AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions

PKA‐independent vasopressin signaling in renal collecting duct

(2020) Arnab Datta et al.   FASEB JOURNAL

Sorting Nexin 27 Regulates the Lysosomal Degradation of Aquaporin-2 Protein in the Kidney Collecting Duct

(2020) Hyo-Jung Choi et al.   Cells

GENETICS IN ENDOCRINOLOGY Pathophysiology, diagnosis and treatment of familial nephrogenic diabetes insipidus

(2020) Daniel G Bichet   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance

(2019) Sathish Murali et al.   Cells

Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit

(2019) Pui W. Cheung et al.   Annual Review of Pharmacology and Toxicology

Identification of UT-A1- and AQP2-interacting proteins in rat inner medullary collecting duct

(2018) Chung-Lin Chou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus

(2018) Fumiaki Ando et al.   Nature Communications

Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2–Mediated Water Homeostasis

(2018) Suchun Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ezrin directly interacts with AQP2 and promotes its endocytosis

(2017) Wei Li et al.   JOURNAL OF CELL SCIENCE

NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation

(2017) Christiane Trimpert et al.   PLoS One

Renal aquaporins and water balance disorders

(2016) Hanne B. Moeller et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Comprehensive database of human E3 ubiquitin ligases: application to aquaporin-2 regulation

(2016) Barbara Medvar et al.   PHYSIOLOGICAL GENOMICS

Rosiglitazone Promotes AQP2 Plasma Membrane Expression In Renal Cells Via a Ca2+-Dependent/cAMP-Independent Mechanism

(2015) Giuseppe Procino et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study

(2015) Alejandro García Castaño et al.   EUROPEAN JOURNAL OF PEDIATRICS

Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and -ζ

(2015) Hanne B. Moeller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Partial nephrogenic diabetes insipidus caused by a novel AQP2 variation impairing trafficking of the aquaporin-2 water channel

(2015) Pia Dollerup et al.   BMC Nephrology

Phosphorylation and ubiquitylation are opposing processes that regulate endocytosis of the water channel aquaporin-2

(2014) H. B. Moeller et al.   JOURNAL OF CELL SCIENCE

Novel AQP2 mutation causing congenital nephrogenic diabetes insipidus: challenges in management during infancy

(2013) Rottanat Rugpolmuang et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Aqp2-Expressing Cells Give Rise to Renal Intercalated Cells

(2013) H. Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aqp5 Is a New Transcriptional Target of Dot1a and a Regulator of Aqp2

(2013) Hongyu Wu et al.   PLoS One

Close Association of Aquaporin-2 Internalization with Caveolin-1

(2012) Takeo Aoki et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Hereditary nephrogenic diabetes insipidus in Japanese patients: analysis of 78 families and report of 22 new mutations in AVPR2 and AQP2

(2012) Sei Sasaki et al.   Clinical and Experimental Nephrology

Novel compound aquaporin 2 mutations in nephrogenic diabetes insipidus

(2012) RD Liberatore-Jr et al.   Clinics

Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus

(2011) E. T. B. Olesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New autosomal recessive mutations in aquaporin-2 causing nephrogenic diabetes insipidus through deficient targeting display normal expression inXenopusoocytes

(2010) Alexandre Leduc-Nadeau et al.   JOURNAL OF PHYSIOLOGY-LONDON

Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration

(2010) R. Bouley et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Novel Mutation of Aquaporin-2 Gene in a Patient with Congenital Nephrogenic Diabetes Insipidus

(2009) Seong-Su MOON et al.   ENDOCRINE JOURNAL

p.R254Q mutation in the aquaporin-2 water channel causing dominant nephrogenic diabetes insipidus is due to a lack of arginine vasopressin-induced phosphorylation

(2009) Paul JM Savelkoul et al.   HUMAN MUTATION

Identification of Phosphorylation-Dependent Binding Partners of Aquaporin-2 Using Protein Mass Spectrometry

(2009) Nicholas A. Zwang et al.   JOURNAL OF PROTEOME RESEARCH

LIP5 Interacts with Aquaporin 2 and Facilitates Its Lysosomal Degradation

(2009) B. W.M. van Balkom et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions

(2009) H. B. Moeller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vasopressin-stimulated Increase in Phosphorylation at Ser269Potentiates Plasma Membrane Retention of Aquaporin-2

(2008) Jason D. Hoffert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKAP220 colocalizes with AQP2 in the inner medullary collecting ducts

(2008) Rie Okutsu et al.   KIDNEY INTERNATIONAL

Aquaporin 2 Mutations in Nephrogenic Diabetes Insipidus

(2008) Anne J.M. Loonen et al.   SEMINARS IN NEPHROLOGY