4.7 Article

No-Reflow after PPCI-A Predictor of Short-Term Outcomes in STEMI Patients

Journal

JOURNAL OF CLINICAL MEDICINE
Volume 9, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/jcm9092956

Keywords

acute myocardial infarction (MI); no-reflow phenomenon (NRP); primary percutaneous coronary intervention (PPCI); thrombolysis in myocardial infarction (TIMI) risk score

Funding

  1. European Social Fund through The Human Capital Operational Program 2014-2020 [123008]

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The no-reflow phenomenon following primary percutaneous coronary intervention (PPCI) in acute ST-elevation myocardial infarction (STEMI) patients is a predictor of unfavorable prognosis. Patients with no-reflow have many complications during admission, and it is considered a marker of short-term mortality. The current research emphasizes the circumstances of the incidence and complications of the no-reflow phenomenon in STEMI patients, including in-hospital mortality. In this case-control study, conducted over two and a half years, there were enrolled 656 patients diagnosed with STEMI and reperfused through PPCI. Several patients (n= 96) developed an interventional type of no-reflow phenomenon. One third of the patients with a no-reflow phenomenon suffered complications during admission, and 14 succumbed. Regarding complications, the majority consisted of arrhythmias (21.68%) and cardiogenic shock (16.67%). The anterior localization of STEMI and the left anterior descending artery (LAD) as a culprit lesion were associated with the highest number of complications during hospitalization. At the same time, the time interval >12 h from the onset of the typical symptoms of myocardial infarction (MI) until revascularization, as well as multiple stents implantations during PPCI, correlated with an increased incidence of short-term complications. The no-reflow phenomenon in patients with STEMI was associated with an unfavorable short-term prognosis.

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