Grimace Scores: Tools to Support the Identification of Pain in Mammals Used in Research

Use of the horse grimace scale to identify and quantify pain due to dental disorders in horses

(2020) Mariana Marcantonio Coneglian et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

A Review of Pain Assessment Methods in Laboratory Rodents

(2020) Patricia V Turner et al.   COMPARATIVE MEDICINE

Evoked and spontaneous pain assessment during tooth pulp injury

(2020) Heather Lynn Rossi et al.   Scientific Reports

Is the Piglet Grimace Scale (PGS) a Useful Welfare Indicator to Assess Pain after Cryptorchidectomy in Growing Pigs?

(2020) Cecilia Vullo et al.   Animals

Towards a fully automated surveillance of well-being status in laboratory mice using deep learning: Starting with facial expression analysis

(2020) Niek Andresen et al.   PLoS One

The revised International Association for the Study of Pain definition of pain

(2020) Srinivasa N. Raja et al.   PAIN

Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale

(2019) Chulmin Cho et al.   Scientific Reports

Influence of Rater Training on Inter- and Intrarater Reliability When Using the Rat Grimace Scale

(2019) Emily Q Zhang et al.   Journal of the American Association for Laboratory Animal Science

Facial expression of pain in Nellore and Crossbred beef cattle

(2019) Bruno Roberto Müller et al.   Journal of Veterinary Behavior-Clinical Applications and Research

Conceptual and methodological issues relating to pain assessment in mammals: The development and utilisation of pain facial expression scales

(2019) Krista M. McLennan et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Improvement of the Mouse Grimace Scale set-up for implementing a semi-automated Mouse Grimace Scale scoring (Part 1)

(2019) Lisa Ernst et al.   LABORATORY ANIMALS

The Study of Pain in Rats and Mice

(2019) Christina M Larson et al.   COMPARATIVE MEDICINE

Facial expressions of pain in cats: the development and validation of a Feline Grimace Scale

(2019) Marina C. Evangelista et al.   Scientific Reports

Rodent analgesia: Assessment and therapeutics

(2018) Paul Flecknell   VETERINARY JOURNAL

Can grimace scales estimate the pain status in horses and mice? A statistical approach to identify a classifier

(2018) Emanuela Dalla Costa et al.   PLoS One

Grading facial expression is a sensitive means to detect grimace differences in orofacial pain in a rat model

(2018) Megan M. Sperry et al.   Scientific Reports

Efficacy of buprenorphine for management of surgical castration pain in piglets

(2018) Abbie V. Viscardi et al.   BMC Veterinary Research

Objective pain assessment in horses (2014–2018)

(2018) J.P.A.M. van Loon et al.   VETERINARY JOURNAL

Protecting Animals and Enabling Research in the European Union: An Overview of Development and Implementation of Directive 2010/63/EU

(2017) I Anna S Olsson et al.   ILAR JOURNAL

Do Different Emotional States Affect the Horse Grimace Scale Score? A Pilot Study

(2017) Emanuela Dalla Costa et al.   JOURNAL OF EQUINE VETERINARY SCIENCE

Application of the Rat Grimace Scale as a Marker of Supraspinal Pain Sensation after Cervical Spinal Cord Injury

(2017) Lonnie E. Schneider et al.   JOURNAL OF NEUROTRAUMA

Local anaesthetic refinement of pentobarbital euthanasia reduces abdominal writhing without affecting immunohistochemical endpoints in rats

(2017) Shaun Y-S Khoo et al.   LABORATORY ANIMALS

The composition and initial evaluation of a grimace scale in ferrets after surgical implantation of a telemetry probe

(2017) Marsinah L. Reijgwart et al.   PLoS One

Monitoring equine head-related pain with the Equine Utrecht University scale for facial assessment of pain (EQUUS-FAP)

(2017) Johannes P.A.M. van Loon et al.   VETERINARY JOURNAL

Facial expression: An under-utilised tool for the assessment of welfare in mammals

(2017) Kris Descovich   ALTEX-Alternatives to Animal Experimentation

Methods Used to Evaluate Pain Behaviors in Rodents

(2017) Jennifer R. Deuis et al.   Frontiers in Molecular Neuroscience

The Sheep Grimace Scale as an indicator of post-operative distress and pain in laboratory sheep

(2017) C. Häger et al.   PLoS One

Using the mouse grimace scale and behaviour to assess pain in CBA mice following vasectomy

(2016) Amy L. Miller et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Development of a facial expression scale using footrot and mastitis as models of pain in sheep

(2016) Krista M. McLennan et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Use of Qualitative Behaviour Assessment as an indicator of welfare in donkeys

(2016) Michela Minero et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Coding and quantification of a facial expression for pain in lambs

(2016) M.J. Guesgen et al.   BEHAVIOURAL PROCESSES

Quantification of pain in sickle mice using facial expressions and body measurements

(2016) Aditya Mittal et al.   BLOOD CELLS MOLECULES AND DISEASES

Methods for measuring pain in laboratory animals

(2016) Dustin M. Graham et al.   LAB ANIMAL

The effect of handling method on the mouse grimace scale in two strains of laboratory mice

(2016) Amy L Miller et al.   LABORATORY ANIMALS

Effects and underlying mechanisms of endotoxemia on post-incisional pain in rats

(2016) Takashi Kawano et al.   LIFE SCIENCES

The Influence of Isoflurane Anaesthesia on the Rat Grimace Scale

(2016) Amy L. Miller et al.   PLoS One

Evaluation of Using Behavioural Changes to Assess Post-Operative Pain in the Guinea Pig (Cavia porcellus)

(2016) Yvette Ellen et al.   PLoS One

Effects of fentanyl on pain and motor behaviors following a collagenase-induced intracerebral hemorrhage in rats

(2016) Laurence Saine et al.   Journal of Pain Research

Using the Horse Grimace Scale (HGS) to Assess Pain Associated with Acute Laminitis in Horses (Equus caballus)

(2016) Emanuela Dalla Costa et al.   Animals

Facial Indicators of Positive Emotions in Rats

(2016) Kathryn Finlayson et al.   PLoS One

Lubricin/Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro

(2016) S.M. Iqbal et al.   Scientific Reports

Pain evaluation in dairy cattle

(2015) Karina Bech Gleerup et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

The role of periodontal ASIC3 in orofacial pain induced by experimental tooth movement in rats

(2015) Meiya Gao et al.   EUROPEAN JOURNAL OF ORTHODONTICS

The relationship between the Rat Grimace Scale and mechanical hypersensitivity testing in three experimental pain models

(2015) D. De Rantere et al.   EUROPEAN JOURNAL OF PAIN

Meloxicam prevents COX-2-mediated post-surgical inflammation but not pain following laparotomy in mice

(2015) J.V. Roughan et al.   EUROPEAN JOURNAL OF PAIN

Refinement of analgesia following thoracotomy and experimental myocardial infarction using the Mouse Grimace Scale

(2015) Kiterie M. E. Faller et al.   EXPERIMENTAL PHYSIOLOGY

Using the facial grimace scale to evaluate rabbit wellness in post-procedural monitoring

(2015) Victoria Hampshire et al.   LAB ANIMAL

Postoperative pain in Sprague Dawley rats after liver biopsy by laparotomy versus laparoscopy

(2015) Liette Préfontaine et al.   LAB ANIMAL

Effects of acute chemotherapy-induced mucositis on spontaneous behaviour and the grimace scale in laboratory rats

(2015) A L Whittaker et al.   LABORATORY ANIMALS

Periodontal CGRP contributes to orofacial pain following experimental tooth movement in rats

(2015) Hu Long et al.   NEUROPEPTIDES

The role of TRPA1 in muscle pain and mechanical hypersensitivity under inflammatory conditions in rats

(2015) J. Asgar et al.   NEUROSCIENCE

Ontogeny and phylogeny of facial expression of pain

(2015) Christine T. Chambers et al.   PAIN

An equine pain face

(2015) Karina B Gleerup et al.   VETERINARY ANAESTHESIA AND ANALGESIA

Monitoring acute equine visceral pain with the Equine Utrecht University Scale for Composite Pain Assessment (EQUUS-COMPASS) and the Equine Utrecht University Scale for Facial Assessment of Pain (EQUUS-FAP): A scale-construction study

(2015) Johannes P.A.M. van Loon et al.   VETERINARY JOURNAL

The Mouse Grimace Scale: A Clinically Useful Tool?

(2015) Amy L. Miller et al.   PLoS One

Defining and assessing animal pain

(2014) Lynne U. Sneddon et al.   ANIMAL BEHAVIOUR

Evaluation of pain in rats through facial expression following experimental tooth movement

(2014) Lina Liao et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Effects of ketoprofen for prevention of postoperative cognitive dysfunction in aged rats

(2014) Takashi Kawano et al.   Journal of Anesthesia

Using the mouse grimace scale to assess pain associated with routine ear notching and the effect of analgesia in laboratory mice

(2014) AL Miller et al.   LABORATORY ANIMALS

Development of the Horse Grimace Scale (HGS) as a Pain Assessment Tool in Horses Undergoing Routine Castration

(2014) Emanuela Dalla Costa et al.   PLoS One

Psychometric Assessment of the Rat Grimace Scale and Development of an Analgesic Intervention Score

(2014) Vanessa Oliver et al.   PLoS One

Use of spontaneous behaviour measures to assess pain in laboratory rats and mice: How are we progressing?

(2013) Alexandra L. Whittaker et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Pain assessment in animals

(2013) Jacky Reid et al.   IN PRACTICE

Assessment of postsurgical distress and pain in laboratory mice by nest complexity scoring

(2013) Paulin Jirkof et al.   LABORATORY ANIMALS

Postoperative pain impairs subsequent performance on a spatial memory task via effects on N-methyl-d-aspartate receptor in aged rats

(2013) Haidong Chi et al.   LIFE SCIENCES

Identifying and monitoring pain in farm animals: a review

(2012) A. Prunier et al.   Animal

Minimising pain in farm animals: the 3S approach – ‘Suppress, Substitute, Soothe’

(2012) R. Guatteo et al.   Animal

Facial expressions of mice in aggressive and fearful contexts

(2012) Erwin B. Defensor et al.   PHYSIOLOGY & BEHAVIOR

The Assessment of Post-Vasectomy Pain in Mice Using Behaviour and the Mouse Grimace Scale

(2012) Matthew C. Leach et al.   PLoS One

Evaluation of EMLA Cream for Preventing Pain during Tattooing of Rabbits: Changes in Physiological, Behavioural and Facial Expression Responses

(2012) Stephanie C. J. Keating et al.   PLoS One

Are We Looking in the Wrong Place? Implications for Behavioural-Based Pain Assessment in Rabbits (Oryctolagus cuniculi) and Beyond?

(2011) Matthew C. Leach et al.   PLoS One

A guide to defining and implementing protocols for the welfare assessment of laboratory animals: eleventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement

(2010) P Hawkins et al.   LABORATORY ANIMALS

Coding of facial expressions of pain in the laboratory mouse

(2010) Dale J Langford et al.   NATURE METHODS

Behavioural effects of ovariohysterectomy and oral administration of meloxicam in laboratory housed rabbits

(2009) Matthew C. Leach et al.   RESEARCH IN VETERINARY SCIENCE