Adult neurogenesis and antidepressant treatment; the surprise finding by Ron Duman and the field 20 years later

Identifying Immunophenotypes of Inflammation in Depression: Dismantling the Monolith

(2020) Jennifer C. Felger et al.   BIOLOGICAL PSYCHIATRY

The Bidirectional Relationship of Depression and Inflammation: Double Trouble

(2020) Eléonore Beurel et al.   NEURON

The role of allopregnanolone in depressive-like behaviors: Focus on neurotrophic proteins

(2020) Felipe Borges Almeida et al.   Neurobiology of Stress

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus

(2019) Victor M. Luna et al.   SCIENCE

Neurotrophic mechanisms underlying the rapid and sustained antidepressant actions of ketamine

(2019) Satoshi Deyama et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

(2018) Christoph Anacker et al.   NATURE

Neurotherapeutic Capacity of P7C3 Agents for the Treatment of Traumatic Brain Injury

(2018) Meghan O. Blaya et al.   NEUROPHARMACOLOGY

Neuroprotective efficacy of P7C3 compounds in primate hippocampus

(2018) Melissa D. Bauman et al.   Translational Psychiatry

Activation of GPR55 induces neuroprotection of hippocampal neurogenesis and immune responses of neural stem cells following chronic, systemic inflammation

(2018) Jeremy D. Hill et al.   BRAIN BEHAVIOR AND IMMUNITY

Adult Hippocampal Neurogenesis: A Coming-of-Age Story

(2018) H. Georg Kuhn et al.   JOURNAL OF NEUROSCIENCE

The neuroprotective compound P7C3-A20 promotes neurogenesis and improves cognitive function after ischemic stroke

(2017) Zachary B. Loris et al.   EXPERIMENTAL NEUROLOGY

The neurogenic compound, NSI-189 phosphate: a novel multi-domain treatment capable of pro-cognitive and antidepressant effects

(2017) Roger S. McIntyre et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response

(2017) Zhenzhong Ma et al.   Nature Communications

Adult hippocampal neuroplasticity triggers susceptibility to recurrent depression

(2017) N D Alves et al.   Translational Psychiatry

Integrating neuroimmune systems in the neurobiology of depression

(2016) Eric S. Wohleb et al.   NATURE REVIEWS NEUROSCIENCE

Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits

(2016) Kathleen M. McAvoy et al.   NEURON

Treatment of cognitive dysfunction in major depressive disorder—a review of the preclinical evidence for efficacy of selective serotonin reuptake inhibitors, serotonin–norepinephrine reuptake inhibitors and the multimodal-acting antidepressant vortioxetine

(2015) Alan L. Pehrson et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

(2015) M Fava et al.   MOLECULAR PSYCHIATRY

Mechanisms of stress in the brain

(2015) Bruce S McEwen et al.   NATURE NEUROSCIENCE

Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors

(2015) Alexis S Hill et al.   NEUROPSYCHOPHARMACOLOGY

The role of inflammatory cytokines as key modulators of neurogenesis

(2015) Alessandra Borsini et al.   TRENDS IN NEUROSCIENCES

Functional dissociation of adult-born neurons along the dorsoventral axis of the dentate gyrus

(2014) Melody V. Wu et al.   HIPPOCAMPUS

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

(2014) A K Walker et al.   MOLECULAR PSYCHIATRY

Activation of Mammalian Target of Rapamycin and Synaptogenesis: Role in the Actions of Rapid-Acting Antidepressants

(2013) Jason M. Dwyer et al.   BIOLOGICAL PSYCHIATRY

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice

(2013) Jean-Philippe Guilloux et al.   NEUROPHARMACOLOGY

Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders

(2012) Mazen A Kheirbek et al.   NATURE NEUROSCIENCE

A novel flow cytometry-based technique to measure adult neurogenesis in the brain

(2011) Robert Spoelgen et al.   JOURNAL OF NEUROCHEMISTRY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

A Synthetic 7,8-Dihydroxyflavone Derivative Promotes Neurogenesis and Exhibits Potent Antidepressant Effect

(2010) Xia Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Antidepressants increase neural progenitor cells in the human hippocampus

(2009) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise

(2008) Catharine H. Duman et al.   BEHAVIOURAL BRAIN RESEARCH

Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   BIOLOGICAL PSYCHIATRY

Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse

(2008) Darrick T. Balu et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS