Nanoemulsion adjuvantation strategy of tumor-associated antigen therapy rephrases mucosal and immunotherapeutic signatures following intranasal vaccination

Dual pH-sensitive nanodrug blocks PD-1 immune checkpoint and uses T cells to deliver NF-κB inhibitor for antitumor immunotherapy

(2020) Zecong Xiao et al.   Science Advances

Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos

(2019) Nadège Poncet et al.   EMBO REPORTS

Polysorbasome: A Colloidal Vesicle Contoured by Polymeric Bioresorbable Amphiphiles as an Immunogenic Depot for Vaccine Delivery

(2018) Chiung-Yi Huang et al.   ACS Applied Materials & Interfaces

Unsaturated Squalene Content in Emulsion Vaccine Adjuvants Plays a Crucial Role in ROS-Mediated Antigen Uptake and Cellular Immunity

(2017) Chung-Hsiung Huang et al.   MOLECULAR PHARMACEUTICS

PEGylated squalenoyl-gemcitabine nanoparticles for the treatment of glioblastoma

(2016) Alice Gaudin et al.   BIOMATERIALS

Chimeric peptide containing both B and T cells epitope of tumor-associated antigen L6 enhances anti-tumor effects in HLA-A2 transgenic mice

(2016) Su-I Lin et al.   CANCER LETTERS

Mucosal delivery of a combination adjuvant comprising emulsified fine particles and LD-indolicidin enhances serological immunity to inactivated influenza virus

(2016) Ming-Hsi Huang et al.   MICROBES AND INFECTION

Targeting natural killer cells in cancer immunotherapy

(2016) Camille Guillerey et al.   NATURE IMMUNOLOGY

Use of recombinant flagellin in oil-in-water emulsions enhances hemagglutinin-specific mucosal IgA production and IL-17 secreting T cells against H5N1 avian influenza virus infection

(2015) Chih-Hsuan Lai et al.   VACCINE

Expression of the Activating Receptor, NKp46 (CD335), in Human Natural Killer and T-Cell Neoplasia

(2013) Aharon G. Freud et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Gut homeostasis in a microbial world: insights from Drosophila melanogaster

(2013) Nicolas Buchon et al.   NATURE REVIEWS MICROBIOLOGY

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Generation of Effector Memory T Cell-Based Mucosal and Systemic Immunity with Pulmonary Nanoparticle Vaccination

(2013) A. V. Li et al.   Science Translational Medicine

Intranasal immunization with W805EC adjuvanted recombinant RSV rF-ptn enhances clearance of respiratory syncytial virus in a mouse model

(2013) Crystal Passmore et al.   Human Vaccines & Immunotherapeutics

Self-Assembled Peptide Amphiphile Micelles Containing a Cytotoxic T-Cell Epitope Promote a Protective Immune Response In Vivo

(2012) Matthew Black et al.   ADVANCED MATERIALS

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Intranasal Immunization of Ferrets with Commercial Trivalent Influenza Vaccines Formulated in a Nanoemulsion-Based Adjuvant

(2011) Tarek Hamouda et al.   Clinical and Vaccine Immunology

Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge—an ex vivo and in silico approach

(2011) Julian Kirch et al.   JOURNAL OF CONTROLLED RELEASE

Endogenous IL-17 contributes to reduced tumor growth and metastasis

(2009) I. Kryczek et al.   BLOOD

Vaccine adjuvants: Current challenges and future approaches

(2008) Jennifer H. Wilson-Welder et al.   JOURNAL OF PHARMACEUTICAL SCIENCES