Tumor Treating Fields (TTFields) Hinder Cancer Cell Motility through Regulation of Microtubule and Actin Dynamics

Tumor-treating fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy

(2020) Tali Voloshin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Global post-marketing safety surveillance of Tumor Treating Fields (TTFields) in patients with high-grade glioma in clinical practice

(2020) Wenyin Shi et al.   JOURNAL OF NEURO-ONCOLOGY

A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions

(2019) Nisha Bte Mohd Rafiq et al.   NATURE MATERIALS

RhoA as a Key Regulator of Innate and Adaptive Immunity

(2019) Bros et al.   Cells

Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA

(2017) Yaming Jiu et al.   JOURNAL OF CELL SCIENCE

Biological activity of tumor-treating fields in preclinical glioma models

(2017) Manuela Silginer et al.   Cell Death & Disease

Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)

(2017) Yaara Porat et al.   Jove-Journal of Visualized Experiments

Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis

(2016) Eun Ho Kim et al.   Oncotarget

Tumor Treating Fields Perturb the Localization of Septins and Cause Aberrant Mitotic Exit

(2015) Nidhi Gera et al.   PLoS One

Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells

(2015) Moshe Giladi et al.   Scientific Reports

Electrophoresis of Cellular Membrane Components Creates the Directional Cue Guiding Keratocyte Galvanotaxis

(2013) Greg M. Allen et al.   CURRENT BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization

(2011) Christopher M. Hale et al.   JOURNAL OF CELL SCIENCE

Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs

(2009) Eilon D. Kirson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Lung cancer A549 cells migrate directionally in DC electric fields with polarized and activated EGFRs

(2008) Xiaolong Yan et al.   BIOELECTROMAGNETICS

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubule curvatures under perpendicular electric forces reveal a low persistence length

(2008) M. G. L. Van den Heuvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA