Article
Chemistry, Analytical
Xin Liu, Dawei Fan, Chenchen Zhang, Xinrong Shao, Hongmin Ma, Yong Zhang, Xueying Wang, Qin Wei, Huangxian Ju
Summary: A novel ultrasensitive photoelectrochemical (PEC) antifouling immunosensor was developed using BiOBr/FeTPPCl/BiOI as matrix and PAA/PEG as hybrid antifouling interface, achieving quantitative determination of MDA-MB-231 cells through specific immunosensing interface and simple immunosensing method.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Jing-Jing Wei, Heng-Bo Li, Gui-Qing Wang, Jia-Ying Zheng, Ai-Jun Wang, Li-Ping Mei, Tiejun Zhao, Jiu-Ju Feng
Summary: Hepatocellular carcinoma is a life-threatening malignant tumor with high morbidity and mortality worldwide. A novel photoelectrochemical cytosensor was developed using hollow CdIn2S4/In2S3 microspheres, enabling the ultrasensitive and accurate detection of HepG2 cells. This work paves the way for sensitive detection of various tumor cells, holding great potential for early clinical diagnosis and treatment.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Guo-Na Huo, Sha-Sha Zhang, Yue-Liu Li, Jia-Xing Li, Zhao Yue, Wei-Ping Huang, Shou-Min Zhang, Bao-Lin Zhu
Summary: Heterojunction structures formed by TiO2 nanotubes can enhance the photoelectric properties by preventing the recombination of electron-hole pairs. A CdS-TiO2NTs photoelectrochemical sensor was fabricated using the hydrothermal-impregnation method, showing good PEC performance under visible light.
Article
Chemistry, Physical
Pannan Kyesmen, Nolwazi Nombona, Mmantsae Diale
Summary: This research focused on preparing nanostructured heterojunction of alpha-Fe2O3 and porous CuO composites as photoanodes for PEC water splitting. The formations of heterojunction and porous surface morphology facilitated charge separation and enhanced PEC efficiency. The reduced bandgap and increased photon absorption in the visible spectrum were key factors in improving photocurrent density.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Materials Science, Multidisciplinary
Rongrong Ma, Rajesh Pathak, Dongping Zheng, Yingjie Zhang, Jie Xing, Junhong Liu, Yuanyuan Jiang, Mingxing Xiao, Fan Wu
Summary: The three-dimensional ZnO/CuO nano-heterogeneous hierarchical structure array demonstrated significant absorption of visible light and enhanced photocurrent. The charge dynamics processes were studied by comparing electrochemical impedance spectroscopy and intensity modulation photocurrent spectroscopy in both the core-shell ZnO/CuO nano-heterostructure array and the three-dimensional ZnO/CuO nano-heterostructure array.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2021)
Article
Chemistry, Analytical
Zhichao Yu, Hexiang Gong, Yuxuan Li, Jianhui Xu, Jin Zhang, Yongyi Zeng, Xiaolong Liu, Dianping Tang
Summary: An innovative portable self-powered photoelectrochemical sensing platform was developed for rapid and sensitive detection of specific protein biomarkers, with high sensitivity and low detection limit achieved by integrating various functional materials and a photochromic visualization platform. The combination of chemiluminescence and photoelectric signal output successfully enabled the sensitive detection of abnormal protein through a novel approach.
ANALYTICAL CHEMISTRY
(2021)
Article
Biophysics
Gang Wang, Yachao Zhang, Shi Tang, Shuning Chen, Fangbo Zou, Hongxiu Yuan, Jin Jiao
Summary: The key factor for glioma invasion and metastasis is the circulating tumor cells (CTCs) undergoing epithelial-mesenchymal transition (EMT). This study developed a multivalent aptamer nanoscaffold-based electrochemical cytosensor (MAS-cytosensor) to efficiently detect EMT-CTCs. The MAS-cytosensor can detect EMT-CTCs sensitively and allows for further downstream analysis after release with high viability.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Jiarong Luo, Qin Zeng, Shuping Liu, Qingya Wei, Zaoxia Wang, Minghui Yang, Yingping Zou, Limin Lu
Summary: In this study, a sensitive photoelectrochemical (PEC) biosensor was developed for the detection of circulating tumor cells (CTCs) using organic PM6:Y6 p-n heterojunction as the photoactive matrix. The detection of CTCs was achieved through the sandwich protocol, with magnetic nanobeads (MNs) used for capturing and separating the CTCs. The photocurrent response of the PEC sensor was enhanced using the localized surface plasmon resonance (LSPR) of gold nanoparticles (Au NPs) and silver nanoparticles (Ag NPs) generated by a silver staining reaction.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biochemical Research Methods
Fereshteh Vajhadin, Mohammad Mazloum-Ardakani, Bikash R. Sahoo, Seyed Mohammad Moshtaghioun, Martin C. Hartel
Summary: The fabrication of an electrochemical cytosensing platform for cancer monitoring by isolating cancer cells using magnetic nanoparticles functionalized with folic acid and chitosan was demonstrated. The platform utilizes a three-dimensional hierarchical structure of polyaniline-folic acid nanohybrids, which exhibit high affinity for folate bioreceptors on cancer cells and good conductivity. The limit of detection is 4 cells mL-1 with a linear range from 50 to 106 cells mL-1.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
Yufei Cheng, Ming Gong, Tete Xu, Enzhou Liu, Jun Fan, Hui Miao, Xiaoyun Hu
Summary: In this study, a core-shell heterostructure nanorod was successfully fabricated, allowing for efficient photocurrent generation and enhanced stability and H2 production rate under neutral conditions. This provides new insights into the design of antimony chalcogenide heterostructure photoelectrodes.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Alireza Sanati, Yasaman Esmaeili, Mohammad Khavani, Elham Bidram, Azadeh Rahimi, Arezou Dabiri, Mohammad Rafienia, Nafise Arbab Jolfaie, Mohammad R. K. Mofrad, Shaghayegh Haghjooy Javanmard, Laleh Shariati, Ali Zarrabi
Summary: Developing smartphone technology for point-of-care diagnosis is a favorable trend in biosensors, providing better accessibility and convenience. The detection of circulating tumor cells (CTCs) is a recent method for early cancer diagnosis. This study introduces a new smartphone-assisted lab-in-a-tube device for detecting Mucin 1 (MUC1) overexpressed tumor-derived cell lines using gold nanoclusters (GNCs)-based aptasensor.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Physical
Yuhei Taga, Zhenhua Pan, Kenji Katayama, Woon Yong Sohn
Summary: Developing an efficient photoanode is crucial for sustainable hydrogen energy production. By constructing a solid-state junction and applying an inverse opal structure, a BiVO4/WO3-IO photoanode was developed and demonstrated better performance in photoelectrochemical water splitting compared to a bare WO3 photoanode. This successful combination provides a promising approach for utilizing solar energy in visible-light-responsive photoanodes.
ACS APPLIED ENERGY MATERIALS
(2022)
Review
Electrochemistry
Xiao-Rui Li, Yi-Ge Zhou
Summary: Circulating tumor cell (CTC) serves as a crucial biomarker for early cancer diagnosis, and electrochemical CTC sensors have shown advantages in simplicity, speed, cost-effectiveness, and miniaturization. Recent developments in electrochemical cytosensors over the past 5 years have focused on different detection principles with a particular emphasis on the challenges and importance of single CTC detection. Future prospects lie in impact methods for single CTC analysis.
ELECTROCHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Hongxia Qian, Zhifeng Liu, Zhengang Guo, Mengnan Ruan, Weiguo Yan
Summary: This study investigated the photoelectrochemical performance of ternary sulfide photoelectrodes with the same nanostructure and applied bidirectional p-n heterojunctions. The use of ZnIn2S4/CuInS2 and CuInS2/ZnIn2S4 as photoanode and photocathode in the unassisted tandem PEC cell device achieved a relatively high photocurrent density of 0.06 mA cm(-2), providing new ideas for the design and manufacture of high-efficiency unassisted tandem PEC cell devices.
CHEMICAL COMMUNICATIONS
(2021)
Article
Biophysics
Huawei Shen, Liyu Liu, Zuowei Yuan, Qian Liu, Baiying Li, Ming Zhang, Hejun Tang, Juan Zhang, Shiqiao Zhao
Summary: A highly specific and sensitive cytosensor was developed using a dual-recognition strategy and metallic-organic nanoclusters, enabling accurate detection of circulating tumor cells even in whole blood.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Physical
Zirui Wang, Haoxuan He, Junjian Zhao, Xiaoxia Jian, Changyong Liu, Zhida Gao Supervison, Yan-Yan Song
Summary: Researchers have developed an antibacterial film that addresses the low photocatalytic efficiency of titania (TiO2) and can combat hospital-acquired infections and antibiotic-resistant pathogens, which are significant threats to human health.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Junli Guo, Xuao Liu, Junjian Zhao, Huijie Xu, Zhida Gao, Zeng-Qiang Wu, Yan-Yan Song
Summary: Inspired by natural ionic channels, researchers developed an asymmetrical MOF-in-nanochannel architecture to discriminate monosaccharide enantiomers. The architecture combines oxidase-mimicking and Fenton-like catalysis in homochiral mesoporous CuMOF pockets, and the identification performance is enhanced by the increased oxidase-mimicking activity of Au nanoparticles under LSPR excitation. This study provides a promising strategy for designing an enantiomer discrimination device and offers insights into the origin of stereoselectivity in natural enzymes.
Article
Chemistry, Analytical
Zhechen Zhang, Haoxuan He, Junli Guo, Chenxi Zhao, Zhida Gao, Yan-Yan Song
Summary: Chiral recognition is a critical issue in the biomedical and pharmaceutical research fields. A power-free sensing platform based on bovine serum albumin (BSA) was proposed for sensitive chiral recognition of enantiomers. By measuring the output voltage, the enantioselectivity difference between L-Arg and D-Arg on a BSA-modified carbon substrate can be directly determined. The use of surface charges via the cyclization reaction between NO and O-phenylenediamine significantly enhances the sensitivity and specificity of enantioselective identification, with a limit of detection (LOD) as low as 76.0 nM. The flexible chips can function under deformation without sacrificing output performance, providing a new approach for the detection of chiral molecules and potential applications in wearable technology.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Huijie Xu, Junli Guo, Junjian Zhao, Zhida Gao, Yan-Yan Song
Summary: In this study, an enantioselective artificial architecture was constructed on TiO2 nanochannels, using homochiral Ti-based metal-organic frameworks (MOFs) as the skeleton, Fe(III) as peroxidase-mimicking centers, and L-tartaric acid (TA) as a chiral recognition selector. The selective recognition of cystine enantiomers was achieved through hydrogen bonds formed between chiral cystine and the host, and the change in peroxidase-like activity of the nanochannels was monitored through ionic current signatures.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Zhen-Kun He, Yongxin Lu, Jiahui Zhao, Junjian Zhao, Zhida Gao, Yan-Yan Song
Summary: Solar-driven photo-electrocatalysis using semiconductor photoelectrodes shows promise for sustainable and environmentally friendly energy utilization. However, the limitations of TiO2-based materials, including limited light absorption and low carrier density, hinder their practical applications. By engineering nanoarchitectured photocatalysts, their optical properties can be tailored to increase light-harvesting efficiencies.
APPLIED SURFACE SCIENCE
(2023)
Article
Engineering, Environmental
Jing Xu, Xiaoxia Jian, Junli Guo, Junjian Zhao, Jie Tang, Yue Zhao, Jingwen Xu, Zhida Gao, Yan-Yan Song
Summary: Enantiomeric identification is crucial in various fields, and this study developed an enantioselective surface-enhanced Raman scattering (SERS) substrate for chiral molecule detection and quantification. The substrate integrated homochiral MIL-101(Fe) with oxidase (GOx)-mimicking Au nanoparticles (Au/Chiral-MIL-101(Fe)), which exhibited selective recognition abilities for Glu enantiomers. The hybrid nanoreactors demonstrated high catalytic performance and sensitivity, enabling the quantification of Glu enantiomers with a low limit of detection.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Chenxi Zhao, Yanjian Li, Junjian Zhao, Hailong Li, Jingwen Xu, Zhida Gao, Chen Ding, Yan-Yan Song
Summary: This article introduces a double-layered test-to-treat pad for visual monitoring and selective treatment of drug-sensitive/drug-resistant bacterial infections. The pad consists of an inner layer for infection detection and inactivation of drug-sensitive bacteria, and an outer layer for antibacterial therapy. By utilizing this design, bacterial infections can be effectively controlled without antibiotic abuse, promoting wound healing.
Article
Chemistry, Analytical
Huijie Xu, Junli Guo, Junjian Zhao, Zhida Gao, Yan-Yan Song
Summary: In this study, an electrochemical platform based on TiO2 nanochannels was developed for the specific recognition of reducing enantiomers. Through a recognition-reaction zone design, combined with the chiral recognition environment and the enzyme-like activity of nanosheets, quantitative identification of L- and D-Pen was achieved.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tiantian Su, Junli Guo, Zhen-Kun He, Junjian Zhao, Zhida Gao, Yan-Yan Song
Summary: Enzyme-mimicking nanoparticles are crucial in catalytic processes, and understanding and tuning their performance is important for biological applications. Researchers developed an efficient electrochemical method for monitoring the glucose oxidase-like activity of single nanoparticle through collision events. They used brush-like sulfonate-doped polyaniline decorated on TiO2 nanotube arrays as the electrode and evaluated the oxidase-like activity of individual Au nanoparticles through collision-induced proton generation. By investigating the perturbation of the electrical double layer of the nanoparticles, the relationship between the measured oxidase-like activities and the localized surface plasmon resonance and temperature was revealed.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tianmeng Wang, Zirui Wang, Jiani Hao, Junjian Zhao, Junli Guo, Zhida Gao, Yan-Yan Song
Summary: In this study, a target-driven electron donor generation method was developed to detect glutathione (GSH) in a photoelectrochemical (PEC) electrode. The use of mesoporous MIL-125-(Ti) and Pt nanoclusters (NCs) improved the charge transfer and oxidation reaction, leading to high-sensitivity detection of GSH. This approach may offer a new route for developing sensitive and selective PEC biosensors in complex biological environments.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Yiming Wang, Min Li, Zirui Wang, Jing Xu, Junjian Zhao, Zhi-Da Gao, Yan-Yan Song
Summary: Pesticides pose a serious risk to public health, and the sensitive, rapid, visual, and on-site detection of pesticides in a real sample remains a challenge. This study presents a visual and rapid sensing device based on the photothermal effect, which can detect organophosphorus pesticides with excellent sensitivity, ease of application, and specificity. The device has the potential for real-time detection of pesticide residues in agricultural products.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Rongyang Kou, Haoxuan He, Yongxin Lu, Haiquan Wang, Jingwen Xu, Yan-Yan Song, Zhida Gao
Summary: A sensitive H2S sensing chip was developed based on Pt nanocluster decorated TiO2@ZnFe2O4 nanotube arrays for room temperature operation. The chip showed high sensing response and excellent specificity, benefiting from the plentiful defects induced by Pt nanocluster and the selectivity of ZnFe2O4 towards H2S. The sensing reactions of H2S were mainly triggered by the abundant energetic active defects in the absence of traditional thermal energy and UV irradiation. The resulting samples exhibited a remarkably high sensitivity for H2S with a low limit of detection and good selectivity, reproducibility, and long-term storage stability.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Zhen-Kun He, Jiahui Zhao, Keke Li, Junjian Zhao, Haoxuan He, Zhida Gao, Yan-Yan Song
Summary: The authors developed a formaldehyde sensor using a spaced TiO2 nanotube array as a scaffold and electron collector. The sensor showed high sensitivity, stability, reproducibility, and fast response and recovery times, making it suitable for medical diagnosis, environmental monitoring, and other intelligent sensing systems.
Article
Chemistry, Multidisciplinary
Xifeng Zhang, Jiahui Zhao, Haiquan Wang, Haoxuan He, Zhen-kun He, Junjian Zhao, Zhida Gao, Yan-Yan Song
Summary: In this study, a gas sensing platform was developed for sensitively and specifically detecting trace H2S in a high-humidity atmosphere. The platform showed rapid response and recovery abilities, as well as remarkable detection sensitivity for H2S. It also exhibited good performance in dark conditions and in detecting trace H2S in human exhaled breath.
Article
Materials Science, Biomaterials
Junhan Li, Jingwen Xu, Yundian Liu, Jing Xu, Lingling Yang, Zhida Gao, Yan-Yan Song
Summary: By utilizing self-standing Au/TiO2 nanotubes as a surface-enhanced Raman spectroscopy (SERS) substrate, rapid and sensitive discrimination of bacterial contamination is achieved through the hydrophobic interaction between the volatile metabolites released from pathogenic bacteria and the SERS substrate. The SERS platform demonstrates good discrimination ability between benign and pathogenic bacteria within 4 minutes, allowing for the detection of Escherichia coli (E. coli) at low concentrations. This technique has the potential to serve as a guide for antibiotic treatment, offering reliable and rapid guidance for interrelated bacteria therapy.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)