Tumor-derived HMGB1 induces CD62Ldim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A head-to-tail view of L-selectin and its impact on neutrophil behaviour

(2018) Aleksandar Ivetic   CELL AND TISSUE RESEARCH

Hypoxia-induced HMGB1 expression of HCC promotes tumor invasiveness and metastasis via regulating macrophage-derived IL-6

(2018) Jiang Jiang et al.   EXPERIMENTAL CELL RESEARCH

Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis

(2018) Dirk J. van der Windt et al.   HEPATOLOGY

Getting DAMP(s) Wets the Whistle for Neutrophil Recruitment

(2018) Emily R. Watts et al.   IMMUNITY

HMGB1 released by irradiated tumor cells promotes living tumor cell proliferation via paracrine effect

(2018) Sijia He et al.   Cell Death & Disease

Chronic lymphocytic leukemia cells increase neutrophils survival and promote their differentiation into CD16high CD62Ldim immunosuppressive subset

(2018) Enrique Podaza et al.   INTERNATIONAL JOURNAL OF CANCER

Primary immunodeficiencies reveal the essential role of tissue neutrophils in periodontitis

(2018) Lakmali M. Silva et al.   IMMUNOLOGICAL REVIEWS

Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

(2018) WonJae Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils in Homeostasis, Immunity, and Cancer

(2017) José Ángel Nicolás-Ávila et al.   IMMUNITY

NET-producing CD16highCD62Ldimneutrophils migrate to tumor sites and predict improved survival in patients with HNSCC

(2017) Camilla Rydberg Millrud et al.   INTERNATIONAL JOURNAL OF CANCER

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

L-selectin mechanochemistry restricts neutrophil priming in vivo

(2017) Zhenghui Liu et al.   Nature Communications

Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

(2017) Maria Ouzounova et al.   Nature Communications

Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils

(2016) Yanfang Liu et al.   CANCER CELL

Toll-like receptor 2 in host defense against Mycobacterium tuberculosis : to be or not to be — that is the question

(2016) Archana Gopalakrishnan et al.   CURRENT OPINION IN IMMUNOLOGY

Reduced Oxidative Burst by Primed Neutrophils in the Elderly Individuals Is Associated With Increased Levels of the CD16bright/CD62LdimImmunosuppressive Subset

(2016) Delphine Sauce et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Gradient Infiltration of Neutrophil Extracellular Traps in Colon Cancer and Evidence for Their Involvement in Tumour Growth

(2016) Stella Arelaki et al.   PLoS One

Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9

(2015) Yao Liu et al.   JOURNAL OF HEPATOLOGY

Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer

(2015) Jitka Y. Sagiv et al.   Cell Reports

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

(2014) Tobias Bald et al.   NATURE

HMGB1 in Cancer: Good, Bad, or Both?

(2013) R. Kang et al.   CLINICAL CANCER RESEARCH

Tissue Damage-Associated "Danger Signals" Influence T-cell Responses That Promote the Progression of Preneoplasia to Cancer

(2012) Y. He et al.   CANCER RESEARCH

Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma

(2012) S. Jube et al.   CANCER RESEARCH

HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction

(2012) Eva Polanská et al.   CHROMOSOMA

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Knockdown of HMGB1 in Tumor Cells Attenuates Their Ability To Induce Regulatory T Cells and Uncovers Naturally Acquired CD8 T Cell-Dependent Antitumor Immunity

(2011) Z. Liu et al.   JOURNAL OF IMMUNOLOGY

TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells

(2010) Deepak Mittal et al.   EMBO JOURNAL

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Suppression of Dendritic Cells by HMGB1 Is Associated with Lymph Node Metastasis of Human Colon Cancer

(2009) Akiko Kusume et al.   PATHOBIOLOGY

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

(2009) James F Curtin et al.   PLOS MEDICINE