Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity

Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives

(2020) Montaser Sh. Shaykoon et al.   BIOORGANIC CHEMISTRY

5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents

(2019) Bahaa G.M. Youssif et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents

(2019) Mohamed Hisham et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities

(2019) Khalid M. Attalah et al.   BIOORGANIC CHEMISTRY

Optimization of pyrrolizine-based Schiff bases with 4-thiazolidinone motif: Design, synthesis and investigation of cytotoxicity and anti-inflammatory potency

(2019) Ahmed M. Shawky et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies

(2018) Hany A.M. El-Sherief et al.   BIOORGANIC CHEMISTRY

Novel pyrrol-2(3 H )-ones and pyridazin-3(2 H )-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors

(2018) Mahmoud S. Abdelbaset et al.   BIOORGANIC CHEMISTRY

Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2- a ]indol-1(2 H )-ones as potential anticancer agents effecting the reactive oxygen species production

(2018) Bahaa G.M. Youssif et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors

(2018) Hany A.M. El-Sherief et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance

(2017) Gao-Feng Zha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of new coumarin–chalcone/NO hybrids of potential biological activity

(2017) Hany A. El-Sherief et al.   MEDICINAL CHEMISTRY RESEARCH

Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-β-Lactmase-1 (NDM-1) Inhibitors

(2016) Le Zhai et al.   ACS Medicinal Chemistry Letters

Ordering of the N-Terminus of Human MDM2 by Small Molecule Inhibitors

(2012) Klaus Michelsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling

(2011) N. H. Kim et al.   Science Signaling

Synthesis of 3-((2,4-dichlorophenoxy)methyl)-1,2,4-triazolo(thiadiazoles and thiadiazines) as anti-inflammatory and molluscicidal agents

(2010) M.F. El Shehry et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Restoring p53 tumor suppressor activity as an anticancer therapeutic strategy

(2010) Jesse D Martinez   Future Oncology

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression

(2008) Samuel Godar et al.   CELL

A Public Health Approach to Winning the War Against Cancer

(2008) T. R. Frieden et al.   ONCOLOGIST