Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma

Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid

(2019) Alexandra M. Miller et al.   NATURE

Genome-wide cell-free DNA fragmentation in patients with cancer

(2019) Stephen Cristiano et al.   NATURE

Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma

(2019) Jiabin Cai et al.   GUT

DNA methylation-based classification of central nervous system tumours

(2018) David Capper et al.   NATURE

Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC

(2018) Jia Li et al.   NUCLEIC ACIDS RESEARCH

Cerebrospinal fluid cell-free tumour DNA as a liquid biopsy for primary brain tumours and central nervous system metastases

(2018) J Seoane et al.   ANNALS OF ONCOLOGY

Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients

(2018) Florent Mouliere et al.   EMBO Molecular Medicine

A pilot study on the use of cerebrospinal fluid cell-free DNA in intramedullary spinal ependymoma

(2017) Ian David Connolly et al.   JOURNAL OF NEURO-ONCOLOGY

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

(2017) Edward C Schwalbe et al.   LANCET ONCOLOGY

The whole-genome landscape of medulloblastoma subtypes

(2017) Paul A. Northcott et al.   NATURE

Childhood medulloblastoma

(2016) Maura Massimino et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid

(2016) Elena I. Pentsova et al.   JOURNAL OF CLINICAL ONCOLOGY

Divergent clonal selection dominates medulloblastoma at recurrence

(2016) A. Sorana Morrissy et al.   NATURE

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

(2016) Charles Y. Lin et al.   NATURE

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

(2015) Kristian W. Pajtler et al.   CANCER CELL

Brain Tumor Mutations Detected in Cerebral Spinal Fluid

(2015) W. Pan et al.   CLINICAL CHEMISTRY

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

(2015) Yuxuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

(2015) Leticia De Mattos-Arruda et al.   Nature Communications

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

(2014) Volker Hovestadt et al.   NATURE

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Connections between TET proteins and aberrant DNA modification in cancer

(2014) Yun Huang et al.   TRENDS IN GENETICS

MOABS: model based analysis of bisulfite sequencing data

(2014) Deqiang Sun et al.   GENOME BIOLOGY

The Role of Chromatin Remodeling in Medulloblastoma

(2013) David T. W. Jones et al.   BRAIN PATHOLOGY

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

(2013) Sebastian Bender et al.   CANCER CELL

Medulloblastoma molecular dissection

(2013) Marc Remke et al.   CURRENT OPINION IN ONCOLOGY

Misdiagnosing recurrent medulloblastoma: the danger of examination and imaging without histological confirmation

(2013) Lauren Weintraub et al.   Journal of Neurosurgery-Pediatrics

Transitioning from genotypes to epigenotypes: Why the time has come for medulloblastoma epigenomics

(2013) N.V. Batora et al.   NEUROSCIENCE

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma

(2012) Adrian M. Dubuc et al.   ACTA NEUROPATHOLOGICA

The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine

(2012) Yun Huang et al.   Nature Protocols

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

(2010) Yun Huang et al.   PLoS One

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

BSMAP: whole genome bisulfite sequence MAPping program

(2009) Yuanxin Xi et al.   BMC BIOINFORMATICS

Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma

(2008) Ulrich Schüller et al.   CANCER CELL

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL