A map of tumor–host interactions in glioma at single-cell resolution

Surveying brain tumor heterogeneity by single-cell RNA sequencing of multi-sector biopsies

(2020) Kai Yu et al.   National Science Review

Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response

(2020) Jessica Roelands et al.   Journal for ImmunoTherapy of Cancer

A map of tumor–host interactions in glioma at single-cell resolution

(2020) Francesca Pia Caruso et al.   GigaScience

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

(2019) Junfei Zhao et al.   NATURE MEDICINE

Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

(2019) Davide Bedognetti et al.   Journal for ImmunoTherapy of Cancer

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

(2019) Cyril Neftel et al.   CELL

Hedgehog Signaling: An Achilles’ Heel in Cancer

(2019) Madiha Niyaz et al.   Translational Oncology

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

(2018) Qianghu Wang et al.   CANCER CELL

Recovering Gene Interactions from Single-Cell Data Using Data Diffusion

(2018) David van Dijk et al.   CELL

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

T-cell Dysfunction in Glioblastoma: Applying a New Framework

(2018) Karolina I. Woroniecka et al.   CLINICAL CANCER RESEARCH

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Exponential scaling of single-cell RNA-seq in the past decade

(2018) Valentine Svensson et al.   Nature Protocols

Immune Microenvironment in Glioblastoma Subtypes

(2018) Zhihong Chen et al.   Frontiers in Immunology

Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

(2018) Carlos R. Figueiredo et al.   Frontiers in Immunology

A metabolic function of FGFR3-TACC3 gene fusions in cancer

(2018) Véronique Frattini et al.   NATURE

Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells

(2018) Keren Bahar Halpern et al.   NATURE BIOTECHNOLOGY

Single-cell transcriptome analysis of lineage diversity in high-grade glioma

(2018) Jinzhou Yuan et al.   Genome Medicine

Evolution of Metastases in Space and Time under Immune Selection

(2018) Mihaela Angelova et al.   CELL

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy

(2018) Razvan Cristescu et al.   SCIENCE

CD90 determined two subpopulations of glioma-associated mesenchymal stem cells with different roles in tumour progression

(2018) Qing Zhang et al.   Cell Death & Disease

Integrin CD11b activation drives anti-tumor innate immunity

(2018) Michael C. Schmid et al.   Nature Communications

Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

(2018) Manu P. Kumar et al.   Cell Reports

Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing

(2018) Simon Joost et al.   Cell Reports

The Ribosomal Protein S19 Suppresses Antitumor Immune Responses via the Complement C5a Receptor 1

(2017) Maciej M. Markiewski et al.   JOURNAL OF IMMUNOLOGY

HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss

(2017) C H Shin et al.   ONCOGENE

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

(2017) Andrew S. Venteicher et al.   SCIENCE

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine

(2017) Katharina J. Wenger et al.   Oncology Letters

Contactin-2/TAG-1, active on the front line for three decades

(2017) Tomoyuki Masuda   Cell Adhesion & Migration

Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma

(2017) Spyros Darmanis et al.   Cell Reports

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

(2017) Pornpimol Charoentong et al.   Cell Reports

The Role of Integrins α M β 2 (Mac-1, CD11b/CD18) and α D β 2 (CD11d/CD18) in Macrophage Fusion

(2016) Nataly P. Podolnikova et al.   AMERICAN JOURNAL OF PATHOLOGY

MIF Maintains the Tumorigenic Capacity of Brain Tumor-Initiating Cells by Directly Inhibiting p53

(2016) R. Fukaya et al.   CANCER RESEARCH

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

Disentangling the relationship between tumor genetic programs and immune responsiveness

(2016) Davide Bedognetti et al.   CURRENT OPINION IN IMMUNOLOGY

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

(2016) Itay Tirosh et al.   NATURE

Development of immuno-oncology drugs — from CTLA4 to PD1 to the next generations

(2016) Axel Hoos   NATURE REVIEWS DRUG DISCOVERY

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

(2016) Christine E. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

MIF-CD74 signaling impedes microglial M1 polarization and facilitates brain tumorigenesis

(2016) A Ghoochani et al.   ONCOGENE

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

T cell exclusion, immune privilege, and the tumor microenvironment

(2015) J. A. Joyce et al.   SCIENCE

A draft network of ligand–receptor-mediated multicellular signalling in human

(2015) Jordan A. Ramilowski et al.   Nature Communications

MIF Receptor CD74 is Restricted to Microglia/Macrophages, Associated with a M1-Polarized Immune Milieu and Prolonged Patient Survival in Gliomas

(2014) Pia S. Zeiner et al.   BRAIN PATHOLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling

(2014) Feng Hu et al.   NEURO-ONCOLOGY

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

LRP2 Is an Auxiliary SHH Receptor Required to Condition the Forebrain Ventral Midline for Inductive Signals

(2012) Annabel Christ et al.   DEVELOPMENTAL CELL

Lymphotoxin   Receptor Activation on Macrophages Induces Cross-Tolerance to TLR4 and TLR9 Ligands

(2012) N. Wimmer et al.   JOURNAL OF IMMUNOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

(2010) Judit Anido et al.   CANCER CELL

Ligation of TLR2 by Versican: A Link Between Inflammation and Metastasis

(2009) Wei Wang et al.   ARCHIVES OF MEDICAL RESEARCH

Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas

(2009) O Martinho et al.   BRITISH JOURNAL OF CANCER

The Expression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor by Regulatory Macrophages

(2009) J. P. Edwards et al.   JOURNAL OF IMMUNOLOGY

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

The Chemokine CXCL16 and Its Receptor, CXCR6, as Markers and Promoters of Inflammation-Associated Cancers

(2009) Merav Darash-Yahana et al.   PLoS One

Immunomodulatory effects of BXL-01-0029, a less hypercalcemic vitamin D analogue, in human cardiomyocytes and T cells

(2008) M. Sottili et al.   EXPERIMENTAL CELL RESEARCH