Review
Polymer Science
Vipin Chandra Kalia, Sanjay K. S. Patel, Jung-Kul Lee
Summary: PHA is a biodegradable plastic that can be produced by bacteria in environmental stress conditions. It has similar physicochemical properties to fossil-fuel-based plastics and unique features that make it suitable for medical devices. PHAs can replace traditional plastic materials used in the biomedical sector and has a wide range of applications.
Review
Chemistry, Physical
Radhakrishnan Sreena, Arputharaj Joseph Nathanael
Summary: Biopolymers, obtained from renewable or non-renewable sources, are ideal for creating tailor-made nanoparticles due to their biocompatibility, biodegradability, low toxicity, and low immunogenicity. Biopolymeric nanoparticles can be classified as natural (based on polysaccharides and proteins) or synthetic. They have gained significant interest for biomedical applications such as tissue engineering, drug delivery, imaging, and cancer therapy. Various fabrication strategies can be used to synthesize biopolymeric nanoparticles, including emulsification, ionic gelation, nanoprecipitation, and electrospray drying. This review aims to explore the use of biodegradable biopolymeric nanoparticles in biomedical applications, which has been overlooked in previous reviews. It highlights the use of protein-based (albumin, gelatin, collagen, silk fibroin), polysaccharide-based (chitosan, starch, alginate, dextran), and synthetic (poly lactic acid, poly vinyl alcohol, poly caprolactone) biopolymeric nanoparticles, as well as the fabrication strategies employed. Future perspectives and challenges in utilizing biopolymeric nanoparticles are also discussed.
Article
Engineering, Biomedical
Michal Dziadek, Kinga Dziadek, Kamila Checinska, Barbara Zagrajczuk, Monika Golda-Cepa, Monika Brzychczy-Wloch, Elzbieta Menaszek, Aneta Kopec, Katarzyna Cholewa-Kowalska
Summary: Polymeric and bioactive glass-modified composite films loaded with polyphenols extracted from sage have been successfully developed. The polyphenolic compounds significantly altered material properties and exhibited biological activity. PPh can act as plasticizers for PCL and coupling agents in composite materials, improving mechanical performance.
BIOACTIVE MATERIALS
(2021)
Review
Biochemistry & Molecular Biology
Anna Paradowska-Stolarz, Mieszko Wieckiewicz, Artur Owczarek, Joanna Wezgowiec
Summary: This review focuses on the recent advances in the use of natural polymers in maintaining or restoring oral health, covering various dental specialties and discussing the comparison between natural and synthetic polymers. It also highlights new perspectives, possible future advancements, and challenges that researchers in the field of dental applications of natural polymers may encounter.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Polymer Science
Mohammad Javad Javid-Naderi, Javad Behravan, Negar Karimi-Hajishohreh, Shirin Toosi
Summary: Damage or loss of bone tissue is a major issue affecting human well-being, and tissue engineering is used to recover and regenerate bone fractures and damage. Polymer biomaterials are the most commonly required materials for synthetic bone scaffolds due to their suitable mechanical properties and degradation rates. Synthetic polymers offer advantages in bone replacement because they can be designed and changed easily, and their biocompatibility has been widely accepted in tissue engineering. This article updates on materials and application usage of scaffolds in bone tissue engineering for hard tissue regeneration.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Review
Chemistry, Multidisciplinary
Oystein Arlov, Dominic Rutsche, Maryam Asadi Korayem, Ece Ozturk, Marcy Zenobi-Wong
Summary: Sulfated polysaccharides play central roles in biological functions, and engineered sulfated polysaccharides exhibit novel and augmented biological properties through facilitating interactions with other macromolecules.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Engineering, Environmental
Manik Chandra Biswas, Bodiuzzaman Jony, Pranab Kumar Nandy, Reaz Ahmed Chowdhury, Sudipta Halder, Deepak Kumar, Seeram Ramakrishna, Masud Hassan, Md Ariful Ahsan, Md Enamul Hoque, Muhammad Ali Imam
Summary: Biopolymers have unique tunable characteristics such as biodegradability, biocompatibility, renewability, which are critically important for designing materials for biomedical applications. By changing the polymer components, smart biopolymers can be prepared for more targeted applications, showing a wide range of uses in drug delivery and wound healing, among others.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Review
Pharmacology & Pharmacy
Panyun Mu, Jie Feng, Yimei Hu, Feng Xiong, Xu Ma, Linling Tian
Summary: This article introduces the pathological characteristics of osteoarthritis and the limitations of traditional treatment methods. The combination of cell and biological carrier implantation and the combination of botanical drug extracts and cartilage tissue engineering are new directions for the treatment of osteoarthritis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Applied
Tomasz Machalowski, Joanna Idaszek, Adrian Chlanda, Marcin Heljak, Adam Piasecki, Wojciech Swieszkowski, Teofil Jesionowski
Summary: The study developed chitin-based biocomposites through biomimetic ex vivo deposition of calcium carbonate particles in the hemolymph from the cultivated mollusk Cornu aspersum and chitinous matrix from the marine demosponge Aplysina fistularis. The results showed that the biofunctionalized scaffold had about 4 times higher mechanical resistance and exhibited significant topographical changes, indicating its potential for modifying cell delivery systems in future biomedical applications.
CARBOHYDRATE POLYMERS
(2022)
Review
Biochemistry & Molecular Biology
Isadora C. Carvalho, Herman S. Mansur, Alice G. Leonel, Alexandra A. P. Mansur, Zelia I. P. Lobato
Summary: This review discusses the current progress in designing and developing polysaccharide-based biomaterials for brain tissue repair and regeneration. Polysaccharides have the potential to enhance advanced technologies in this field by interacting with a variety of biomolecules, including glycosaminoglycans and signaling moieties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Biochemistry & Molecular Biology
Muhammad Umar Aslam Khan, Goran M. Stojanovic, Mohd Faizal Bin Abdullah, Alireza Dolatshahi-Pirouz, Hany E. Marei, Nureddin Ashammakhi, Anwarul Hasan
Summary: Tissue engineering is an advanced biomedical approach that utilizes smart hydrogels to repair and regenerate damaged tissues, treating patients with lost or failed organs or tissues. These hydrogels offer controllable properties, such as tunable mechanical characteristics and biocompatibility, making them ideal for tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Polymer Science
Sabrina Kopf, Dan Akesson, Mikael Skrifvars
Summary: Polyhydroxyalkanoates (PHAs) have great potential in biomedical applications, especially tissue engineering, due to their superior biocompatibility and biodegradability. Textile fiber-based tissue engineering scaffolds can mimic the properties of native tissues, and combining them with PHAs can improve performance. However, the complex crystallization behavior of PHAs and the resulting spinning procedures are still challenging. Additionally, the biomedical application of PHAs is hindered by insufficient polymer purity.
Review
Chemistry, Multidisciplinary
Federico Fontana, Fabrizio Gelain
Summary: The advent of supramolecular biopolymers has brought promising opportunities for tissue engineering, due to their tailorability, absence of toxic byproducts, and better mimicry of extracellular matrix nanotopography and mechanical properties. However, there is still a lack of understanding of their properties at meso- and macroscales. In this review, molecular modeling approaches are discussed, highlighting their advantages and limitations in representing and transferring the properties of supramolecular biopolymers.
NANOTECHNOLOGY REVIEWS
(2022)
Review
Polymer Science
Mattia Bartoli, Erik Piatti, Alberto Tagliaferro
Summary: The development of new scaffolds and materials for tissue engineering is a wide and open realm of material science. Among solutions, the use of biopolymers represents a particularly interesting area of study due to their great chemical complexity that enables creation of specific molecular architectures. However, biopolymers do not exhibit the properties required for direct application in tissue repair-such as mechanical and electrical properties-but they do show very attractive chemical functionalities which are difficult to produce through in vitro synthesis. The combination of biopolymers with nanostructured carbon fillers could represent a robust solution to enhance composite properties, producing composites with new and unique features, particularly relating to electronic conduction. In this paper, we provide a review of the field of carbonaceous nanostructure-containing biopolymer composites, limiting our investigation to tissue-engineering applications, and providing a complete overview of the recent and most outstanding achievements.
Review
Biochemistry & Molecular Biology
Aayushi Randhawa, Sayan Deb Dutta, Keya Ganguly, Dinesh K. Patel, Tejal Patil, Ki-Taek Lim
Summary: Photopolymerization is the process of converting liquid resin into solid structures using specific wavelengths of light. In recent years, photopolymerization-based 3D printing has gained attention for constructing tissue-specific structures. However, the lack of suitable bio-based photopolymers, effective crosslinking strategies, and optimal printing conditions hinder the widespread application of 3D printed materials.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Chemistry, Applied
Chitra Kumar, Abbasriyaludeen Abdul Raheem, Ramesh Mohan, Ramasamy Shanmugam, Chandrasekar Praveen
Summary: This study constructed three new dipolar organic dyes and investigated the impact of structural variation on their photophysical and electrochemical properties. The results indicate that increasing donor size in DSSCs can enhance photovoltaic performance, with electrochemical impedence analysis confirming this finding.
Article
Chemistry, Physical
P. P. Kannan, N. K. Karthick, T. Sangeetha, R. Shanmugam, A. Elangovan, G. Arivazhagan
Summary: FTIR spectral studies revealed specific interactions between methyl cellosolve and acetonitrile in binary solutions, forming different types of complexes. Among them, the 2:4 (AN:MCS) complex is the most stable based on interaction energies.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Physical
Pandiaraj Sekar, Nithya Murugesh, Ramasamy Shanmugam, Shanmugam Senthil Kumar, Stefano Agnoli, Narendraraj Chandran, Seenuvasan Vedachalam, Ramasamy Karvembu
Summary: In this study, a NiCo2O4-P-COP-based electrocatalyst was successfully prepared, exhibiting excellent oxygen reduction, oxygen evolution, and hydrogen evolution reaction performance. By immobilizing the phosphazene-based covalent organic polymer with NiCo2O4, efficient catalytic centers were formed, overcoming durability and activity issues of the electrocatalyst.
ACS APPLIED ENERGY MATERIALS
(2021)
Article
Chemistry, Physical
P. Dineshkumar, R. Sahana, R. Shanmugam, A. Elangovan, R. K. Sankaranarayanan, Y. S. Joshi, G. Arivazhagan, C. Kumbharkhane
Summary: This study investigated the hydrogen bonding interactions between AN/DMSO and AcAc using time domain reflectometry studies, revealing the formation of a 1:1 complex and the presence of non-classical hydrogen bonding interactions in the solutions.
CHEMICAL PHYSICS LETTERS
(2022)
Article
Chemistry, Physical
Sanath Kondaveeti, Gi Dae Park, Ramasamy Shanmugam, Raviteja Pagolu, Sanjay K. S. Patel, Aarti Bisht, Dong Rip Kim, Yun Chan Kang, Jung-Kul Lee
Summary: A new enzymatic biofuel cell was developed using conductive metal alloy nanoparticles and carbon cloth as immobilization support. The cell demonstrated higher power generation and acetoin production efficiency compared to previous biofuel cells.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2022)
Article
Electrochemistry
Shuchi Sharma, Ramasamy Shanmugam, Malaya K. Sahoo, G. Ranga Rao
Summary: In this study, metal oxide Gd2O3 was used as a support to enhance the electrocatalytic activity of Pt/C for methanol oxidation reaction. The Gd2O3(PC) showed better surface oxygen exchange and formation of surface -OH groups, resulting in improved activity for the methanol oxidation reaction. Pt-Gd2O3(PC)/C electrocatalysts prepared by microwave-assisted polyol reflux method exhibited 2.8 times higher activity than commercial Pt/C, with good anti-poisoning activity.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
J. A. Prithi, Ramasamy Shanmugam, Malaya K. Sahoo, N. Rajalakshmi, G. Ranga Rao
Summary: The feasibility of using zirconium carbide (ZrC) as a corrosion-resistant support material in platinum electrocatalysts was evaluated for the first time. The results showed that both ZrC and activated ZrC (a-ZrC) exhibited good corrosion resistance properties during carbon corrosion tests, and met the standard targets set by DoE.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Biotechnology & Applied Microbiology
Anurag Kumar, Jinglin Li, Sanath Kondaveeti, Bakul Singh, Ramasamy Shanmugam, Vipin Chandra Kalia, In-Won Kim, Jung-Kul Lee
Summary: This article presents a study on a NAD(+)-dependent xylitol dehydrogenase (AfXDH) from A. flavus, including its enzymatic activity, thermal stability, and application in l-xylulose production.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Deep Lata Singh, Tapan Kumar Ghosh, Vineet Mishra, Shanmugam Ramasamy, Malaya K. Sahoo, Ranga Rao Gangavarapu
Summary: Lanthanides have been found to be useful for the synthesis of nanoporous materials with high coordination environment, which shows great potential in energy storage. By synthesizing lanthanide-based metal-organic frameworks (MOFs), researchers have discovered their excellent electrochemical performance, making them promising for supercapacitor applications.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Physical
T. Sangeetha, R. Sahana, P. Mounica, A. Elangovan, R. Shanmugam, G. Arivazhagan
Summary: In this study, atoms in molecules theory, electrostatic potential surface, and frontier molecular orbital analyses were performed on water multimers and their hydrogen-bonded complexes with pyridine. The results showed that the electron density and Laplacian of electron density at the bond critical points of the hydrogen bonds between water and pyridine were outside the proposed range. Criteria for weak and medium hydrogen bonds were proposed based on literature reports. The backward difference values of the electron density indicated a decrease/increase in the covalent character of the donor O-H bonds upon classical/non-classical hydrogen bonding.
COMPUTATIONAL AND THEORETICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
T. Sangeetha, R. Sahana, P. Mounica, A. Elangovan, R. Shanmugam, G. Arivazhagan
Summary: Natural bond orbital and reduced density gradient isosurface analyses were conducted on water multimers of order n=1-9 and twenty-five Pyridine-water multimer complexes of order n=1-5. The stability of the complexes was found to increase with an increase in the number of water molecules in water multimers.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Pandiaraj Sekar, Punitharaj Vasanthakumar, Ramasamy Shanmugam, Shanmugam Senthil Kumar, Stefano Agnoli, Rajasekharan Jayakumari Deepak, Karthik Murugan, Nattamai Bhuvanesh, Ramasamy Karvembu
Summary: In this study, redox-active riboflavin was incorporated into a metal-organic framework (MOF) using a post-synthetic modification technique. The modified MOF demonstrated enhanced conductivity and served as a multifunctional electrocatalyst for the oxygen evolution reaction, oxygen reduction reaction, and oxidation of 5-hydroxymethylfurfural.
Correction
Chemistry, Physical
Sruthi G., Shakeela K., Shanmugam R., Ranga Rao G.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Materials Science, Multidisciplinary
Abbasriyaludeen Abdul Raheem, Chitra Kumar, Ramasamy Shanmugam, P. Murugan, Chandrasekar Praveen
Summary: The study presents the synthesis of new D-pi-A push-pull chromophores by incorporating TCNQ on the backbone, leading to improved light absorption and device efficiency. The optimized blend with solvent vapour annealing treatment shows enhanced device performance and improved charge transport properties, potentially increasing efficiency further.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Agricultural Engineering
Yinping Xiang, Meiying Jia, Rui Xu, Jialu Xu, Lele He, Haihao Peng, Weimin Sun, Dongbo Wang, Weiping Xiong, Zhaohui Yang
Summary: This study investigated the impact of the non-antibiotic pharmaceutical carbamazepine on antibiotic resistance genes (ARGs) during anaerobic digestion. The results showed that carbamazepine induced the enrichment of ARGs and increased the abundance of bacteria carrying these genes. It also facilitated microbial aggregation and intercellular communication, leading to an increased frequency of ARGs transmission. Moreover, carbamazepine promoted the acquisition of ARGs by pathogens and elevated their overall abundance.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Weixin Zhao, Tianyi Hu, Hao Ma, Dan Li, Qingliang Zhao, Junqiu Jiang, Liangliang Wei
Summary: This review summarizes the effects and potential mechanisms of biochar on microbial behavior in AD systems. The addition of biochar has been found to promote microbial colonization, alleviate stress, provide nutrients, and enhance enzyme activity. Future research directions include targeted design of biochar, in-depth study of microbial mechanisms, and improved models.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Christina Karmann, Anna Magrova, Pavel Jenicek, Jan Bartacek, Vojtech Kouba
Summary: This review assesses nitrogen removal technologies in reject water treatment, highlighting the differences in environmental impacts and economic benefits. Partial nitritation-anammox shows potential for economic benefits and positive environmental outcomes when operated and controlled properly.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Wei-Hao Huang, Ying-Ju Chang, Duu-Jong Lee
Summary: This study modified pinecone biochar with layered double hydroxide (LDH) to enhance its adsorption capacity for heavy metal and phosphate ions. The LDH-biochar showed significantly improved adsorption capacities for Pb2+ and phosphate, and a slight increase for Cu2+ and Co2+. The LDH layer enhanced the adsorption through various mechanisms.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Chao Song, Fanfan Cai, Shuang Yang, Ligong Wang, Guangqing Liu, Chang Chen
Summary: This paper developed a machine learning model to predict the biochemical methane potential during anaerobic digestion. Model analysis identified lignin content, organic loading, and nitrogen content as key attributes for methane production prediction. For feedstocks with high cellulose content, early methane production is lower but can be improved by prolonging digestion time. Moreover, lignin content exceeding a certain value significantly inhibits methane production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sang Min Lee, Ju Young Lee, Ji-Sook Hahn, Seung-Ho Baek
Summary: This study successfully developed an efficient platform strain using Yarrowia lipolytica for the bioconversion of renewable resources into adipic acid, achieving a remarkable increase in production level.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sefkan Kendir, Matthias Franzreb
Summary: This study presents a novel approach using magnetic separation to efficiently harvest freshwater microalgae, Chlorella vulgaris. By combining pH-induced calcium phosphate precipitation with cheap natural magnetite microparticles, harvesting efficiencies up to 98% were achieved in the model medium.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Ishaq Kariim, Ji-Yeon Park, Wajahat Waheed Kazmi, Hulda Swai, In-Gu Lee, Thomas Kivevele
Summary: The impact of reaction temperature, residence time, and ethanol: acetone on the energy compositions and yield enhancement of biocrudes was investigated. The results showed that under appropriate conditions, biocrudes with high energy and low oxygen content can be obtained, indicating a high potential for utilization.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xiyue Zhang, Xiyao Li, Liang Zhang, Yongzhen Peng
Summary: Intermittent aeration is an innovative approach to enhance nitrogen removal in low carbon-to-nitrogen ratio municipal sewage, providing an efficient strategy for the continuous plug-flow AOA process.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xu Yang, Mahmoud Mazarji, Mengtong Li, Aohua Li, Ronghua Li, Zengqiang Zhang, Junting Pan
Summary: This study investigated the impact of magnetite on the nitrogen cycle of pig manure biostabilisation. The addition of magnetite increased N2O emissions and decreased NH3 emissions during composting. It also increased the total nitrogen content but should be considered for its significant increase in N2O emissions in engineering practice.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Ty Shitanaka, Haylee Fujioka, Muzammil Khan, Manpreet Kaur, Zhi-Yan Du, Samir Kumar Khanal
Summary: The market value of microalgae has exponentially increased in the past two decades, thanks to their applications in various industries. However, the supply of high-value microalgal bioproducts is limited due to several factors, and strategies are being explored to overcome these limitations and improve microalgae production, thus increasing the availability of algal-derived bioproducts in the market.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Martin Kerner, Thorsten Wolff, Torsten Brinkmann
Summary: The efficiency of using enriched CO2 from flue gas for large-scale production of green microalgae has been studied. The results show that the use of membrane devices and static mixers can effectively improve the CO2 recovery rate and maintain the suitable pH and temperature during cultivation, achieving a more economical and sustainable microalgae production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rui Ma, Ji Li, Rd Tyagi, Xiaolei Zhang
Summary: This review summarizes the microorganisms capable of using CO2 and CH4 to produce PHAs, illustrating the production process, factors influencing it, and discussing optimization techniques. It identifies the challenges and future prospects for developing economically viable PHAs production using GHGs as a carbon source.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Bing Wang, Peng Zhang, Xu Guo, Xu Bao, Junjie Tian, Guomin Li, Jian Zhang
Summary: The addition of zeolite in the co-composting of chicken manure and straw significantly reduced the emissions of ammonia and N2O, and increased the nitrate content. Zeolite also promoted the abundance of nitrification genes and inhibited the expression of denitrification genes.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rohit Dey, Franziska Ortiz Tena, Song Wang, Josef Martin Messmann, Christian Steinweg, Claudia Thomsen, Clemens Posten, Stefan Leu, Matthias S. Ullrich, Laurenz Thomsen
Summary: This study investigated the operation of a 1000L microalgae-based membrane photobioreactor system for continuous secondary wastewater treatment. The research focused on a green microalgae strain called Desmodesmus sp. The study aimed to understand key trends and optimization strategies by conducting experiments in both summer and winter seasons. The findings showed that maintaining low cell concentrations during periods of light inhibition was beneficial for nutrient uptake rates. Effective strategies for enhancing algae-based wastewater treatment included cell mass recycling and adjusting dilution rates based on light availability.
BIORESOURCE TECHNOLOGY
(2024)