VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription

VGLL4 plays a critical role in heart valve development and homeostasis

(2019) Wei Yu et al.   PLoS Genetics

Dual function of VGLL 4 in muscle regeneration

(2019) Xue Feng et al.   EMBO JOURNAL

H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

(2018) Lijun Wang et al.   PLOS BIOLOGY

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo

(2017) Shilpy Joshi et al.   PLoS Genetics

Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2

(2016) Yoshinori Matsumoto et al.   JOURNAL OF CLINICAL INVESTIGATION

Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation

(2016) Yi Tang et al.   NATURE CELL BIOLOGY

Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development

(2016) Zhen Liu et al.   Nature Communications

Yap1 Regulates Multiple Steps of Chondrocyte Differentiation during Skeletal Development and Bone Repair

(2016) Yujie Deng et al.   Cell Reports

Increased TEAD4 expression and nuclear localization in colorectal cancer promote epithelial–mesenchymal transition and metastasis in a YAP-independent manner

(2015) Y Liu et al.   ONCOGENE

Hippo signaling in epithelial stem cells

(2014) M.-X. Yin et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

Osteogenic fate of hypertrophic chondrocytes

(2014) Guan Yang et al.   CELL RESEARCH

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

(2014) Wenjing Zhang et al.   CELL RESEARCH

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

(2014) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ

(2013) Dulcie Lai et al.   CELLULAR SIGNALLING

Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop

(2012) W.-M. Woo et al.   GENES & DEVELOPMENT

Taxol Resistance in Breast Cancer Cells Is Mediated by the Hippo Pathway Component TAZ and Its Downstream Transcriptional Targets Cyr61 and CTGF

(2011) D. Lai et al.   CANCER RESEARCH

Structural insights into the YAP and TEAD complex

(2010) Z. Li et al.   GENES & DEVELOPMENT

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

(2010) Matthew B. Greenblatt et al.   JOURNAL OF CLINICAL INVESTIGATION

Correlation between genotype and supernumerary tooth formation in cleidocranial dysplasia

(2010) N Suda et al.   Orthodontics & Craniofacial Research

The Hippo–YAP pathway: new connections between regulation of organ size and cancer

(2008) Bin Zhao et al.   CURRENT OPINION IN CELL BIOLOGY

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT