Article
Chemistry, Multidisciplinary
Hao Zhao, Xieli Zhang, Yanxia Qin, Yong Xia, Xin Xu, Xiguang Sun, Dehai Yu, Samuel M. Mugo, Dong Wang, Qiang Zhang
Summary: An integrated wearable sweat-sensing patch is demonstrated for continuous analysis of stress biomarkers at rest. It utilizes a microfluidic chip for sweat collection without perspiration assistance and has a ternary composite electrode for high sensitivity to trace stress biomarkers. The on-site signal processing circuitry enables signal transduction, conditioning, processing, and wireless transmission, with the detection results displayed on a smartphone through software.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Review
Chemistry, Physical
Shujia Xu, Pedro Henrique de Souza Barbosa, Wenzhuo Wu
Summary: Rapid advancements in artificial intelligence, robotics, and remote healthcare have created a demand for sustainable and high-performance wearable sensors. Triboelectric devices, specifically skin-interfaced triboelectric sensors (SITS), are gaining popularity for their operation capability and potential as wearable energy harvesters. This review focuses on the recent advancements of SITS made from biocompatible polymer materials and highlights their potential applications in human-machine interface (HMI) and physiological sensing. The fundamentals, challenges, and prospects of SITS based on biocompatible polymers are also discussed.
Article
Chemistry, Multidisciplinary
Joohee Kim, Yixin Wu, Haiwen Luan, Da Som Yang, Donghwi Cho, Sung Soo Kwak, Shanliangzi Liu, Hanjun Ryu, Roozbeh Ghaffari, John A. Rogers
Summary: A miniaturized system is presented in this study for simple and rapid measurement of multiple essential nutrients in sweat. The system allows for passive and sustained delivery of these nutrients to the body. Results show correlations between the concentrations of nutrients in sweat and blood, highlighting the practical potential of this system for monitoring nutritional balance.
Article
Biophysics
Gopi Karuppaiah, Min-Ho Lee, Shekhar Bhansali, Pandiaraj Manickam
Summary: Psychological stress plays a significant role in health disparities among individuals, and the release of cortisol is a crucial response to stress. Electrochemical sensing has emerged as a reliable method for cortisol detection, and this review focuses on the progress made in electrochemical sensors, their design, principles, and analytical methodologies. The challenges faced in the development of electrochemical cortisol sensors are also discussed, highlighting the need for more sensitive electrodes and materials.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Chemistry, Multidisciplinary
Xiufeng Wang, Yangchengyi Liu, Huanyu Cheng, Xiaoping Ouyang
Summary: This review highlights the importance of rational design of surface wettability in skin-interfaced sensors and devices to maintain device integrity and enhance sensing performance. Various bioinspired strategies have been used to engineer desired surface wettability for different hydrated conditions. Controlling the liquid behavior on device surfaces through surface wettability design allows for effective collection and analysis of health biomarkers, as well as improved performance of energy harvesters.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Supriya Das, Rajan Singh, Avijit Das, Sudipta Bag, Roy P. Paily, Uttam Manna
Summary: A flexible strain sensor with ultrahigh sensitivity and durability at low applied strain has yet to be introduced in the literature. The study presents a novel metal-free, chemically reactive and conductive ink, integrated with chemically reactive porous paper to develop a abrasion tolerant superhydrophobic & conductive patterned interface for achieving a low-strain flexible strain sensor with ultrahigh sensitivity (gauge factor similar to 18 300) and low response time (8 ms). The flexible and durable interface allows for real-time and wireless monitoring of human motions and expressions under diverse conditions, including continuous aqueous exposures and physical abrasions.
MATERIALS HORIZONS
(2021)
Article
Engineering, Electrical & Electronic
Chiara Romano, Domenico Formica, Emiliano Schena, Carlo Massaroni
Summary: This study investigates the influence of sensor placement for cardiorespiratory monitoring using inertial measurement units (IMUs). Triaxial accelerometer data was collected from 15 healthy volunteers in different postures, and the most informative axis and sensor position were determined. The general-purpose configuration allows accurate estimation of respiratory rate (RR) and heart rate (HR), while the posture-dependent configuration improves RR estimation, especially during walking and standing.
IEEE SENSORS JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
Tamoghna Saha, Rafael Del Cano, Ernesto la De Paz, Samar S. Sandhu, Joseph Wang
Summary: Sweat is an important biofluid that regulates body temperature and contains biomarkers similar to those found in blood. This review provides a comprehensive report on approaches to collect and sense sweat from the skin, as well as discusses the advances and applications of sweat sensing technology.
Review
Chemistry, Multidisciplinary
Jehyung Ok, Sumin Park, Yei Hwan Jung, Tae-il Kim
Summary: Wearable and implantable electronic devices have been developed to continuously monitor and analyze the concentration of cortisol, a hormone released in response to stress. These devices provide wireless real-time analysis, overcoming the limitations of traditional cortisol measurement methods. This technology holds great potential for stress monitoring and management.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Saurabh Khuje, Abdullah Islam, Jian Yu, Shenqiang Ren
Summary: This article presents a flexible and wireless multimodal sensor for temperature, pressure, and flow monitoring, fabricated using low-temperature additive manufacturing of copper nanoplates on elastic polyurethane substrates. The sensor exhibits high sensitivity, capable of detecting small pressures and velocities, and features a self-powered, battery-free system with superior real-time sensing performance.
Article
Chemistry, Multidisciplinary
Siyoung Lee, Junsoo Kim, Hajung Roh, Woongji Kim, Sein Chung, Wonkyu Moon, Kilwon Cho
Summary: A skin-attachable acoustic sensor with high sensing accuracy and a wide auditory range is presented in this study. It maintains high sound-detection quality on flexible substrates and in a wide temperature range. The sensor shows significant potential for auditory electronic skin.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jinpeng Wang, Yongkang Qi, Yuhan Gui, Can Wang, Yikai Wu, Jiandong Yao, Jie Wang
Summary: Conductive hydrogel microfibers with high mechanical strength are designed via microfluidics in a one-step manner. By integrating the microfluidics with 3D printing technology, ultrastretchable electronic skin (e-skin) based on conductive hydrogel microfibers can be constructed. Benefiting from the impressive stretching and sensitivity, the e-skin realizes attractive application values in motion monitoring and gesture recognition.
Article
Chemistry, Multidisciplinary
Shaghayegh Shajari, Razieh Salahandish, Azam Zare, Mohsen Hassani, Shirin Moossavi, Emily Munro, Ruba Rashid, David Rosenegger, Jaideep S. S. Bains, Amir Sanati Nezhad
Summary: Stress has significant impacts on cognition, behavior, and physiology, but the ability to detect and measure stress is limited. This study presents a reliable device, MicroSweat, for collecting sweat from different body locations and using cortisol levels as a biomarker for monitoring stress levels. The research reveals a nonlinear correlation between cortisol concentration and perceived stress levels. Moreover, the longitudinal and personalized profiles of sweat cortisol can be obtained, providing crucial data for analyzing human stress in personalized and clinical healthcare sectors.
Review
Chemistry, Multidisciplinary
Kaylee M. Clark, Tyler R. Ray
Summary: Recent advances in skin-interfaced wearable sweat sensors enable the noninvasive, real-time monitoring of biochemical signals associated with health and wellness. This holds significant promise for low-cost, continuous personalized health monitoring and addressing healthcare challenges.
Article
Chemistry, Analytical
Isaia Andrenacci, Riccardo Boccaccini, Alice Bolzoni, Giulio Colavolpe, Cosimo Costantino, Michelangelo Federico, Alessandro Ugolini, Armando Vannucci
Summary: The study compared different inertial sensors for evaluating gait and jump behavior and found that some sensors can reliably be used to identify gait and jump phases, and even detect anomalies.
Article
Biophysics
Brandon K. Ashley, Matthew S. Brown, Youjoong Park, Sally Kuan, Ahyeon Koh
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Chemistry, Physical
Maedeh Mohammadifar, Mehdi Tahernia, Ji Hyun Yang, Ahyeon Koh, Seokheun Choi
Article
Materials Science, Multidisciplinary
Matthew S. Brown, Melissa Mendoza, Poorya Chavoshnejad, Mir Jalil Razavi, Gretchen J. Mahler, Ahyeon Koh
ADVANCED MATERIALS TECHNOLOGIES
(2020)
Article
Chemistry, Multidisciplinary
Ethan Tu, Paul Pearlmutter, Michelle Tiangco, Gia Derose, Lina Begdache, Ahyeon Koh
Article
Nanoscience & Nanotechnology
Arghya K. Bishal, Nickolas D. Anderson, Sai Ken Ho Hung, Jacob R. Jokisaari, Robert F. Klie, Ahyeon Koh, Wildan Abdussalam, Cortino Sukotjo, Christos G. Takoudis
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Chemistry, Physical
Benjamin Heo, Michael Fiola, Ji Hyun Yang, Ahyeon Koh
COLLOID AND INTERFACE SCIENCE COMMUNICATIONS
(2020)
Article
Computer Science, Artificial Intelligence
Jayanth Sivakumar, Ji Hyun Yang, Matthew S. Kelly, Ahyeon Koh, Daehan Won
Summary: This study proposes an automated framework for addressing the challenges of wearable lateral flow assay (LFA) devices on smartphones through image processing steps. The framework accurately identifies wearable sensors under various conditions and detects biomarker lines in the LFA. A strategy to handle reflection and different illumination conditions improves the sensitivity of the framework, which uses real-time images for analysis.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Article
Multidisciplinary Sciences
Matthew S. Brown, Louis Somma, Melissa Mendoza, Yeonsik Noh, Gretchen J. Mahler, Ahyeon Koh
Summary: This study presents a method to upcycle compact discs into flexible and stretchable bio-electronics, providing a sustainable solution to the global issue of electronic waste.
NATURE COMMUNICATIONS
(2022)
Article
Environmental Sciences
Lina Begdache, Saloumeh Sadeghzadeh, Paul Pearlmutter, Gia Derose, Pragna Krishnamurthy, Ahyeon Koh
Summary: The study found that diet quality and physical fitness have a significant impact on saliva cortisol, mood, and mental distress. There are differences between weekdays and weekends. Diet quality and obesity are associated with saliva cortisol levels and mental distress.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Chemistry, Multidisciplinary
Matthew S. Brown, Karen Browne, Nancy Kirchner, Ahyeon Koh
Summary: The wound healing process is not well understood, and chronic wounds have high morbidity and mortality rates. Current strategies for wound assessment and treatment often rely on static wound dressings that do not consider the dynamic physicochemical microenvironment. This study developed an adhesive-free, permeable, and multiplex sensor system for smart bandages that can monitor chemical and physical changes in real-time. The platform provides a conformal, adhesive-free, and convective wound exudate flow, allowing for unobstructed physical and chemical sensor monitoring at the wound site.
Article
Chemistry, Analytical
Ji Hyun Yang, Uchechukwu David, Yeon Sik Noh, Ahyeon Koh
Summary: This article introduces a soft-bioelectronic platform for collecting sweat using a thermal expansion valve under programmed time control. The human study demonstrates that this novel sweat collection device improves sweat analyte data and shows a correlation between sweat rate and lactate levels during aerobic and anaerobic exercises. This approach can be integrated with other chemical sensing modalities for advanced on-board diagnostics.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Multidisciplinary
Joab S. Dorsainvil, Matthew S. Brown, Zahra Rafiee, Anwar Elhadad, Seokheun Choi, Ahyeon Koh
Summary: This paper reports the development of a breathable, lightweight, and biocompatible stretchable paper for unconventional bioelectronic substrates. The stretchable paper is fabricated through coaxial electrospinning of cellulose acetate polymer and silicone elastomer, providing bioconformability without the need for adhesive. The resulting cellulose-silicone fibers exhibit a high percent strain and retain the natural characteristics of paper. It can be used for biosensing, energy generation and storage, and soft actuators, and is compatible with conventional printing and fabrication processes.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Multidisciplinary Sciences
Paul Pearlmutter, Gia DeRose, Cheyenne Samson, Nicholas Linehan, Yuqiao Cen, Lina Begdache, Daehan Won, Ahyeon Koh
SCIENTIFIC REPORTS
(2020)
Proceedings Paper
Optics
Ethan Tu, Lina Begdache, Daehan Won, Ahyeon Koh
2019 IEEE RESEARCH AND APPLICATIONS OF PHOTONICS IN DEFENSE CONFERENCE (RAPID)
(2019)
