Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies

Synthesis of novel thiadiazole derivatives as selective COX-2 inhibitors

(2016) Fatma A. Ragab et al.   MedChemComm

Crystal structure of rofecoxib bound to human cyclooxygenase-2

(2016) Benjamin J. Orlando et al.   Acta Crystallographica Section F-Structural Biology Communications

New Coumarin Derivatives as Potent Selective COX-2 Inhibitors: Synthesis, Anti-Inflammatory, QSAR, and Molecular Modeling Studies

(2015) Dina H. Dawood et al.   ARCHIV DER PHARMAZIE

Synthesis and in vitro antiproliferative activity of new 1,3,4-oxadiazole derivatives possessing sulfonamide moiety

(2015) Mahmoud M. Gamal El-Din et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-pot synthesis and in vivo biological evaluation of new pyrimidine privileged scaffolds as potent anti-inflammatory agents

(2015) Santosh S. Undare et al.   RESEARCH ON CHEMICAL INTERMEDIATES

2,5-Diaryl-1,3,4-oxadiazoles as selective COX-2 inhibitors and anti-inflammatory agents

(2015) Jagdeep Grover et al.   RSC Advances

Celecoxib analogs bearing benzofuran moiety as cyclooxygenase-2 inhibitors: Design, synthesis and evaluation as potential anti-inflammatory agents

(2014) Ghaneya Sayed Hassan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel coumarin–benzimidazole derivatives as antioxidants and safer anti-inflammatory agents

(2014) Radha Krishan Arora et al.   Acta Pharmaceutica Sinica B

Synthesis and pharmacological evaluation of N-substituted 2-(2-oxo-2H-chromen-4-yloxy)propanamide as cyclooxygenase inhibitors

(2012) D. Rambabu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New quinazolinone–pyrimidine hybrids: Synthesis, anti-inflammatory, and ulcerogenicity studies

(2012) Safinaz E. Abbas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4-thiadiazolyl)methylthio)methylene)malononitriles

(2011) V. Padmavathi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, pharmacological evaluation and docking studies of coumarin derivatives

(2011) B. Sandhya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel dihydropyrimidines and its pyrazole derivatives: Synthesis and pharmacological screening

(2011) B. Ramesh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 2,5-disubstituted 1,3,4-oxadiazole derivatives with both COX and LOX inhibitory activity

(2011) Mymoona Akhter et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Some Observations on the Base-Catalyzed Cyclocondensation of 2,6-Dihalobenzaldehydes, Ethyl Cyanoacetate, and Thiourea

(2010) Mohamed A. Al-Omar et al.   SYNTHETIC COMMUNICATIONS

Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety

(2009) Mihaela Moise et al.   MOLECULES