Age-Dependency of Neurite Outgrowth in Postnatal Mouse Cochlear Spiral Ganglion Explants

Myelin-induced inhibition in a spiral ganglion organ culture – Approaching a natural environment in vitro

(2017) Benedikt Kramer et al.   NEUROSCIENCE

Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination

(2015) Jana Schwieger et al.   PLoS One

Biochemical and Biophysical Investigation of the Brain-derived Neurotrophic Factor Mimetic 7,8-Dihydroxyflavone in the Binding and Activation of the TrkB Receptor

(2014) Xia Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Postnatal Expression of Neurotrophic Factors Accessible to Spiral Ganglion Neurons in the Auditory System of Adult Hearing and Deafened Rats

(2014) E. M. Bailey et al.   JOURNAL OF NEUROSCIENCE

A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease

(2014) Daniel Todd et al.   PLoS One

Changes in responsiveness of rat spiral ganglion neurons to neurotrophins across age: differential regulation of survival and neuritogenesis

(2013) Kenji Kondo et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Protection of Spiral Ganglion Neurons from Degeneration Using Small-Molecule TrkB Receptor Agonists

(2013) Q. Yu et al.   JOURNAL OF NEUROSCIENCE

Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

(2013) Frank M. Longo et al.   NATURE REVIEWS DRUG DISCOVERY

TGF-beta superfamily member activin A acts with BDNF and erythropoietin to improve survival of spiral ganglion neurons in vitro

(2013) Odett Kaiser et al.   NEUROPHARMACOLOGY

The use of Neurotrophin Therapy in the Inner Ear to Augment Cochlear Implantation Outcomes

(2012) Cameron L. Budenz et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

The Trk A, B, C's of Neurotrophins in the Cochlea

(2012) Steven H. Green et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

7,8,3′-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo

(2012) Qing Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Developmental changes in the responsiveness of rat spiral ganglion neurons to neurotrophic factors in dissociated culture: differential responses for survival, neuritogenesis and neuronal morphology

(2012) Yulian Jin et al.   CELL AND TISSUE RESEARCH

Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM)

(2012) Sara Euteneuer et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?

(2011) Sune Skeldal et al.   BIOESSAYS

Ras/p38 and PI3K/Akt but not Mek/Erk signaling mediate BDNF-induced neurite formation on neonatal cochlear spiral ganglion explants

(2011) Lina M. Mullen et al.   BRAIN RESEARCH

The spiral ganglion: Connecting the peripheral and central auditory systems

(2011) Bryony A. Nayagam et al.   HEARING RESEARCH

Identification of a low–molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice

(2011) Maxime Cazorla et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I vs type II spiral ganglion neurons exhibit differential survival and neuritogenesis during cochlear development

(2011) Meagan Barclay et al.   Neural Development

Pharmacological characterization of six trkB antibodies reveals a novel class of functional agents for the study of the BDNF receptor

(2010) M Cazorla et al.   BRITISH JOURNAL OF PHARMACOLOGY

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

A Synthetic 7,8-Dihydroxyflavone Derivative Promotes Neurogenesis and Exhibits Potent Antidepressant Effect

(2010) Xia Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Artemin improves survival of spiral ganglion neurons in vivo and in vitro

(2010) Athanasia Warnecke et al.   NEUROREPORT

Cyclotraxin-B, the First Highly Potent and Selective TrkB Inhibitor, Has Anxiolytic Properties in Mice

(2010) Maxime Cazorla et al.   PLoS One

Deoxygedunin, a Natural Product with Potent Neurotrophic Activity in Mice

(2010) Sung-Wuk Jang et al.   PLoS One

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

(2010) S.-W. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Neurotrophic Factors on Growth and Glial Cell Alignment of Cultured Adult Spiral Ganglion Cells

(2009) Marja Boström et al.   AUDIOLOGY AND NEURO-OTOLOGY

Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth

(2009) Michael R. Douglas et al.   BRAIN

Cochlear implants: A remarkable past and a brilliant future

(2008) Blake S. Wilson et al.   HEARING RESEARCH

Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole/BDNF-coated electrodes

(2008) Alison J. Evans et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A