Journal
CURRENT ORGANIC CHEMISTRY
Volume 20, Issue 14, Pages 1502-1511Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1385272820666151207194453
Keywords
Glyconanoparticles; methodologies; carbohydrate-lectin interactions; biomedicine
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Funding
- Hundred Talents Program of Chinese Academy of Sciences [Y20245YBR1]
- National Natural Science Foundation of China [21402215, 61474124]
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Glyconanoparticles are the subject of numerous literatures and are emerging for applications in biomedicine, glycoscience, and material science due to their unique properties. They are hybrid materials each of which contains a nanoparticle core surrounded by a carbohydrate shell. The core can be metallic, magnetic, and/or photoluminescent, while the shell may be composed of mono-, di-, oligo- and/or poly-saccharides. Sugars are attached to the surface of the nanoparticles through covalent or non-covalent interaction. Here, we give a brief summary of the synthetic methodologies adopted in the preparation of different types of glyconanoparticles, which can be utilized in various applications including catalysis, drug delivery, vaccine, imaging and study of carbohydrate-lectin interactions.
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