Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys

Title
Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys
Authors
Keywords
α-Synuclein, Antisense oligonucleotide, Axonal neurodegeneration, Dopamine neurotransmission, Mouse and monkey models, Parkinson's disease
Journal
EBioMedicine
Volume 59, Issue -, Pages 102944
Publisher
Elsevier BV
Online
2020-08-15
DOI
10.1016/j.ebiom.2020.102944

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