Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial

The joint effect of aging and HIV infection on microstructure of white matter bundles

(2019) Taylor Kuhn et al.   HUMAN BRAIN MAPPING

Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans

(2018) Emily Tubbs et al.   DIABETES

High Prevalence of Sarcopenia in HIV-Infected Individuals

(2018) Patricia Echeverría et al.   Biomed Research International

Systemic Inflammation Characterizes Lack of Metabolic Health in Nonobese HIV-Infected Men

(2018) Ana N. Monczor et al.   MEDIATORS OF INFLAMMATION

Global and regional brain hypometabolism on FDG-PET in treated HIV-infected individuals

(2018) Dima A. Hammoud et al.   NEUROLOGY

Skeletal muscle insulin resistance: role of mitochondria and other ROS sources

(2017) Sergio Di Meo et al.   JOURNAL OF ENDOCRINOLOGY

HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging

(2017) Ying Wang et al.   NEUROPHARMACOLOGY

Diminished physical function in older HIV-infected adults in the Southeastern U.S. despite successful antiretroviral therapy

(2017) Audrey L. Khoury et al.   PLoS One

SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity

(2017) Jingxin Liu et al.   Cell Death & Disease

Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients

(2016) Kalpana J. Kallianpur et al.   MITOCHONDRION

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

Increasing glutathione concentrations with cysteine and glycine supplementation lowers inflammation in HIV patients

(2015) Rajagopal V. Sekhar et al.   AIDS

Accelerated Longitudinal Gait Speed Decline in HIV-Infected Older Men

(2015) Jennifer A. Schrack et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione

(2013) Dan Nguyen et al.   AGING CELL

Persistently Elevated Serum Interleukin-6 Predicts Mortality Among Adults Receiving Combination Antiretroviral Therapy in Botswana: Results from a Clinical Trial

(2013) Bethan McDonald et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on Mitochondrial Fuel Oxidation, Insulin Sensitivity, and Body Composition in Older HIV-Infected Patients

(2013) Dan Nguyen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Corneal Endothelial Cells Provide Evidence of Accelerated Cellular Senescence Associated with HIV Infection: A Case-Control Study

(2013) Sophia Pathai et al.   PLoS One

SIRT3 regulation of mitochondrial oxidative stress

(2012) Alexandra S. Bause et al.   EXPERIMENTAL GERONTOLOGY

Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population

(2011) G. Guaraldi et al.   CLINICAL INFECTIOUS DISEASES

Gait Speed and Survival in Older Adults

(2011) Stephanie Studenski   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Accelerated aging and human immunodeficiency virus infection: Emerging challenges of growing older in the era of successful antiretroviral therapy

(2011) Ramona Bhatia et al.   JOURNAL OF NEUROVIROLOGY

Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations

(2011) Brendan A I Payne et al.   NATURE GENETICS

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide

(2008) Shaji K. Chacko et al.   JOURNAL OF APPLIED PHYSIOLOGY

BDNF is essential to promote persistence of long-term memory storage

(2008) P. Bekinschtein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA