ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule

Glutathione and Reactive Oxygen Species Dual-Responsive Block Copolymer Prodrugs for Boosting Tumor Site-Specific Drug Release and Enhanced Antitumor Efficacy

(2020) Wei Yin et al.   BIOMACROMOLECULES

Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism

(2019) Viridiana Olin-Sandoval et al.   NATURE

Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

(2019) Wenjia Zhang et al.   Nature Communications

Enhanced Antitumor Efficacy by a Cascade of Reactive Oxygen Species Generation and Drug Release

(2019) Sheng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Length effect of stimuli-responsive block copolymer prodrug filomicelles on drug delivery efficiency

(2019) Wendong Ke et al.   JOURNAL OF CONTROLLED RELEASE

Light-Activatable Red Blood Cell Membrane-Camouflaged Dimeric Prodrug Nanoparticles for Synergistic Photodynamic/Chemotherapy

(2018) Qing Pei et al.   ACS Nano

Biodegradable, Hydrogen Peroxide, and Glutathione Dual Responsive Nanoparticles for Potential Programmable Paclitaxel Release

(2018) Daiqin Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury

(2018) Jack L. Martin et al.   PEDIATRIC NEPHROLOGY

Global epidemiology and outcomes of acute kidney injury

(2018) Eric A. J. Hoste et al.   Nature Reviews Nephrology

l-Serine–modified polyamidoamine dendrimer as a highly potent renal targeting drug carrier

(2018) Satoru Matsuura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age

(2017) Mariya T. Sweetwyne et al.   KIDNEY INTERNATIONAL

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

(2017) Nandhini Ponnuswamy et al.   Nature Communications

Diabetes and Kidney Disease: Role of Oxidative Stress

(2016) Jay C. Jha et al.   ANTIOXIDANTS & REDOX SIGNALING

Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

(2016) Satoko Arai et al.   NATURE MEDICINE

Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

(2015) Randy Cheung et al.   Marine Drugs

Sepsis-Associated Acute Kidney Injury

(2015) Rashid Alobaidi et al.   SEMINARS IN NEPHROLOGY

TIMgenes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

(2015) Gordon J. Freeman et al.   IMMUNOLOGICAL REVIEWS

Conjugated-Polyelectrolyte-Based Polyprodrug: Targeted and Image-Guided Photodynamic and Chemotherapy with On-Demand Drug Release upon Irradiation with a Single Light Source

(2014) Youyong Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes

(2014) Lakhmir S. Chawla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Origin of regenerating tubular cells after acute kidney injury

(2014) K. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MLK3 Is Part of a Feedback Mechanism That Regulates Different Cellular Responses to Reactive Oxygen Species

(2014) H.-S. Lee et al.   Science Signaling

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

(2013) Hazel H Szeto   BRITISH JOURNAL OF PHARMACOLOGY

Heme oxygenase-1 and acute kidney injury

(2013) Karl A. Nath   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Strong Adhesion and Cohesion of Chitosan in Aqueous Solutions

(2013) Dong Woog Lee et al.   LANGMUIR

Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage

(2013) Bidya Dhar Sahu et al.   PHYTOMEDICINE

Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats

(2012) Edilia Tapia et al.   Oxidative Medicine and Cellular Longevity

Regulation of Phosphatidylinositol-5-Phosphate Signaling by Pin1 Determines Sensitivity to Oxidative Stress

(2012) W.-J. Keune et al.   Science Signaling

Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury

(2011) H. H. Szeto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis

(2011) Steven G. Coca et al.   KIDNEY INTERNATIONAL

Drug targeting to the kidney: Advances in the active targeting of therapeutics to proximal tubular cells☆

(2010) M.E.M. Dolman et al.   ADVANCED DRUG DELIVERY REVIEWS

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Pathways of renal injury in systemic gram-negative sepsis

(2008) T. M. El-Achkar et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

(2008) Takaharu Ichimura et al.   JOURNAL OF CLINICAL INVESTIGATION

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY