Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in hepatocellular carcinoma cells through the mitophagy pathway

Title

Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in hepatocellular carcinoma cells through the mitophagy pathway

Authors

Keywords

Mitochondria, long noncoding RNA, MALAT1, metabolic reprogramming, apoptosis, mitophagy, hepatocellular carcinomaThis study identified the nuclear genome-encoded lncRNA , MALAT1, as a nucleus-to-mitochondria epigenetic messenger that controls metabolic reprogramming by regulating mitochondrial function in hepatocellular carcinoma cells

Journal

Molecular Therapy-Nucleic Acids

Volume -, Issue -, Pages -

Publisher

Elsevier BV

Online

2020-10-04

DOI

10.1016/j.omtn.2020.09.040