The m6A Methyltransferase METTL3 Is Functionally Implicated in DLBCL Development by Regulating m6A Modification in PEDF

RNA N6-methyladenosine modification in solid tumors: new therapeutic frontiers

(2020) Laleh Melstrom et al.   CANCER GENE THERAPY

METTL3/YTHDF2 m 6 A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer

(2020) Haiyun Xie et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

RBP EIF2S2 Promotes Tumorigenesis and Progression by Regulating MYC-Mediated Inhibition via FHIT-Related Enhancers

(2020) Jiwei Zhang et al.   MOLECULAR THERAPY

METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway

(2020) Dong-Dong Yang et al.   Frontiers in Oncology

Predicting the future for DLBCL

(2020) Bruce D. Cheson   BLOOD

DLBCL subclassification: divide and conquer?

(2020) Ryan D. Morin et al.   BLOOD

An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

(2020) Song Zhu et al.   Nature Communications

Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis

(2020) Josef Leibold et al.   Cancer Discovery

Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled

(2020) Ondrej Bernatik et al.   Cells

Modification of Adenosine196 by Mettl3 Methyltransferase in the 5’-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation

(2020) Olga Sergeeva et al.   Cells

METTL3 regulates the malignancy of cervical cancer via post-transcriptional regulation of RAB2B

(2020) Yingying Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

miR-183-5p Inhibits Occurrence and Progression of Acute Myeloid Leukemia via Targeting Erbin

(2019) Zhuojun Zheng et al.   MOLECULAR THERAPY

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

(2019) Yi Niu et al.   Molecular Cancer

Prognostic impact of natural killer cell count in follicular lymphoma and diffuse large B-cell lymphoma patients treated with immunochemotherapy

(2019) Magdalena Klanova et al.   CLINICAL CANCER RESEARCH

Genetic alterations and their clinical implications in DLBCL

(2019) Yi Miao et al.   Nature Reviews Clinical Oncology

The Role of PEDF in Pancreatic Cancer

(2019) DANIEL ANSARI et al.   ANTICANCER RESEARCH

A Mass Spectrometric Assay of METTL3/METTL14 Methyltransferase Activity

(2019) Shane M. Buker et al.   SLAS Discovery

A Linear Regression Predictor for Identifying N6-Methyladenosine Sites Using Frequent Gapped K-mer Pattern

(2019) Y.Y. Zhuang et al.   Molecular Therapy-Nucleic Acids

Multiple Functions and Mechanisms Underlying the Role of METTL3 in Human Cancers

(2019) Wenhui Zheng et al.   Frontiers in Oncology

PEDF regulates plasticity of a novel lipid–MTOC axis in prostate cancer-associated fibroblasts

(2018) Francesca Nardi et al.   JOURNAL OF CELL SCIENCE

Pigment epithelium-derived factor: a key mediator in bone homeostasis and potential for bone regenerative therapy

(2018) Mia Baxter-Holland et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

M6APred-EL: A sequence-based predictor for identifying N6-methyladenosine sites using ensemble learning

(2018) Leyi Wei et al.   Molecular Therapy-Nucleic Acids

Pigment epithelium-derived factor inhibits lung cancer migration and invasion by upregulating exosomal thrombospondin 1

(2018) Wen-Tsung Huang et al.   CANCER LETTERS

Pigment epithelium-derived factor alleviates endothelial injury by inhibiting Wnt/β-catenin pathway

(2017) Shouyuan Ma et al.   Lipids in Health and Disease

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

(2017) Isaia Barbieri et al.   NATURE

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

(2017) Ly P Vu et al.   NATURE MEDICINE

Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer

(2017) Xiuli Wang et al.   Oncotarget

The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma

(2017) Xiao Li et al.   Oncotarget

Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a Protein-induced Autophagy in Pancreatic Intraepithelial Neoplasms

(2016) Jingjing Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas

(2016) M K Bognar et al.   ONCOGENE

Erbin interacts with c-Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c-Cbl-mediated ubiquitination and down-regulation of EGFR

(2015) Su Yao et al.   JOURNAL OF PATHOLOGY

Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma

(2014) R. Koch et al.   BLOOD

Identification of a Novel Inhibitor of the Canonical Wnt Pathway

(2011) K. Park et al.   MOLECULAR AND CELLULAR BIOLOGY