G-CSF and G-CSFR Modulate CD4 and CD8 T Cell Responses to Promote Colon Tumor Growth and Are Potential Therapeutic Targets

Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage

(2019) Mark A. Glaire et al.   BRITISH JOURNAL OF CANCER

Regulatory γδ T cells induced by G-CSF participate in acute graft-versus-host disease regulation in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation

(2018) Li Xuan et al.   Journal of Translational Medicine

Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity

(2018) Marka R. Crittenden et al.   Scientific Reports

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

T lymphocyte subsets in cancer immunity: Friends or foes

(2018) Dounia Chraa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Colorectal cancer cells suppress CD4+ T cells immunity through canonical Wnt signaling

(2017) Xuan Sun et al.   Oncotarget

Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response

(2016) Kristina Berg Lorvik et al.   CANCER RESEARCH

Granulocyte colony-stimulating factor impairs CD8+T cell functionality by interfering with central activation elements

(2016) C. E. Bunse et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

G-CSF–Induced Suppressor IL-10+Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way

(2016) Suelen Martins Perobelli et al.   JOURNAL OF IMMUNOLOGY

Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers

(2016) Takuro Saito et al.   NATURE MEDICINE

Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer

(2016) Eleonora Timperi et al.   OncoImmunology

Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer

(2015) F Amicarella et al.   GUT

Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting protective NK cell, macrophage and T cell responses

(2015) Katherine T. Morris et al.   Oncotarget

The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer

(2015) Mahiru Kawano et al.   Scientific Reports

G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer

(2015) Maija Hollmén et al.   OncoImmunology

Heterogeneity in the Differentiation and Function of CD8+ T Cells

(2014) Hans-Willi Mittrücker et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration

(2014) K T Morris et al.   BRITISH JOURNAL OF CANCER

PD-1/SHP-2 Inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment

(2014) J. Li et al.   CANCER RESEARCH

Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis

(2014) Kepeng Wang et al.   IMMUNITY

An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

(2013) Alicia S Chung et al.   NATURE MEDICINE

Natural and Induced T Regulatory Cells in Cancer

(2013) Dennis O. Adeegbe et al.   Frontiers in Immunology

Granulocyte-colony stimulating factor promotes proliferation, migration and invasion in glioma cells

(2012) Juntao Wang et al.   CANCER BIOLOGY & THERAPY

Role of IL-17A in the development of colitis-associated cancer

(2012) Y. S. Hyun et al.   CARCINOGENESIS

Human Regulatory T Cells of G-CSF Mobilized Allogeneic Stem Cell Donors Qualify for Clinical Application

(2012) Sya N. Ukena et al.   PLoS One

G-CSF downregulates natural killer cell-mediated cytotoxicity in donors for hematopoietic SCT

(2011) Y-C Su et al.   BONE MARROW TRANSPLANTATION

Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction

(2011) Bernhard Mlecnik et al.   JOURNAL OF CLINICAL ONCOLOGY

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

(2011) Lucia De Monte et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Granulocyte colony-stimulating factor expression as a prognostic biomarker in non-small cell lung cancer

(2011) G. Stathopoulos   ONCOLOGY REPORTS

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Granulocyte-colony-stimulatory factor: a strong inhibitor of natural killer cell function

(2010) Laura Schlahsa et al.   TRANSFUSION

Granulocyte Colony-Stimulating Factor Induced Acute and Chronic Graft-Versus-Host Disease

(2010) Olle Ringden et al.   TRANSPLANTATION

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Prostate Cancer-Producing Granulocyte Colony-Stimulating Factor

(2009) Yoh Matsuoka et al.   UROLOGIA INTERNATIONALIS