A chondrogenesis induction system based on a functionalized hyaluronic acid hydrogel sequentially promoting hMSC proliferation, condensation, differentiation, and matrix deposition

Synergistic Effects of Kartogenin and Transforming Growth Factor‐β3 on Chondrogenesis of Human Umbilical Cord Mesenchymal Stem Cells In Vitro

(2020) Yanhong Zhao et al.   Orthopaedic Surgery

Injectable stem cell-laden supramolecular hydrogels enhance in situ osteochondral regeneration via the sustained co-delivery of hydrophilic and hydrophobic chondrogenic molecules

(2019) Jianbin Xu et al.   BIOMATERIALS

In situ gas foaming based on magnesium particle degradation: A novel approach to fabricate injectable macroporous hydrogels

(2019) Yanmei Tang et al.   BIOMATERIALS

Icariin conjugated hyaluronic acid/collagen hydrogel for osteochondral interface restoration

(2018) Jirong Yang et al.   Acta Biomaterialia

Single-cell RNA-seq analysis reveals the progression of human osteoarthritis

(2018) Quanbo Ji et al.   ANNALS OF THE RHEUMATIC DISEASES

Time-responsive osteogenic niche of stem cells: A sequentially triggered, dual-peptide loaded, alginate hybrid system for promoting cell activity and osteo-differentiation

(2018) Zuyuan Luo et al.   BIOMATERIALS

Hyaluronate-alginate hybrid hydrogels modified with biomimetic peptides for controlling the chondrocyte phenotype

(2018) Hyoseok An et al.   CARBOHYDRATE POLYMERS

Chitosan-based hydrogels: Preparation, properties and applications

(2018) Zahra Shariatinia et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Hyaluronic acid, an efficient biomacromolecule for treatment of inflammatory skin and joint diseases: A review of recent developments and critical appraisal of preclinical and clinical investigations

(2018) Li Hui Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A MMP7-sensitive photoclickable biomimetic hydrogel for MSC encapsulation towards engineering human cartilage

(2018) Elizabeth A. Aisenbrey et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Dose and Timing of N-Cadherin Mimetic Peptides Regulate MSC Chondrogenesis within Hydrogels

(2018) Mi Y. Kwon et al.   Advanced Healthcare Materials

A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects

(2018) A. Petersen et al.   Nature Communications

Tissue Engineering for the Temporomandibular Joint

(2018) Timothy M. Acri et al.   Advanced Healthcare Materials

Silk fibroin/cartilage extracellular matrix scaffolds with sequential delivery of TGF-β3 for chondrogenic differentiation of adipose-derived stem cells

(2017) Qiang Yang et al.   International Journal of Nanomedicine

Mechanical confinement regulates cartilage matrix formation by chondrocytes

(2017) Hong-pyo Lee et al.   NATURE MATERIALS

Development of kartogenin-conjugated chitosan–hyaluronic acid hydrogel for nucleus pulposus regeneration

(2017) Yanxia Zhu et al.   Biomaterials Science

Kartogenin-Incorporated Thermogel Supports Stem Cells for Significant Cartilage Regeneration

(2016) Xuezhou Li et al.   ACS Applied Materials & Interfaces

Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration

(2016) Dongquan Shi et al.   ACS Nano

Differentiation of mesenchymal stem cells for cartilage tissue engineering: Individual and synergetic effects of three-dimensional environment and mechanical loading

(2016) J.A. Panadero et al.   Acta Biomaterialia

Hydrogels functionalized with N-cadherin mimetic peptide enhance osteogenesis of hMSCs by emulating the osteogenic niche

(2016) Meiling Zhu et al.   BIOMATERIALS

Mesenchymal cells condensation-inducible mesh scaffolds for cartilage tissue engineering

(2016) In Gul Kim et al.   BIOMATERIALS

Tissue engineering strategies to study cartilage development, degeneration and regeneration

(2015) Maumita Bhattacharjee et al.   ADVANCED DRUG DELIVERY REVIEWS

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

A Bi-Lineage Conducive Scaffold for Osteochondral Defect Regeneration

(2014) Yan Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration

(2014) Mi Lan Kang et al.   BIOMATERIALS

Recapitulating endochondral ossification: a promising route toin vivobone regeneration

(2014) Emmet M. Thompson et al.   Journal of Tissue Engineering and Regenerative Medicine

Cell-Mediated Degradation Regulates Human Mesenchymal Stem Cell Chondrogenesis and Hypertrophy in MMP-Sensitive Hyaluronic Acid Hydrogels

(2014) Qian Feng et al.   PLoS One

Design of cell–matrix interactions in hyaluronic acid hydrogel scaffolds

(2013) Jonathan Lam et al.   Acta Biomaterialia

Injectable alginate hydrogels for cell delivery in tissue engineering

(2013) Sílvia J. Bidarra et al.   Acta Biomaterialia

The modulation of MSC integrin expression by RGD presentation

(2013) Jonathan Lam et al.   BIOMATERIALS

Fibrous hyaluronic acid hydrogels that direct MSC chondrogenesis through mechanical and adhesive cues

(2013) Iris L. Kim et al.   BIOMATERIALS

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis

(2013) L. Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of the Endochondral Skeleton

(2013) F. Long et al.   Cold Spring Harbor Perspectives in Biology

The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy

(2012) Liming Bian et al.   BIOMATERIALS

Unlike Bone, Cartilage Regeneration Remains Elusive

(2012) D. J. Huey et al.   SCIENCE

A Stem Cell-Based Approach to Cartilage Repair

(2012) K. Johnson et al.   SCIENCE

Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo

(2011) Liming Bian et al.   BIOMATERIALS

Hydrogel design for cartilage tissue engineering: A case study with hyaluronic acid

(2011) Iris L. Kim et al.   BIOMATERIALS

Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine

(2011) Glenn D. Prestwich   JOURNAL OF CONTROLLED RELEASE

The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels

(2010) Yuguo Lei et al.   BIOMATERIALS

TGF-β3 inhibits chondrogenesis by suppressing precartilage condensation through stimulation of N-cadherin shedding and reduction of cRREB-1 expression

(2010) Eun-Jung Jin et al.   MOLECULES AND CELLS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Multivalent Integrin-Specific Ligands Enhance Tissue Healing and Biomaterial Integration

(2010) T. A. Petrie et al.   Science Translational Medicine

Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering

(2010) Nasim Annabi et al.   TISSUE ENGINEERING PART B-REVIEWS

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY