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Title
RNA‐PROTACs: Degraders of RNA‐Binding Proteins
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-10-28
DOI
10.1002/anie.202012330
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- (2020) George M. Burslem et al. CELL
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- ARV-110: An oral androgen receptor PROTAC degrader for prostate cancer.
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- Proteolysis targeting chimeras (PROTACs) in ‘beyond rule-of-five’ chemical space: Recent progress and future challenges
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- Specific inhibition of splicing factor activity by decoy RNA oligonucleotides
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- The Effects of 2′-O-Methoxyethyl Oligonucleotides on Renal Function in Humans
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- Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation
- (2018) Colton M. Miller et al. Nucleic Acid Therapeutics
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- (2018) R.L. Juliano Nucleic Acid Therapeutics
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- (2018) Longfei Wang et al. Cell Reports
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- Structural basis of PROTAC cooperative recognition for selective protein degradation
- (2017) Morgan S Gadd et al. Nature Chemical Biology
- Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation
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- (2016) Pritha Ghosh et al. Molecular BioSystems
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- (2016) Colton M. Miller et al. NUCLEIC ACIDS RESEARCH
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- (2016) Benedikt M. Beckmann et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
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