Synthesis of azachalcones, their α-amylase, α-glucosidase inhibitory activities, kinetics, and molecular docking studies

Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies

(2020) Emmanuel Oloruntoba Yeye et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Thiazole Based Carbohydrazide Derivatives as α-Amylase Inhibitor and Their Molecular Docking Study

(2019) Muhammad Taha et al.   HETEROATOM CHEMISTRY

Biscoumarin-1,2,3-triazole hybrids as novel anti-diabetic agents: Design, synthesis, in vitro α-glucosidase inhibition, kinetic, and docking studies

(2019) Mohammad Sadegh Asgari et al.   BIOORGANIC CHEMISTRY

Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking, and kinetic studies

(2019) Shehryar Hameed et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chalcones and bis -chalcones: As potential α -amylase inhibitors; synthesis, in vitro screening, and molecular modelling studies

(2018) Adebayo Tajudeen Bale et al.   BIOORGANIC CHEMISTRY

Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), in vitro, and in silico evaluation

(2018) Momin Khan et al.   BIOORGANIC CHEMISTRY

2ʹ-Aryl and 4ʹ-arylidene substituted pyrazolones: As potential α-amylase inhibitors

(2018) Sahar Yousuf et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities

(2018) Uzma Salar et al.   Medicinal Chemistry

Analogues of xanthones——Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates

(2017) Chao-Yun Cai et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α -glucosidase inhibitory activity, and in silico studies

(2017) Farman Ali et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study

(2017) Muhammad Taha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nicaraven, a Potential Radioprotective Agent, has Very Limited Effects on the Survival of Cancer Cells and the Growth of Established Tumors

(2017) Chen Yan et al.   RADIATION RESEARCH

Reinvestigation of synthesis of halo-substituted 3-phenyl-1-(2-pyridyl)-2-propen-1-ones (azachalcones). A tandem reaction for formation of penta-substituted cyclohexanols

(2017) Chia-Wai Li et al.   TETRAHEDRON

Immediate early gene expression reveals interactions between social and nicotine rewards on brain activity in adolescent male rats

(2016) Ryan M. Bastle et al.   BEHAVIOURAL BRAIN RESEARCH

Synthesis of 6-chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives: Antidiabetic, antioxidant, β -glucuronidase inhibiton and their molecular docking studies

(2016) Muhammad Taha et al.   BIOORGANIC CHEMISTRY

α-Glucosidases and α-1,4-glucan lyases: structures, functions, and physiological actions

(2016) Masayuki Okuyama et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structural Analysis of β-Fructofuranosidase fromXanthophyllomyces dendrorhousReveals Unique Features and the Crucial Role ofN-Glycosylation in Oligomerization and Activity

(2016) Mercedes Ramírez-Escudero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast α-glucosidase

(2015) Huma Niaz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Type 2 diabetes mellitus

(2015) Ralph A. DeFronzo et al.   Nature Reviews Disease Primers

Evaluation of α-glucosidase inhibitory activity of dichloromethane and methanol extracts of Croton bonplandianum Baill

(2015) MN Qaisar et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

β-Cell function in type 2 diabetes

(2014) Ele Ferrannini et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Synthesis, physicochemical properties, antimicrobial and antioxidant studies of pyrazoline derivatives bearing a pyridyl moiety

(2013) Imtiyaz Hussain Lone et al.   MEDICINAL CHEMISTRY RESEARCH

Exploring Pharmacological Significance of Chalcone Scaffold: A Review

(2012) N. K. Sahu et al.   CURRENT MEDICINAL CHEMISTRY

Molecular modeling studies of some substituted chalcone derivatives as cysteine protease inhibitors

(2011) Nitendra K. Sahu et al.   MEDICINAL CHEMISTRY RESEARCH

Natural Products as α-Amylase and α-Glucosidase Inhibitors and their Hypoglycaemic Potential in the Treatment of Diabetes: An Update

(2010) R. Tundis et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY