4.7 Review

Consensus Guidelines for the Use of Fluorescence Imaging in Hepatobiliary Surgery

Journal

ANNALS OF SURGERY
Volume 274, Issue 1, Pages 97-106

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/SLA.0000000000004718

Keywords

anatomic liver resection; anatomical liver resection; cholecystectomy; colorectal liver metastasis (CRLM); fluorescence; fluorescence imaging; hepatocellular carcinoma (HCC); indocyanine green; intraoperative cholangiography; laparoscopic cholecystectomy; laparoscopic hepatectomy; laparoscopic liver resection; liver; liver resection; liver transplant; near infrared (NIR)

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Funding

  1. Stryker

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The Shanghai consensus recommendations provide practical guidance for the use of ICG in hepatobiliary surgery, presenting 7 key recommendations for clinical applications. By consolidating evidence and clinical experiences, experts derived consensus statements to enhance safety and technical feasibility in ICG fluorescence-guided hepatobiliary surgery, including laparoscopic cholecystectomy, liver segmentectomy, and liver transplantation.
Objective: To establish consensus recommendations for the use of fluorescence imaging with indocyanine green (ICG) in hepatobiliary surgery. Background: ICG fluorescence imaging has gained popularity in hepatobiliary surgery in recent years. However, there is varied evidence on the use, dosage, and timing of administration of ICG in clinical practice. To standardize the use of this imaging modality in hepatobiliary surgery, a panel of pioneering experts from the Asia-Pacific region sought to establish a set of consensus recommendations by consolidating the available evidence and clinical experiences. Methods: A total of 13 surgeons experienced in hepatobiliary surgery and/or minimally invasive surgery formed an expert consensus panel in Shanghai, China in October 2018. By the modified Delphi method, they presented the relevant evidence, discussed clinical experiences, and derived consensus statements on the use of ICG in hepatobiliary surgery. Each statement was discussed and modified until a unanimous consensus was achieved. Results: A total of 7 recommendations for the clinical applications of ICG in hepatobiliary surgery were formulated. Conclusions: The Shanghai consensus recommendations offer practical tips and techniques to augment the safety and technical feasibility of ICG fluorescence-guided hepatobiliary surgery, including laparoscopic cholecystectomy, liver segmentectomy, and liver transplantation.

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