designs series—paper 4: uses and value

(2017) Till Bärnighausen et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Comparison of Propensity Score Methods and Covariate Adjustment

(2017) Markus C. Elze et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

“Threshold-crossing”: A Useful Way to Establish the Counterfactual in Clinical Trials?

(2016) H-G Eichler et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Randomized controlled trial: the gold standard or an unobtainable fallacy?

(2015) Lars Bondemark et al.   EUROPEAN JOURNAL OF ORTHODONTICS

Withdrawal Symptoms after Selective Serotonin Reuptake Inhibitor Discontinuation: A Systematic Review

(2015) Giovanni A. Fava et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Trauma in silico: Individual-specific mathematical models and virtual clinical populations

(2015) David Brown et al.   Science Translational Medicine

Generation of “Virtual” Control Groups for Single Arm Prostate Cancer Adjuvant Trials

(2014) Zhenyu Jia et al.   PLoS One

Discriminating Survival Outcomes in Patients with Glioblastoma Using a Simulation-Based, Patient-Specific Response Metric

(2013) Maxwell Lewis Neal et al.   PLoS One

Volunteer Bias in Recruitment, Retention, and Blood Sample Donation in a Randomised Controlled Trial Involving Mothers and Their Children at Six Months and Two Years: A Longitudinal Analysis

(2013) Sue Jordan et al.   PLoS One

Equipoise should be amended, not abandoned

(2011) Rieke van der Graaf et al.   Clinical Trials

Predictive value of the Seattle Heart Failure Model in patients undergoing left ventricular assist device placement

(2010) Eric S. Ketchum et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Child/Adolescent Anxiety Multimodal Study (CAMS): rationale, design, and methods

(2010) Scott N Compton et al.   Child and Adolescent Psychiatry and Mental Health

The Treatment for Adolescents With Depression Study (TADS): Outcomes Over 1 Year of Naturalistic Follow-Up

(2009)   AMERICAN JOURNAL OF PSYCHIATRY

Strengths and Difficulties Questionnaire Added Value Scores: evaluating effectiveness in child mental health interventions

(2009) Tamsin Ford et al.   BRITISH JOURNAL OF PSYCHIATRY

Observational Studies Analyzed Like Randomized Experiments

(2008) Miguel A. Hernán et al.   EPIDEMIOLOGY

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders – First Revision

(2008) Borwin Bandelow et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY