AN UPDATE ON BROWN ADIPOSE TISSUE BIOLOGY: A DISCUSSION OF RECENT FINDINGS

γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis

(2020) Bo Hu et al.   NATURE

The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

(2020) Brian S. Finlin et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

(2020) Alana E. O’Mara et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity

(2020) Alfred K. Ramirez et al.   Nature Communications

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

(2020) Farnaz Shamsi et al.   Nature Communications

Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation

(2020) Denis P. Blondin et al.   Cell Metabolism

SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue

(2019) Lin Shuai et al.   DIABETES

Function and Mechanism of Long Noncoding RNAs in Adipocyte Biology

(2019) Lei Sun et al.   DIABETES

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

(2019) GuoXiao Wang et al.   MOLECULAR CELL

Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis

(2019) Xing Zeng et al.   NATURE

Bladder drug mirabegron exacerbates atherosclerosis through activation of brown fat-mediated lipolysis

(2019) Wenhai Sui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells

(2019) So Yun Min et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

(2019) Atul S. Deshmukh et al.   Cell Metabolism

Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue

(2019) Anying Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Adipose tissue NAD+ biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice

(2019) Shintaro Yamaguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake

(2018) Kristin I. Stanford et al.   Cell Metabolism

A 2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21

(2018) Cheng-Chao Ruan et al.   Cell Metabolism

Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist

(2018) Alison S. Baskin et al.   DIABETES

The Common and Distinct Features of Brown and Beige Adipocytes

(2018) Kenji Ikeda et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin

(2018) Xingxing Kong et al.   Cell Metabolism

Acute physical exercise increases leptin-induced hypothalamic extracellular signal-regulated kinase1/2 phosphorylation and thermogenesis of obese mice

(2018) Rafael Calais Gaspar et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nicotinamide riboside induces a thermogenic response in lean mice

(2018) Barbara M. Crisol et al.   LIFE SCIENCES

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

Mapping of human brown adipose tissue in lean and obese young men

(2017) Brooks P. Leitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Chronic Athletic Activity on Brown Fat in Young Women

(2016) Vibha Singhal et al.   PLoS One

Low brown adipose tissue activity in endurance-trained compared with lean sedentary men

(2015) M J Vosselman et al.   INTERNATIONAL JOURNAL OF OBESITY

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans

(2014) M. Chondronikola et al.   DIABETES

20 YEARS OF LEPTIN: Human disorders of leptin action

(2014) I Sadaf Farooqi et al.   JOURNAL OF ENDOCRINOLOGY

Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans

(2013) M Matsushita et al.   INTERNATIONAL JOURNAL OF OBESITY

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Diet-induced thermogenesis and substrate oxidation are not different between lean and obese women after two different isocaloric meals, one rich in protein and one rich in fat

(2008) Nicholas Tentolouris et al.   METABOLISM-CLINICAL AND EXPERIMENTAL