Article
Medicine, General & Internal
Jing Peng, Xing Min Han
Summary: This study investigated the characteristics and factors affecting the prognosis of ES/pPNET patients. It was found that the treatment method and metastasis at diagnosis were associated with the survival time of ES/pPNET patients.
Article
Clinical Neurology
Gauri Deshpande, Sridhar Epari, Chhavi Gupta, Omshree Shetty, Mamta Gurav, Girish Chinnaswamy, Tejpal Gupta
Summary: This report highlights the primary intracranial occurrence of Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) in non-osseous meningeal sites, emphasizing the need to consider ES/PNET in the differential diagnosis of primary intracranial primitive embryonal tumors.
CHILDS NERVOUS SYSTEM
(2021)
Article
Medicine, Research & Experimental
Yu Ye, Xiaoming Qiu, Jixin Mei, Dongyun He, Ailing Zou
Summary: This case involves a 55-year-old woman presenting with fatigue, fever, and black stool, who was diagnosed with primary gastric ES. Treatment included radical distal gastrectomy, with the patient declining chemoradiotherapy.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Article
Oncology
Yuanyuan Wu, Aihong Mao, Jun Wang
Summary: This case report describes a 9-year-old girl with a primary extraskeletal ES/pPNET tumor in the tongue, who achieved tumor-free survival through surgical treatment and chemotherapy.
Article
Surgery
Jun Chen, Shi-Zhou Wu, Jie Tan, Qing-Yi Zhang, Bo-Quan Qin, Yu Wang, Hui Zhang
Summary: This study compared the characteristics, treatment strategies, and outcomes of patients with ES/pPNETs of the cranial bone and those with ES/pPNETs of the mobile spine. The results showed that patients with ES/pPNETs of the cranial bone were younger and had a longer disease duration compared to those with ES/pPNETs of the mobile spine. However, there was no significant difference in the prognosis between the two groups. Complete resection and radiotherapy were found to offer the best prognosis for improved long-term survival.
Article
Urology & Nephrology
Weipu Mao, Jiajia Xu, Haowen Lu, Yali Wang, Lihua Zhang, Ming Chen
Summary: We report an unusual case of ectopic ACTH syndrome and hypothyroidism caused by renal Ewing sarcoma/PNET. The clinical manifestation of renal Ewing sarcoma/PNET is non-specific and the diagnosis relies on pathological morphology, immunohistochemistry, and fusion gene detection.
Article
Obstetrics & Gynecology
Sara E. Bachert, Lauren A. Baldwin, Julie C. Dueber, Dava W. Piecoro
Summary: Primitive neuroectodermal tumors (PNETs) of the ovary are rare and highly aggressive neoplasms. They can be classified as either peripheral or central types. We present a case of a central type ovarian PNET in a young female presenting with a pelvic mass and elevated serum tumor markers.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
(2022)
Article
Oncology
Archana Sasi, Shuvadeep Ganguly, Bivas Biswas, Deepam Pushpam, Akash Kumar, Sandeep Agarwala, Shah Alam Khan, Venkatesan Sampath Kumar, Suryanarayana Deo, Daya Nand Sharma, Ahitagni Biswas, Asit Mridha, Adarsh Barwad, Sanjay Thulkar, Sameer Bakhshi
Summary: A prognostic score for Ewing sarcoma incorporating baseline clinical and laboratory parameters has been formulated and validated in this study. It has fair predictive ability for risk stratification and facilitates risk-adapted personalized therapy.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Article
Clinical Neurology
Jing Zhang, Qiu Sun, Guojin Zhang, Yuntai Cao, Junlin Zhou
Summary: There are significant differences in the MRI features of MCMs and meningeal Ewing sarcoma/pPNETs, including tumor morphology, dural tail sign, bone destruction, and distant metastasis. Immunohistochemistry results show that MCMs are positive for Vim, EMA, and have a Ki-67 index less than 5%, while meningeal Ewing sarcoma/pPNET cases are positive for Vim and CD99, with a Ki-67 index over 30%.
ACTA NEUROLOGICA BELGICA
(2021)
Article
Medicine, General & Internal
Atef A. Rashed, Reem Alharthi, Shuaa Aljabri, Raghad Alsubhi, Deemah H. Bukhari
Summary: A case of peripheral primitive neuroectodermal tumor (PNET) in a five-year-old boy is reported. The patient presented with symptoms of vomiting, abdominal pain, hepatomegaly, and weight loss. The tumor metastasized to the liver and lungs, leading to the patient's death. Early diagnosis and treatment are crucial for improving the survival rate of PNET.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Oncology
Ahmed Mohammed Morsy, Salah Abdel-Hadi, Khalid Mohammed Rezk, Gamal Amira, Badawy Mohammed Ahmed, Marwa Tammam Hussien, Mahmoud Gamal Ameen, Hosam Eldein Mostafa Kamel, Doaa Mohamed Fouad, Alia Mohamed Attia, Asmaa Salah, Osama Mostafa Abd Elbadee, Ayatallah Ali Yousseif, Marwa Ismail Abdelgawad, Asmaa Hussein Fathy, Yasmine Nagy Elwany, Islam Karam-Allah Ramadan, Khaled Hassan Mosallam, Ahmed Ibrahim Abd Elwahab, Khaled Hashim Mahmoud, Maged Abdel Fattah Amine, Ahmed Refaat Abd Elzaher, Hanan Ahmed Eltyb, Ahmed Mubarak Hefni
Summary: This study aimed to evaluate the survival outcomes of Ewing sarcoma in Upper Egypt and identify factors of prognostic significance, showing that metastatic disease, surgery used as a local modality, response to neoadjuvant chemotherapy, and primary tumor size were significantly associated with overall survival. While the 5-year overall survival rate was comparable to previous studies in Egypt, outcomes in Egypt still lag behind internationally published studies due to differences in study samples among research centers.
AMERICAN JOURNAL OF CANCER RESEARCH
(2021)
Review
Clinical Neurology
Abdussamet Batur
Summary: This case report discusses a rare case of primary intracranial Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) that was initially mistaken radiologically as a meningioma. The report emphasizes the importance of distinguishing between these two tumors due to their different treatment and prognosis. MRI perfusion findings were found to be helpful in discrimination.
BRITISH JOURNAL OF NEUROSURGERY
(2023)
Review
Medicine, General & Internal
Mohamed Hedfi, Imen Ben Ismail, Hakim Zenaidi, Sirine Bouslama, Ayoub Zoghlami
Summary: This article reports a rare case of Ewing's sarcoma (ES) occurring in the liver, presenting with abdominal pain. The diagnosis was confirmed through histopathological examination and adjuvant chemotherapy was administered.
CLINICAL CASE REPORTS
(2022)
Article
Medicine, General & Internal
Alije Keka-Sylaj, Atifete Ramosaj, Arbana Baloku, Leonore Zogaj, Flamur Mushica, Fisnik Kurshumliu
Summary: A rare case of peripheral primitive neuroectodermal tumor in a 4-year-old Albanian girl with an unusual clinical presentation is reported. The diagnosis of primitive neuroectodermal tumor was confirmed through histopathology and immunohistochemical examination. This article highlights the importance of considering other solid tumors in the differential diagnosis when musculoskeletal symptoms are present in children.
JOURNAL OF MEDICAL CASE REPORTS
(2022)
Article
Medicine, General & Internal
Taysa Benitez Delgado, Maria Laseca-Modrego, Daniel Gonzalez Garcia-Cano, Andres Rave Ramirez, Octavio Arencibia-Sanchez
Summary: Uterine primitive neuroectodermal tumors (PNETs) are rare and often diagnosed at advanced stages with poor prognosis. There is no optimal chemotherapy regimen for PNET, and further research is needed to improve outcomes.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)