Fusion peptide engineered “statically-versatile” titanium implant simultaneously enhancing anti-infection, vascularization and osseointegration

Mechanistic Insights and Rational Design of a Versatile Surface with Cells/Bacteria Recognition Capability via Orientated Fusion Peptides

(2019) Lin Wang et al.   Advanced Science

Design and synthesis of biocompatible, hemocompatible and highly selective antimicrobial cationic peptidopolysaccharides via click chemistry

(2019) Yun Chen et al.   BIOMACROMOLECULES

HHC-36 antimicrobial peptide loading on silk fibroin (SF)/hydroxyapatite (HA) nanofibrous-coated titanium for the enhancement of osteoblast and bactericidal functions

(2019) Nastaran Abbasizadeh et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens

(2019) Zhanyi Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Orthopedic Implant-Associated Infection by Multidrug Resistant Enterobacteriaceae

(2019) Bernadette G. Pfang et al.   Journal of Clinical Medicine

Dual-Functional Implants with Antibacterial and Osteointegration-Promoting Performances

(2019) Yujie Sun et al.   ACS Applied Materials & Interfaces

Amyloid‐Like Rapid Surface Modification for Antifouling and In‐Depth Remineralization of Dentine Tubules to Treat Dental Hypersensitivity

(2019) Chen Li et al.   ADVANCED MATERIALS

Triple-functional polyetheretherketone surface with enhanced bacteriostasis and anti-inflammatory and osseointegrative properties for implant application

(2019) Xiao Xu et al.   BIOMATERIALS

Fabrication of magnesium/zinc-metal organic framework on titanium implants to inhibit bacterial infection and promote bone regeneration

(2019) Xinkun Shen et al.   BIOMATERIALS

Biocompatible MoS2/PDA-RGD coating on titanium implant with antibacterial property via intrinsic ROS-independent oxidative stress and NIR irradiation

(2019) Zhang Yuan et al.   BIOMATERIALS

Impact of Antifouling PEG Layer on the Performance of Functional Peptides in Regulating Cell Behaviors

(2019) Qi Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultra-dense polymer brush coating reduces Staphylococcus epidermidis biofilms on medical implants and improves antibiotic treatment outcome

(2018) Sandra M. Skovdal et al.   Acta Biomaterialia

A Novel Hydrogel Surface Grafted With Dual Functional Peptides for Sustaining Long-Term Self-Renewal of Human Induced Pluripotent Stem Cells and Manipulating Their Osteoblastic Maturation

(2018) Yi Deng et al.   ADVANCED FUNCTIONAL MATERIALS

A Coating that Combines Lotus-Effect and Contact-Active Antimicrobial Properties on Silicone

(2018) Nicolas Rauner et al.   ADVANCED FUNCTIONAL MATERIALS

PLGA/β-TCP composite scaffold incorporating salvianolic acid B promotes bone fusion by angiogenesis and osteogenesis in a rat spinal fusion model

(2018) Sien Lin et al.   BIOMATERIALS

Anhydrous polymer-based coating with sustainable controlled release functionality for facile, efficacious impregnation, and delivery of antimicrobial peptides

(2018) Kaiyang Lim et al.   BIOTECHNOLOGY AND BIOENGINEERING

Conducting photopolymers on orthopeadic implants having a switch of priority between promoting osteogenic and antibacterial activity

(2018) Jingwen Liao et al.   Materials Horizons

Versatile Antibacterial Materials: An Emerging Arsenal for Combatting Bacterial Pathogens

(2018) Xiaokang Ding et al.   ADVANCED FUNCTIONAL MATERIALS

Temperature-Controlled Reversible Exposure and Hiding of Antimicrobial Peptides on an Implant for Killing Bacteria at Room Temperature and Improving Biocompatibility in Vivo

(2018) Jiezhao Zhan et al.   ACS Applied Materials & Interfaces

Antimicrobial coatings prepared from Dhvar-5-click-grafted chitosan powders

(2018) Mariana Barbosa et al.   Acta Biomaterialia

Functionalized Holmium-Doped Hollow Silica Nanospheres for Combined Sonodynamic and Hypoxia-Activated Therapy

(2018) Yanke Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Improvement in antibacterial properties and cytocompatibility of titanium by fluorine and oxygen dual plasma-based surface modification

(2018) Mian Chen et al.   APPLIED SURFACE SCIENCE

Antimicrobial Titanium Surface via Click-Immobilization of Peptide and Its in Vitro/Vivo Activity

(2018) Junjian Chen et al.   ACS Biomaterials-Science & Engineering

Antibacterial hyaluronic acid/chitosan multilayers onto smooth and micropatterned titanium surfaces

(2018) Ainara Valverde et al.   CARBOHYDRATE POLYMERS

The effect of quercetin delivery system on osteogenesis and angiogenesis under osteoporotic conditions

(2017) Yuning Zhou et al.   Journal of Materials Chemistry B

Microgroove and Collagen-poly(ε-caprolactone) Nanofiber Mesh Coating Improves the Mechanical Stability and Osseointegration of Titanium Implants

(2017) Morshed Khandaker et al.   Nanomaterials

Multifunctional Coating Improves Cell Adhesion on Titanium by using Cooperatively Acting Peptides

(2016) Mareen Pagel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

‘Lollipop’-shaped helical structure of a hybrid antimicrobial peptide of temporin B-lipopolysaccharide binding motif and mapping cationic residues in antibacterial activity

(2016) Harini Mohanram et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Biodegradable Mg-Cu alloy implants with antibacterial activity for the treatment of osteomyelitis: In vitro and in vivo evaluations

(2016) Yang Li et al.   BIOMATERIALS

All-trans retinoic acid preconditioning enhances proliferation, angiogenesis and migration of mesenchymal stem cellin vitroand enhances wound repairin vivo

(2016) M. Pourjafar et al.   CELL PROLIFERATION

Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology

(2016) Adi Ben Shoham et al.   DEVELOPMENT

Closed-Incision Negative-Pressure Therapy Versus Antimicrobial Dressings After Revision Hip and Knee Surgery: A Comparative Study

(2016) H. John Cooper et al.   JOURNAL OF ARTHROPLASTY

Tryptic Stability of Synthetic Bactenecin Derivatives Is Determined by the Side Chain Length of Cationic Residues and the Peptide Conformation

(2016) Mojtaba Bagheri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial Agents Used in the Treatment of Peri-Implantitis Alter the Physicochemistry and Cytocompatibility of Titanium Surfaces

(2016) Georgios A. Kotsakis et al.   JOURNAL OF PERIODONTOLOGY

Perigraft vascularization and incorporation of implanted Dacron prostheses are affected by rifampicin coating

(2016) Mohammed R. Moussavian et al.   JOURNAL OF VASCULAR SURGERY

Antibacterial titanium surfaces for medical implants

(2016) S. Ferraris et al.   Materials Science & Engineering C-Materials for Biological Applications

Layer-by-Layer-Assembled Healable Antifouling Films

(2015) Dongdong Chen et al.   ADVANCED MATERIALS

Toward a Molecular Understanding of the Antibacterial Mechanism of Copper-Bearing Titanium Alloys againstStaphylococcus aureus

(2015) Mei Li et al.   Advanced Healthcare Materials

Multi-biofunctionalization of a titanium surface with a mixture of peptides to achieve excellent antimicrobial activity and biocompatibility

(2015) Wang Lin et al.   Journal of Materials Chemistry B

Biofunctionalized titanium with anti-fouling resistance by grafting thermo-responsive polymer brushes for the prevention of peri-implantitis

(2015) Sang Jin Lee et al.   Journal of Materials Chemistry B

Novel Peptide-Based Platform for the Dual Presentation of Biologically Active Peptide Motifs on Biomaterials

(2014) Carlos Mas-Moruno et al.   ACS Applied Materials & Interfaces

Capillary Network-Like Organization of Endothelial Cells in PEGDA Scaffolds Encoded with Angiogenic Signals via Triple Helical Hybridization

(2014) Patrick J. Stahl et al.   ADVANCED FUNCTIONAL MATERIALS

A Hybrid Cationic Peptide Composed of Human β-Defensin-1 and Humanized θ-Defensin Sequences Exhibits Salt-Resistant Antimicrobial Activity

(2014) Sudar Olli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections

(2013) Mehdi Kazemzadeh-Narbat et al.   BIOMATERIALS

The promotion of antimicrobial activity on silicon substrates using a “click” immobilized short peptide

(2013) Lin Wang et al.   CHEMICAL COMMUNICATIONS

Synthesis of monodisperse Cu nanoparticles in Ionic Liquids: A synthetic and catalytic approach of in situ nanoparticles

(2013) Balaji Mohan et al.   SOLID STATE SCIENCES

Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis

(2012) Federica Finetti et al.   BIOCHEMICAL PHARMACOLOGY

Does Dual Antibiotic Prophylaxis Better Prevent Surgical Site Infections in Total Joint Arthroplasty?

(2012) Amy Sewick et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The biomimetic apatite-cefalotin coatings on modified titanium

(2012) Min-Kyung KANG et al.   DENTAL MATERIALS JOURNAL

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

The promotion of microvasculature formation in poly(ethylene glycol) diacrylate hydrogels by an immobilized VEGF-mimetic peptide

(2011) Julia E. Leslie-Barbick et al.   BIOMATERIALS

“Click” Immobilization on Alkylated Silicon Substrates: Model for the Study of Surface Bound Antimicrobial Peptides

(2011) Yan Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tandem “Click” Reactions at Acetylene-Terminated Si(100) Monolayers

(2011) Simone Ciampi et al.   LANGMUIR

Antibacterial iodine-supported titanium implants

(2010) T. Shirai et al.   Acta Biomaterialia

Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections

(2010) Mehdi Kazemzadeh-Narbat et al.   BIOMATERIALS

Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(i) acetylides

(2010) Jason E. Hein et al.   CHEMICAL SOCIETY REVIEWS

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Different Functionalization of the Internal and External Surfaces in Mesoporous Materials for Biosensing Applications Using “Click” Chemistry

(2010) Bin Guan et al.   LANGMUIR

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF

(2009) Ernestina Schipani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Use of Artificial Intelligence in the Design of Small Peptide Antibiotics Effective against a Broad Spectrum of Highly Antibiotic-Resistant Superbugs

(2008) Artem Cherkasov et al.   ACS Chemical Biology

Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide–alkyne “click” chemistry☆

(2008) J LUTZ et al.   ADVANCED DRUG DELIVERY REVIEWS

Increased bone contact to a calcium-incorporated oxidized commercially pure titanium implant: an in-vivo study in rabbits

(2008) V. Fröjd et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Bone Formation During Distraction Osteogenesis Is Dependent on Both VEGFR1 and VEGFR2 Signaling

(2008) Kimberly A Jacobsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH