A Biomimetic, Copolymeric Membrane for Cell‐Stretch Experiments with Pulmonary Epithelial Cells at the Air‐Liquid Interface

Innovative preclinical models for pulmonary drug delivery research

(2020) Stephan Ehrmann et al.   Expert Opinion on Drug Delivery

Advancing human in vitro pulmonary disease models in preclinical research: opportunities for lung-on-chips

(2020) Arbel Artzy-Schnirman et al.   Expert Opinion on Drug Delivery

Development of a dynamic in vitro stretch model of the alveolar interface with aerosol delivery

(2020) Daniele Cei et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evolution of Bioengineered Lung Models: Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology

(2019) Ali Doryab et al.   ADVANCED FUNCTIONAL MATERIALS

Personalized medicine for patients with COPD: where are we?

(2019) Frits ME Franssen et al.   International Journal of Chronic Obstructive Pulmonary Disease

Mechanical strain mimicking breathing amplifies alterations in gene expression induced by SiO2 NPs in lung epithelial cells

(2019) Carmen Schmitz et al.   Nanotoxicology

Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices

(2019) Timothy S. Frost et al.   Micromachines

Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline

(2019) Arbel Artzy-Schnirman et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells

(2019) Huijuan Wu et al.   CELL

Suitability of a PLCL fibrous scaffold for soft tissue engineering applications: A combined biological and mechanical characterisation

(2018) Cédric P Laurent et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Medium throughput breathing human primary cell alveolus-on-chip model

(2018) Janick D. Stucki et al.   Scientific Reports

A comprehensive screening platform for aerosolizable protein formulations for intranasal and pulmonary drug delivery

(2017) Martina Röhm et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biokinetics of Aerosolized Liposomal Ciclosporin A in Human Lung Cells In Vitro Using an Air-Liquid Cell Interface Exposure System

(2017) Otmar Schmid et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice

(2017) Koustav Ganguly et al.   Particle and Fibre Toxicology

Electrospun Decellularized Lung Matrix Scaffold for Airway Smooth Muscle Culture

(2017) Bethany M. Young et al.   ACS Biomaterials-Science & Engineering

Electrospun Decellularized Lung Matrix Scaffold for Airway Smooth Muscle Culture

(2017) Bethany M. Young et al.   ACS Biomaterials Science & Engineering

Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma

(2017) N. Higuita-Castro et al.   Scientific Reports

Advances in pulmonary therapy and drug development: Lung tissue engineering to lung-on-a-chip

(2016) Ali Doryab et al.   BIOTECHNOLOGY ADVANCES

Bridging the Gap Between Science and Clinical Efficacy: Physiology, Imaging, and Modeling of Aerosols in the Lung

(2016) Chantal Darquenne et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Surface area is the biologically most effective dose metric for acute nanoparticle toxicity in the lung

(2016) Otmar Schmid et al.   JOURNAL OF AEROSOL SCIENCE

Superoxide mediates tight junction complex dissociation in cyclically stretched lung slices

(2016) Min Jae Song et al.   JOURNAL OF BIOMECHANICS

Evaluation of cell binding to collagen and gelatin: a study of the effect of 2D and 3D architecture and surface chemistry

(2016) Natalia Davidenko et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Applicability of avidin protein coated mesoporous silica nanoparticles as drug carriers in the lung

(2016) S. H. van Rijt et al.   Nanoscale

A lung-on-a-chip array with an integrated bio-inspired respiration mechanism

(2015) Andreas O. Stucki et al.   LAB ON A CHIP

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

(2015) Brendon M. Baker et al.   NATURE MATERIALS

A coculture model of the lung–blood barrier: The role of activated phagocytic cells

(2015) Katrien Luyts et al.   TOXICOLOGY IN VITRO

Simple surface engineering of polydimethylsiloxane with polydopamine for stabilized mesenchymal stem cell adhesion and multipotency

(2015) Yon Jin Chuah et al.   Scientific Reports

Efficient Bioactive Delivery of Aerosolized Drugs to Human Pulmonary Epithelial Cells Cultured in Air–Liquid Interface Conditions

(2014) Anke-Gabriele Lenz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Identification of multiple cellular uptake pathways of polystyrene nanoparticles and factors affecting the uptake: Relevance for drug delivery systems

(2014) Rebuma Firdessa et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Simultaneous adsorptive removal of methylene blue and copper ions from aqueous solution by ferrocene-modified cation exchange resin

(2014) Qian Wang et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Using Fourier transform IR spectroscopy to analyze biological materials

(2014) Matthew J Baker et al.   Nature Protocols

Rac1 pathway mediates stretch response in pulmonary alveolar epithelial cells

(2013) Brian C. DiPaolo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

(2013) Sebastian G Klein et al.   Particle and Fibre Toxicology

Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics

(2013) Akiko Mammoto et al.   Nature Communications

Quantum Dot Cytotoxicity and Ways To Reduce It

(2012) Françoise M. Winnik et al.   ACCOUNTS OF CHEMICAL RESEARCH

Differences in the Biokinetics of Inhaled Nano- versus Micrometer-Sized Particles

(2012) Wolfgang G. Kreyling et al.   ACCOUNTS OF CHEMICAL RESEARCH

Immobilization of Gelatin onto Poly(Glycidyl Methacrylate)-Grafted Polycaprolactone Substrates for Improved Cell–Material Interactions

(2012) Shaojun Yuan et al.   Biointerphases

Fabrication and characterization of PCL/gelatin composite nanofibrous scaffold for tissue engineering applications by electrospinning method

(2012) Sneh Gautam et al.   Materials Science & Engineering C-Materials for Biological Applications

In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung—A dialog between aerosol science and biology

(2011) Hanns-Rudolf Paur et al.   JOURNAL OF AEROSOL SCIENCE

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Extracellular Matrix Influences Alveolar Epithelial Claudin Expression and Barrier Function

(2009) Michael Koval et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Biological implications of polydimethylsiloxane-based microfluidic cell culture

(2009) Keil J. Regehr et al.   LAB ON A CHIP

A high-throughput screening method based on stably transformed human cells was used to determine the immunotoxic effects of fluoranthene and other PAHs

(2008) Gertie Janneke Oostingh et al.   TOXICOLOGY IN VITRO