HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical Study

Factors associated with durable EFS in adult B-cell ALL patients achieving MRD-negative CR after CD19 CAR-T cells

(2019) Kevin A. Hay et al.   BLOOD

Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation—a phase I/II study

(2019) Marthe C. J. Roex et al.   LEUKEMIA

Prevention and treatment of relapse after stem cell transplantation by cellular therapies

(2018) Fred Falkenburg et al.   BONE MARROW TRANSPLANTATION

CD4 Donor Lymphocyte Infusion Can Cause Conversion of Chimerism Without GVHD by Inducing Immune Responses Targeting Minor Histocompatibility Antigens in HLA Class II

(2018) Peter van Balen et al.   Frontiers in Immunology

Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response

(2017) Cornelis A.M. van Bergen et al.   JOURNAL OF CLINICAL INVESTIGATION

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

(2017) Ifigeneia Tzannou et al.   JOURNAL OF CLINICAL ONCOLOGY

Multi-state analysis illustrates treatment success after stem cell transplantation for acute myeloid leukemia followed by donor lymphocyte infusion

(2016) Matthias Eefting et al.   HAEMATOLOGICA

Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies

(2016) M. J. Pont et al.   PLoS One

Multi-state analysis illustrates treatment success after stem cell transplantation for acute myeloid leukemia followed by donor lymphocyte infusion

(2016) Matthias Eefting et al.   HAEMATOLOGICA

Autosomal Minor Histocompatibility Antigens: How Genetic Variants Create Diversity in Immune Targets

(2016) Marieke Griffioen et al.   Frontiers in Immunology

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application

(2015) M. J. Pont et al.   HAEMATOLOGICA

Preventing stem cell transplantation-associated viral infections using T-cell therapy

(2015) Ifigeneia Tzannou et al.   Immunotherapy

Allo-reactive T cells for the treatment of hematological malignancies

(2015) J.H.F. Falkenburg et al.   Molecular Oncology

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application

(2015) M. J. Pont et al.   HAEMATOLOGICA

Possible Role of Minor H Antigens in the Persistence of Donor Chimerism after Stem Cell Transplantation; Relevance for Sustained Leukemia Remission

(2015) Cornelis R. van der Torren et al.   PLoS One

Myeloablative T cell-depleted alloSCT with early sequential prophylactic donor lymphocyte infusion is an efficient and safe post-remission treatment for adult ALL

(2013) M Eefting et al.   BONE MARROW TRANSPLANTATION

A Good Manufacturing Practice procedure to engineer donor virus-specific T cells into potent anti-leukemic effector cells

(2013) M. M. van Loenen et al.   HAEMATOLOGICA

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

(2013) Richard A. Morgan et al.   JOURNAL OF IMMUNOTHERAPY

Association of Disparities in Known Minor Histocompatibility Antigens with Relapse-Free Survival and Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation

(2012) Willemijn Hobo et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Generation and administration of HA-1-specific T-cell lines for the treatment of patients with relapsed leukemia after allogeneic stem cell transplantation: a pilot study

(2012) P. Meij et al.   HAEMATOLOGICA

Effective Treatment of Refractory CMV Reactivation After Allogeneic Stem Cell Transplantation With In Vitro-generated CMV pp65-specific CD8+ T-cell Lines

(2012) Pauline Meij et al.   JOURNAL OF IMMUNOTHERAPY

Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

(2011) Paul F. Robbins et al.   JOURNAL OF CLINICAL ONCOLOGY

NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-Tumor/Leukemia Reaction

(2010) Jeffrey S. Miller et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation

(2010) T. Feuchtinger et al.   BLOOD

High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning

(2010) C. A. M. Van Bergen et al.   CANCER RESEARCH

Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies

(2010) M. M. van Loenen et al.   HAEMATOLOGICA

Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity

(2009) A. N. Stumpf et al.   BLOOD

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

(2009) L. A. Johnson et al.   BLOOD

Rapid Identification of Clinical Relevant Minor Histocompatibility Antigens via Genome-Wide Zygosity-Genotype Correlation Analysis

(2009) R. M. Spaapen et al.   CLINICAL CANCER RESEARCH

Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells

(2008) W. J. Norde et al.   BLOOD

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

(2008) Martin A Pule et al.   NATURE MEDICINE

Identification of phosphatidylinositol 4-kinase type II   as HLA class II-restricted target in graft versus leukemia reactivity

(2008) M. Griffioen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA