Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application

Artesunate-heparin conjugate based nanocapsules with improved pharmacokinetics to combat malaria

(2019) Muhammad Ismail et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Novel method for the determination of average molecular weight of natural polymers based on 2D DOSY NMR and chemometrics: Example of heparin

(2018) Yulia B. Monakhova et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Inhibition of merozoite invasion and transient de-sequestration by sevuparin in humans with Plasmodium falciparum malaria

(2017) Anna M. Leitgeb et al.   PLoS One

Exploitation of a newly-identified entry pathway into the malaria parasite-infected erythrocyte to inhibit parasite egress

(2017) Svetlana Glushakova et al.   Scientific Reports

A fluorescent probe assay (Heparin Red) for direct detection of heparins in human plasma

(2016) U. Warttinger et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Giant Host Red Blood Cell Membrane Mimicking Polymersomes Bind Parasite Proteins and Malaria Parasites

(2016) Adrian Najer et al.   CHIMIA

Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium

(2016) Joana Marques et al.   Scientific Reports

Improving oral drug bioavailability with polycations?

(2015) Jessica D. Schulz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting

(2015) Davide Angeletti et al.   PLoS One

Nanomimics of Host Cell Membranes Block Invasion and Expose Invasive Malaria Parasites

(2014) Adrian Najer et al.   ACS Nano

Application of heparin as a dual agent with antimalarial and liposome targeting activities toward Plasmodium-infected red blood cells

(2014) Joana Marques et al.   Nanomedicine-Nanotechnology Biology and Medicine

Chitosan-based nanomaterials: A state-of-the-art review

(2013) Sudheesh K. Shukla et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Demonstration of specific binding of heparin to Plasmodium falciparum-infected vs. non-infected red blood cells by single-molecule force spectroscopy

(2012) Juan José Valle-Delgado et al.   Nanoscale

Low Anticoagulant Heparin Disrupts Plasmodium falciparum Rosettes in Fresh Clinical Isolates

(2011) Anna M. Leitgeb et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

(2010) M. J. Boyle et al.   BLOOD

Biochemical and biophysical characterisation of DBL1α1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum

(2010) Alexandre Juillerat et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY