Isoleucyl-tRNA synthetase mutant based whole-cell biosensor for high-throughput selection of isoleucine overproducers

Improvement of l-Valine Production by Atmospheric and Room Temperature Plasma Mutagenesis and High-Throughput Screening in Corynebacterium glutamicum

(2020) Guoqiang Han et al.   ACS Omega

Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction

(2020) Rongzhen Tian et al.   Nature Communications

Development of a Synthetic 3-Dehydroshikimate Biosensor in Escherichia coli for Metabolite Monitoring and Genetic Screening

(2019) Liangpo Li et al.   ACS Synthetic Biology

Synthetic biology for evolutionary engineering: from perturbation of genotype to acquisition of desired phenotype

(2019) Jina Yang et al.   Biotechnology for Biofuels

Syntrophic co-culture amplification of production phenotype for high-throughput screening of microbial strain libraries

(2019) Tatyana E. Saleski et al.   METABOLIC ENGINEERING

GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli

(2019) Xiaowei Wang et al.   Microbial Cell Factories

Efficient production of trans -4-hydroxy- l -proline from glucose using a new trans -proline 4-hydroxylase in Escherichia coli

(2018) Xing-Chu Wang et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

MACBETH: Multiplex automated Corynebacterium glutamicum base editing method

(2018) Yu Wang et al.   METABOLIC ENGINEERING

Synthetic addiction extends the productive life time of engineeredEscherichia colipopulations

(2018) Peter Rugbjerg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Utilization of rare codon-rich markers for screening amino acid overproducers

(2018) Bo Zheng et al.   Nature Communications

Pathway optimization and key enzyme evolution of N -acetylneuraminate biosynthesis using an in vivo aptazyme-based biosensor

(2017) Peng Yang et al.   METABOLIC ENGINEERING

Fundamental Design Principles for Transcription-Factor-Based Metabolite Biosensors

(2017) Ahmad A. Mannan et al.   ACS Synthetic Biology

Genetic biosensors for small-molecule products: Design and applications in high-throughput screening

(2017) Qingzhuo Wang et al.   Frontiers of Chemical Science and Engineering

Screening of an Escherichia coli promoter library for a phenylalanine biosensor

(2016) Regina Mahr et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Recent advances in amino acid production by microbial cells

(2016) Takashi Hirasawa et al.   CURRENT OPINION IN BIOTECHNOLOGY

Evolving the l-lysine high-producing strain of Escherichia coli using a newly developed high-throughput screening method

(2016) Yan Wang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Discharging tRNAs: a tug of war between translation and detoxification inEscherichia coli

(2016) Irem Avcilar-Kucukgoze et al.   NUCLEIC ACIDS RESEARCH

Evolution of a chimeric aspartate kinase for L-lysine production using a synthetic RNA device

(2015) Junming Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genetically-encoded nanosensor for quantitative monitoring of methionine in bacterial and yeast cells

(2014) Mohd. Mohsin et al.   BIOSENSORS & BIOELECTRONICS

Enhancing the carbon flux and NADPH supply to increase L-isoleucine production in Corynebacterium glutamicum

(2014) Lianghong Yin et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Evolution-guided optimization of biosynthetic pathways

(2014) Srivatsan Raman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A simple and sensitive biosensor strain for detecting toxoflavin using β-galactosidase activity

(2013) Okhee Choi et al.   BIOSENSORS & BIOELECTRONICS

Genetically encoded FRET-based nanosensor for in vivo measurement of leucine

(2013) Mohd Mohsin et al.   BIOSENSORS & BIOELECTRONICS

Synthetic RNA devices to expedite the evolution of metabolite-producing microbes

(2013) Jina Yang et al.   Nature Communications

Structural Diversity and Protein Engineering of the Aminoacyl-tRNA Synthetases

(2012) John J. Perona et al.   BIOCHEMISTRY

The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids

(2012) Nurije Mustafi et al.   METABOLIC ENGINEERING

ECMDB: The E. coli Metabolome Database

(2012) An Chi Guo et al.   NUCLEIC ACIDS RESEARCH

Rational Design of Escherichia coli for l-Isoleucine Production

(2012) Jin Hwan Park et al.   ACS Synthetic Biology

A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level

(2012) Stephan Binder et al.   GENOME BIOLOGY

Lrp of Corynebacterium glutamicum controls expression of the brnFE operon encoding the export system for l-methionine and branched-chain amino acids

(2011) Christian Lange et al.   JOURNAL OF BIOTECHNOLOGY

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

A novel bioluminescent bacterial biosensor using the highly specific oxidative stress-inducible pgi gene

(2008) Javed H. Niazi et al.   BIOSENSORS & BIOELECTRONICS

Misincorporation of amino acid analogues into proteins by biosynthesis

(2008) Kenneth J. Rodgers et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach

(2008) Bryson D Bennett et al.   Nature Protocols